Results 131 to 140 of about 50,758 (257)
Renal Disease Burden in Prurigo Nodularis: A Systematic Review and Meta‐Analysis
International Journal of Dermatology, EarlyView.
Natalia Chalupczak +3 more
wiley +1 more source
Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler +2 more
wiley +1 more source
Gut Microbiota‐Linked Benefits of Low‐Intensity Pulsed Ultrasound Rejuvenate the Ageing Muscle
ABSTRACT Background Ageing is an inevitable biological process that contributes to increased prevalence of age‐associated diseases, including sarcopenia, defined by progressive loss of muscle mass, functional decline and a heightened risk of injury. Developing effective interventions remains a critical clinical priority.
Jia‐Hua Jhuang +4 more
wiley +1 more source
Redox Regulation and Oxidative Stress in Health and Disease: Mechanisms and Therapeutic Targeting
Reactive species serve crucial roles which are tightly regulated in both physiological as well as disease states. At physiological levels, these species are integral to redox signaling, while uncontrolled redox promotes disease pathology. This review examines the dysregulation of these processes.
Mohammad Hossein Azadi +2 more
wiley +1 more source
Feet in Peril: Assessment of Feet in Patients Undergoing Haemodialysis
ABSTRACT Background Foot problems are common in haemodialysis patients, making treatment and disease management difficult due to their serious complications and creating a significant financial burden on healthcare expenses. Objective In this study, we assessed the foot problems in haemodialysis patients.
Aysun Ünal +4 more
wiley +1 more source
Background & Aim: New graduate nurses suffer high levels of stress which can lead to unpleasant personal and professional outcomes. The aim of this study was to investigate the role of mindfulness and meta-emotion on predicting Emotional Adjustment in ...
K Babaei Nadinluye +4 more
doaj
Effects of Renal and Hepatic Impairment on the Pharmacokinetics of Zilurgisertib
Aim Small‐molecule activin receptor‐like kinase‐2 inhibitor zilurgisertib (INCB000928) is under investigation in a pivotal trial for the treatment of fibrodysplasia ossificans progressiva (FOP), an ultrarare genetic condition. This analysis assessed effects of renal and hepatic impairment on zilurgisertib pharmacokinetics.
Yan‐ou Yang +5 more
wiley +1 more source
ABSTRACT Background Upadacitinib (UPA) is the first oral Janus kinase (JAK) inhibitor approved for the treatment of Crohn's disease (CD). Real‐world data, particularly from large nationwide cohorts, remain limited. This study aimed to evaluate the real‐world effectiveness, safety, and treatment persistence of UPA in patients with CD.
M. Iborra +51 more
wiley +1 more source
ABSTRACT Background Abnormal accumulation of lipids within the kidney contributes to the progression of chronic kidney disease, but the underlying metabolic mechanisms remain unclear. Citrate is a central metabolite in cellular energy regulation and is frequently elevated in advanced kidney disease, yet its impact on renal lipid metabolism has not been
Marta Sanz‐Gómez +8 more
wiley +1 more source

