ABSTRACT Introduction Chronic kidney disease can present changes in thoracic cavity volume and respiratory muscle weakness, even in the pre‐dialysis stage. However, there is little evidence on the effects of inspiratory muscle training in these patients.
Mônica Soares de Oliveira +6 more
wiley +1 more source
Klotho deficiency and cognitive impairment in dialysis patients: mechanisms, clinical evidence, and therapeutic implications. [PDF]
Hu W, Kong Y, Wang J.
europepmc +1 more source
EvoMut: A computational framework for engineering oxidative stability in proteins
Abstract Amino acid oxidation is a major cause of protein instability and loss of function in therapeutic and industrial settings. Although methionine, cysteine, tryptophan, tyrosine, histidine, lysine, and arginine residues are widely recognized as oxidation‐prone, only a subset of such residues is dominant functional hotspots, and not all are ...
Seyed Shahriar Arab +2 more
wiley +1 more source
Early-Onset Dialysis Disequilibrium Syndrome Presenting With Hypoxia and Subtle Neurological Signs During Initial Hemodialysis. [PDF]
Tahir MH, Tahir F, Asghar S.
europepmc +1 more source
ABSTRACT Type 2 diabetes mellitus (T2DM) has increasingly been identified as a risk factor for sensorineural hearing loss, whereas the association between different antidiabetic therapies and hearing thresholds remains poorly characterized. This retrospective observational study evaluated 240 patients with T2DM and 105 normoglycemic controls who ...
Francesco Martines +8 more
wiley +1 more source
Uremic pancreatitis following routine initiation of losartan in advanced chronic kidney disease: A case report. [PDF]
Yan VC +7 more
europepmc +1 more source
Renal Impairment Does Not Affect Pharmacokinetics, Safety or Tolerability of Zenagamtide
ABSTRACT Aims Zenagamtide is a novel, unimolecular glucagon‐like peptide‐1 and amylin receptor agonist in development for weight management and Type 2 diabetes. This study investigated the pharmacokinetic (PK) properties, safety and tolerability of zenagamtide in participants with various degrees of renal impairment versus participants with normal ...
Lykke Ida Kaas Oldenburg +6 more
wiley +1 more source
MLP-CKD: a clinically informed deep learning framework for admission laboratory-based screening and risk stratification of uremia-associated advanced renal dysfunction. [PDF]
Chen X +6 more
europepmc +1 more source
Soluble immune checkpoints, anti‐HLA panel‐reactive antibodies, and kidney function parameters were evaluated to investigate their associations with early graft function. Pre‐transplant patients showed higher levels of sCD25, sPD‐L1, sTIM‐3, Gal‐9, sCD27, and sPD‐L2 than healthy controls, while post‐transplant temporal changes were observed in sCD25 ...
Cemil Pehlivanoğlu +8 more
wiley +1 more source
Diagnostic Overlap Between Uremia and Severe Hyperkalemia in Chronic Kidney Disease: Emphasizing Laboratory-Guided Urgency Despite Absent EKG Changes. [PDF]
Tahir MH +4 more
europepmc +1 more source

