Results 71 to 80 of about 9,061,852 (330)

A brief review of the literature on the malignant ureteral obstruction [PDF]

, 2018
Malignant ureteral obstruction (MUO) caused by a primarily urological tumor or secondary to a late-stage malignancy can be difficult for the urologist to manage. Due to a lack of clinical data on the management of MUO, every case is particular and should
Brînză, Adrian, Lupu, Sorin, Marcu, Dragos, Maxim, Laurian, Neagu, Tiberiu P, Peride, Ileana, Socea, Bogdan, Stanescu, Ana Maria Alexandra   +7 more
core   +1 more source

The role of mutation rate variation and genetic diversity in the architecture of human disease [PDF]

, 2013
We have investigated the role that the mutation rate and the structure of genetic variation at a locus play in determining whether a gene is involved in disease. We predict that the mutation rate and its genetic diversity should be higher in genes associated with disease, unless all genes that could cause disease have already been identified ...
arxiv   +1 more source

Unveiling new disease, pathway, and gene associations via multi-scale neural networks [PDF]

PLOS ONE, 15(4), p.e0231059 (2020), 2019
Diseases involve complex processes and modifications to the cellular machinery. The gene expression profile of the affected cells contains characteristic patterns linked to a disease. Hence, biological knowledge pertaining to a disease can be derived from a patient cell's profile, improving our diagnosis ability, as well as our grasp of disease risks ...
arxiv   +1 more source

Metformin Prevents Renal Fibrosis in Mice with Unilateral Ureteral Obstruction and Inhibits Ang II-Induced ECM Production in Renal Fibroblasts

International Journal of Molecular Sciences, 2016
Renal fibrosis is the final common pathway of chronic kidney disease (CKD), and no effective medication is available clinically for managing its progression. Metformin was initially developed as an anti-diabetic drug and recently gained attention for its
Yang Shen, Naijun Miao, Jin-lan Xu, Xinxin Gan, Dan Xu, Li Zhou, H. Xue, Wei Zhang, Li-min Lu   +8 more
semanticscholar   +1 more source

Second Renal Transplantation With Simultaneous Ileal Conduit Creation Following Transplant Nephroureterectomy and Native Cystectomy

IJU Case Reports, EarlyView.
ABSTRACT Introduction Postrenal transplant urothelial carcinoma necessitates multidisciplinary treatment. We here report the first case of a patient with transplant ureteral and bladder cancer who underwent transplant nephroureterectomy and cystectomy, followed by a second living donor renal transplantation and ileal conduit creation after a cancer ...
Ayato Ito, Takehiro Ohyama, Kyoko Minamisono, Sho Nishida, Daiki Iwami   +4 more
wiley   +1 more source

Retroperitoneal fibrosis: a case of a patient (63y/o) treated with low-dose methotrexate (MTX) and 6-methylprednisolone (6-MP) [PDF]

, 2018
Retroperitoneal fibrosis (RPF), is a rare fibroinflammatory disease. The pathogenesis of RPF is still unclear and numerous theories have been reported such as environmental factors, immunologic process, genetic component, local inflammation and advanced
A. Santoro, A. Sili Scavalli, N. Galea, R. Cirocchi, R. Poscia, ROSIELLO, FRANCESCO, V. Riccieri   +6 more
core  

Prospective study to compare antibiosis versus the association of N-acetylcysteine, D-mannose and morinda citrifolia fruit extract in preventing urinary tract infections in patients submitted to urodynamic investigation [PDF]

, 2017
BACKGROUND: The abuse of antimicrobical drugs has increased the resistance of microorganisms to treatments, thus to make urinary tract infections (UTIs) more difficult to eradicate.
Al Rawashdah, S, AL SALHI, Yazan, Carbone, Antonio, Coppola, Gianpietro, Fuschi, Andrea, Leto, Antonino, Maruccia, S, Maurizi, Angela, Mele, Rita, Palleschi, Giovanni, Pastore, ANTONIO LUIGI, Velotti, Gennaro, Zanello, Pp   +12 more
core   +2 more sources

Predictors of Failed Outcomes in Ureteral Reconstruction: A Real-World Retrospective Study

Medicina
Background and Objectives: Ureteral reconstruction is aimed at maintaining ureteral patency without the need for long-term catheters like ureteral stents or percutaneous nephrostomies.
Ching-Shiang Lin, Jian-Ri Lee, Kun-Yuan Chiu, Shian-Shiang Wang, Chuan-Shu Chen, Yu-Ju Lin, Chen-Cheng Che   +6 more
doaj   +1 more source

Quantitative Micro-Computed Tomography Imaging of Vascular Dysfunction in Progressive Kidney Diseases.

Journal of the American Society of Nephrology, 2016
Progressive kidney diseases and renal fibrosis are associated with endothelial injury and capillary rarefaction. However, our understanding of these processes has been hampered by the lack of tools enabling the quantitative and noninvasive monitoring of ...
J. Ehling, J. Bábíčková, F. Gremse, B. Klinkhammer, Sarah C. Baetke, R. Knuechel, F. Kiessling, J. Floege, T. Lammers, P. Boor   +9 more
semanticscholar   +1 more source

Renal screening sonography—A comparative study in a Portuguese basic emergency service

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 8-16, March 2025.
Renal sonography screening aids in clinical decision‐making for patients with suspected renal colic. This study intends to compare the accuracy and pertinence of sonographic findings obtained by a sonographer in a Basic Emergency Service (BES) with that of radiologists at Referral Hospital (RH) in Portugal. Renal sonography screening was able to detect
Sérgio Miravent, Carmen Jiménez, Narciso Barbancho, Manuel Duarte Lobo, Teresa Figueiredo, Carla Gomes, Ion Ratusneac, João Mário Gonçalves, Corina Hasnas, Rui de Almeida   +9 more
wiley   +1 more source