Results 91 to 100 of about 7,694 (256)

Nanozymes in Reactive Oxygen Species‐Dependent Diseases: From Design and Preclinical Studies to Clinical Translation Prospects

open access: yesSmall Structures, EarlyView.
Nanozymes emerge as promising therapeutic agents for reactive oxygen species (ROS)‐dependent diseases, offering advantages over traditional biocatalysts through enhanced stability, tunability, and targeting capabilities. This review explores their mechanisms, design strategies, and clinical progress, emphasizing precision medicine potential.
Lihong Zhou   +8 more
wiley   +1 more source

Diagnostic Ureteroscopy for Cases Clinically Suspected of Carcinoma in Situ of the Upper Urinary Tract [PDF]

open access: yes, 2017
 We elucidate the fate of cases clinically suspected of carcinoma in situ (Cis) of the upper tract with serial ureteroscopy. Of 143 patients who underwent ureteroscopy for suspected upper tract urothelial carcinoma (UTUC) between January 2008 and ...
Araki, Motoo   +7 more
core   +1 more source

Content validation of the new nursing intervention “0565 – ultrasonography: bladder”

open access: yesInternational Journal of Nursing Knowledge, EarlyView.
Abstract Purpose To validate the content of the nursing intervention “0565 – ultrasonography: bladder.” Method The content validation study was conducted from September to November 2022, with a sample of 22 specialists who evaluated the components of the nursing intervention “0565 – ultrasonography: bladder,” according to the Nursing Interventions ...
Vítor Monteiro Moraes   +5 more
wiley   +1 more source

Establishment of a integrative multi-omics expression database CKDdb in the context of chronic kidney disease (CKD) [PDF]

open access: yes, 2017
Complex human traits such as chronic kidney disease (CKD) are a major health and financial burden in modern societies. Currently, the description of the CKD onset and progression at the molecular level is still not fully understood.
Fernandes, Marco, Husi, Holger
core   +1 more source

Lawsuits against the Brazilian Unified Health System regarding Bladder/Ureteral Cancer

open access: yesBrazilian Journal of Oncology
Objective To evaluate the technical notes (TNs) issued by the Center for Technical Support of the Judiciary (Núcleo de Apoio Técnico do Poder Judiciário, NAT-Jus, in Portuguese) of the Brazilian Ministry of Justice regarding lawsuits against ...
Fernando Korkes   +6 more
doaj   +1 more source

Nephron-Sparing Surgery for Upper Urinary Tract Urothelial Carcinoma [PDF]

open access: yesJournal of Urologic Oncology
Radical nephroureterectomy (RNU) remains the gold standard for the surgical management of upper tract urothelial carcinoma (UTUC) from the ureterovesical junction to the renal pelvis. However, the removal of the ipsilateral intact kidney causes morbidity
Sung Han Kim   +2 more
doaj   +1 more source

Blockade of cannabinoid CB1 receptors potentiates the anti‐fibrotic effects mediated by SGLT2 inhibition in a mouse model of diabetic nephropathy

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and purpose Diabetic nephropathy (DN) is a common complication of diabetes. Current treatments include renin‐angiotensin‐aldosterone system (RAAS) blockers and sodium‐glucose co‐transporter 2 (SGLT2) inhibitors. The cannabinoid CB1 receptor is a potential therapeutic target.
Océane Pointeau   +20 more
wiley   +1 more source

Orthotopic ureterocele masquerading as a bladder tumor in a woman with pelvic pain

open access: yesInternational Brazilian Journal of Urology, 2005
Single system orthotopic ureteroceles often present in adulthood are associated with characteristic radiographic findings. We present the case of a 54 year old woman with 8 months of urgency/frequency and pelvic pain that has the cystoscopic appearance ...
David D. Thiel   +2 more
doaj   +1 more source

Lactate and Lactylation in AKI‐to‐CKD: Epigenetic Regulation and Therapeutic Opportunities

open access: yesCell Proliferation, EarlyView.
ABSTRACT Lactate is not only a byproduct of glycolysis, but is also considered an energy source, gluconeogenic precursor, signalling molecule and protein modifier during the process of cellular metabolism. The discovery of lactylation reveals the multifaceted functions of lactate in cellular metabolism and opens new avenues for lactate‐related research.
Yi Hou   +7 more
wiley   +1 more source

Surgical resection and reconstruction after resection of tumors involving the sacropelvic region [PDF]

open access: yes, 2014
Objectives Surgical management of the tumors in the sacropelvic region is a challenging field of spine surgery because of the complex local anatomy and biomechanics.
Lazáry, Áron   +2 more
core   +1 more source

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