Results 71 to 80 of about 116,821 (222)

TRIM59 Drives Bladder Cancer Progression Through E3 Ligase‐Dependent K48‐Linked Degradation of PTRF

Cancer Science, EarlyView.
Schematic model of TRIM59‐driven BLCA progression through K48‐linked ubiquitination and proteasomal degradation of PTRF, leading to AKT activation and c‐Myc upregulation. ABSTRACT Tripartite motif‐containing 59 (TRIM59) is an E3 ubiquitin ligase implicated in multiple malignancies, but its role in bladder cancer (BLCA) remains incompletely understood ...
Junlin Gan, Xuesong Bai, Aijie Zhang, Fei Lin, Hang Tong, Tinghao Li, Ning Xu, Xinyuan Li, Zhou Yu, Hubin Yin   +9 more
wiley   +1 more source

URETERAL METASTASIS AS THE FIRST MANIFESTATION OF ASYMPTOMATIC GASTRIC CANCER [PDF]

Ureteral metastasis from gastric cancer is rare. It is usually diagnosed in the setting of an advanced gastric cancer or on postmortem examination. Isolated ureteral metastasis without involvement of other sites is extremely rare. We describe a 67-year-
ملک زاده, رضا, نوجوان , فاطمه, یزدانبد, عباس   +2 more
core  

The Effect of Distal Ureteral Stone Size Measurements on Spontaneous Passage [PDF]

, 2019
Objective: To investigate the relationship of spontaneous ureteral stone passage with stone size (width-length) and ...
Dursun, MURAT, Ongun, Sakir, Murat Dursun, Şakir Ongün   +3 more
core   +1 more source

10-Year Experience with Reinforced Ureteral Stents for Malignant Ureteral Obstruction

Research and Reports in Urology, 2021
Benoît Vogt,1 Laure-Hélène Blanchet2 1Department of Urology, Polyclinique de Blois, La Chaussée Saint-Victor, 41260, France; 2Department of Public Health, Hôpital Saint-Antoine (AP-HP), Paris, 75012, FranceCorrespondence: Benoît VogtDepartment of Urology,
Vogt B, Blanchet LH
doaj  

Indications for percutaneous nephrostomy in patients with obstructive uropathy due to malignant urogenital neoplasias

International Brazilian Journal of Urology, 2005
INTRODUCTION: Urogenital neoplasias frequently progress with obstructive uropathy due to local spreading or pelvic metastases. The urinary obstruction must be immediately relieved in order to avoid deterioration in these patients.
Frederico R. Romero, Marcos Broglio, Silvio R. Pires, Roberto F. Roca, Ione A. Guibu, Marjo D. Perez   +5 more
doaj   +1 more source

Targeting a Novel AREG+ Dendritic Cell Alleviates Renal Fibrosis Induced by Ischemia–Reperfusion Injury

Cell Proliferation, EarlyView.
Renal IRI induces tubular EMT and fibrosis. CD11c+AREG+ DCs mediate the process via AREG‐EGFR axis, serving as promising therapeutic targets. ABSTRACT Renal ischemia–reperfusion injury (RIRI) is a major cause of acute tubular damage and a key driver of maladaptive repair and fibrosis.
Xin Luo, Longbin Xiong, Zhaohui Zhou, Lihao Zhang, Yulu Peng, Xiangpeng Zou, Yixin Huang, Yisong Lin, Xiaofeng Yang, Zhanji Zhan, Fangjian Zhou, Youhua Liu, Chunping Yu, Baokui Ye, Zhiling Zhang   +14 more
wiley   +1 more source

Left Retrocaval Ureter Associated With Urothelial Malignancy: Presentation of a Rare Case

Urology Journal, 2012
No ...
Diomidis Kozyrakis, Ioannis Prombonas, Vasilios Kyrikos, Alkiviadis Grigorakis, Georgios Pliotas,, Dimitrios Malovrouvas   +5 more
doaj  

Multimodal therapy for primary ureteral small cell neuroendocrine carcinoma with high-grade urothelial component: case report and literature review

Frontiers in Urology
Primary small cell neuroendocrine carcinoma (SCNEC) of the ureter is an exceptionally rare and aggressive malignancy, characterized by rapid progression and poor prognosis.
Yaqi Li, Yugang Deng, Siwei Ma, Jie Liu
doaj   +1 more source

Expression characteristics of dual‐specificity phosphatase 2 and hypoxia‐inducible factor‐1α in acute kidney injury and preliminary study of the effect of dual‐specificity phosphatase 2 on HK‐2 cells

Experimental Physiology, EarlyView.
ABSTRACT Acute kidney injury (AKI) is a global health problem with significant long‐term harm if the prognosis is poor. Dual‐specificity phosphatase 2 (DUSP2) is involved in key regulatory pathways in several disease processes, but its function in renal pathophysiology is unclear.
Xueqian Chu, Songmin Xue, Lanyan Lin, Xuan Huang, Sisi Chen, Wulaer Adeli, Zulibiya Tuohetiyaer, Suhua Li, Chen Lu   +8 more
wiley   +1 more source

Early‐stage 2K1C renovascular hypertension does not increase global MHC‐II or F4/80 abundance in the non‐clipped kidney but reveals focal F4/80+ induction

Experimental Physiology, EarlyView.
Abstract The two‐kidney, one‐clip (2K1C) model produces renovascular hypertension. The effects on the clipped kidney (CK) are well described, while the non‐clipped kidney (NCK) is used as a model to evaluate the effects of high blood pressure. Although most of these effects have been described at later stages of 2K1C hypertension, it remains unclear ...
Pilar Cárdenas, Allison C. León, Juan Castillo‐Geraldo, Catalina Cid‐Salinas, Javiera Saez, Stefanny Figueroa, Javier Reyes, Emma Rosenkoetter, Suarybell Guzmán Román, Carmen De Miguel, Cristián A. Amador, Alexis A Gonzalez   +11 more
wiley   +1 more source