Results 71 to 80 of about 10,708 (218)

TREM2 in Macrophages Promotes Renal Fibrosis via Activation of β‐Catenin Signalling Pathway in Obstructive Nephropathy

Cell Proliferation, EarlyView.
Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) promotes obstructive nephropathy progression by activating the β‐catenin signalling pathway, driving M2 macrophage polarisation, migration and fibrogenic gene expression. targeted inhibition of TREM2 thus represents a promising novel strategy against renal fibrosis.
Jia Wei, Zixia Li, Gengyu Du, Ting Chen, Min Yang, Zhen Yuan, Yidan Zheng, Xiang Yan   +7 more
wiley   +1 more source

Primary lymphoma of the prostate: a rare cause of urinary obstruction

International Brazilian Journal of Urology, 2004
Primary lymphoma of the prostate is rare. It represents 0.09% of prostate neoplasias. The authors report the case of a 42-year old patient presenting urinary obstruction and renal failure due to primary lymphoma of the prostate.
Alberto A. Antunes, Marcos Dall'Oglio, Miguel Srougi   +2 more
doaj   +1 more source

Urothelial Papilloma of the Urinary Bladder in Children: Report of Two Cases

European Journal of Pediatric Surgery Reports, 2020
Urothelial neoplasms of the bladder (UNB) are considerably rare throughout the pediatric population. UNB develops from the urothelial tissue in the form of a benign disease, generally favoring a successful prognosis in the majority of cases.
Kata Davidovics, Sandor Davidovics, Andras Farkas, Noemi Benedek, Tamas Tornoczki, Daniel Kardos, Anna Davidovics, Peter Vajda   +7 more
doaj   +1 more source

Fibroids in obstructed hemivagina and ipsilateral renal anomaly‐like syndrome: Successful hysterectomy and vaginal septoplasty in a kidney transplant recipient with uterus didelphys, vaginal septum and renal agenesis

International Journal of Gynecology &Obstetrics, EarlyView.
Mariana Correia Moreira Cruz, Sophia Helena Batalha, Vitor Matheus Silva, Marcos de Lorenzo Messina, José Maria Soares Junior, Edmund Chada Baracat   +5 more
wiley   +1 more source

Proteolytic remodelling of the extracellular matrix by pericytes

The FEBS Journal, EarlyView.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard, Ella Milne, Kate Qian, Paola Campagnolo, Salvatore Santamaria   +4 more
wiley   +1 more source

The Impact of Primary Tumor Location on Long-Term Oncological Outcomes in Patients with Upper Tract Urothelial Carcinoma Treated with Radical Nephroureterectomy: A Systematic Review and Meta-Analysis

, 2021
Background: Upper tract urothelial carcinoma (UTUC) accounts for up to 10% of all urothelial neoplasms. Currently, various tumor-related factors are proposed to be of importance in UTUC prognostic models; however, the association of the primary UTUC ...
Bartosz Małkiewicz, Michał Sut, Wojciech Krajewski, Roberto Carando, Jeremy Yuen-Chun Teoh, Krzysztof Kaliszewski, Tomasz Szydełko, Joanna Chorbińska, Keiichiro Mori, Łukasz Nowak, Chiara Lonati, Adrian Poterek, Bartłomiej Sporniak, on behalf of the European Association of Urology–Young Academic Urologists (EAU–YAU) Urothelial Carcinoma Working Group on behalf of the European Association of Urology–Young Academic Urologists (EAU–YAU) Urothelial Carcinoma Working Group, Marco Moschini, Paweł Kiełb   +15 more
core   +1 more source

Ureteral tumor in an ectopic duplex system: a case report

Journal of Medical Case Reports, 2019
Introduction Ureteral ectopia is a rarely observed anomaly. It may be totally asymptomatic. An association with a duplex system is exceptional. Diagnostic and therapeutic approaches are challenging. Carcinologic surgery must consider the anatomic variant,
Omar Karray, Hassen Khouni, Mahdi Charfi, Rami Boulma, Mehdi Debaibi, Rym Makhlouf, Karim Bargaoui, Oumeima Nessej, Azza Seridi, Slim Fourti, Mohamed Habib Bouhaouala, Adnene Chouchene   +11 more
doaj   +1 more source

Marked attenuation of P63 expression in plasmacytoid urothelial carcinoma with expanded immunohistochemical framework including E‐cadherin, P120, HER2 and TRPS1

Histopathology, EarlyView.
Plasmacytoid urothelial carcinoma demonstrates marked attenuation of p63 expression together with frequent disruption of the E‐cadherin–p120 adhesion complex, supporting its characteristic discohesive growth pattern. Standardized HER2 scoring identifies a substantial positive subset, highlighting diagnostic pitfalls and potential therapeutic relevance ...
Busra Yaprak Bayrak, Kemal Kosemehmetoglu, Busra Ozbek, Sercan Simsek, Murat Oktay, Ganime Coban, Dilara Irem Arslan Kahraman, Egemen Akıncıoglu, Melek Buyukgok, Selin Colak, Hatice Nese Dogan, Burak Gurel, Selva Kabul, Kerem Karaca, Elif Ozsagir, Ece Ozturk, Havva Serap Toru, Gupse Turan, Nazif Alperen Yıldırım, Ozlem Nur Yıldız, Yasemin Yuyucu Karabulut, Liang Cheng, Mahmut Akgul   +22 more
wiley   +1 more source

Lawsuits against the Brazilian Unified Health System regarding Bladder/Ureteral Cancer

Brazilian Journal of Oncology
Objective To evaluate the technical notes (TNs) issued by the Center for Technical Support of the Judiciary (Núcleo de Apoio Técnico do Poder Judiciário, NAT-Jus, in Portuguese) of the Brazilian Ministry of Justice regarding lawsuits against ...
Fernando Korkes, Mariana Avelar da Silveira, Flavio Tocci, Carlos Pedrotti, Vanessa Damazio Teich, Luciana Holz Camargo de-Barros, Sidney Glinas   +6 more
doaj   +1 more source

Women in space: A review of known physiological adaptations and health perspectives

Experimental Physiology, EarlyView.
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford, Danielle J. Carroll, Heather C. M. Allaway, Bonnie J. Dunbar, Aenor J. Sawyer   +4 more
wiley   +1 more source