Results 51 to 60 of about 116,821 (222)

Masquerading as A Stone: An Unusual Cause of Chronic Ureteric Obstruction

Journal of Urological Surgery, 2021
Amyloidosis is a group of disorders characterized by the extracellular deposition of amorphous, misfolded proteins. Primary localized bladder amyloidosis is a rare form of the disease that usually presents with macroscopic hematuria, irritative lower ...
Oliver van den Broek Best, Lequang Vo, Marcus Handmer, Fiona Maclean, Pascal Mancuso   +4 more
doaj   +1 more source

Gramine Suppresses Myofibroblast Activation and ECM Accumulation in Renal Fibrosis by Targeting the NF‐κB/NLRP3 and TGF‐β1/Smad Pathways

Phytotherapy Research, EarlyView.
ABSTRACT Chronic kidney disease (CKD) is driven by persistent inflammation and progressive fibrosis, leading to irreversible renal damage. Gramine (GMN), an indole alkaloid, has broad pharmacological benefits. However, its therapeutic potential against renal fibrosis remains unexplored.
Shobhit Gairola, Archana Bhatta, Tushar Mishra, Ravinder K. Kaundal   +3 more
wiley   +1 more source

Serous Neoplasms

, 2014
Although interest in pancreatic pathology is very high in the radiological and gastroenterological communities, it is still the case that less is known about pathology of the pancreas than about liver pathology, for example.
Paolo Tinazzi Martini, Giovanni Morana, Stefano Canestrini, Riccardo De Robertis, Roberto Pozzi Mucelli, Paola Capelli, Stefano Gobbo, Mirko D’Onofrio, Claudio Luchini, D’Onofrio Mirko, De Robertis Riccardo, Luchini Claudio, Canestrini Stefano, Gobbo Stefano, Mucelli Roberto Pozzi, Capelli Paola, Martini Paolo Tinazzi, Morana Giovanni   +17 more
core   +2 more sources

Notoginsenoside R2 Antagonizes Renal Interstitial Fibrosis by Regulating Fatty Acid Oxidation via the CASP2/ALDH3A1 Axis

Phytotherapy Research, EarlyView.
Proposed mechanism by which notoginsenoside R2 (NGR2) attenuates renal interstitial fibrosis. In injured renal tubular epithelial cells, CASP2 downregulation and enhanced ubiquitin‐dependent degradation of ALDH3A1 disrupt mitochondria‐associated endoplasmic reticulum membranes (MAMs) and impair fatty acid oxidation (FAO), leading to lipid accumulation ...
Guanting Chen, Tao Li, Zhenzhen Wang, Hao Zhao, Xiaoxia Xun, Yijiao Wang, Shiyuan Jiang, Qing Zhang, Weiwei Sun, Kang Yang, Yaoxian Wang   +10 more
wiley   +1 more source

Mucinous Neoplasms

, 2022
Mucinous cystic neoplasms (MCNs) are thick-walled, uni- or multilocular tumors composed of mucin-containing cysts. These neoplasms occur almost exclusively in women and are mainly located in the body-tail of the pancreas.
D'Onofrio, Mirko, Capelli, Paola, Martini, Paolo Tinazzi, Barbi, Emilio, Luchini, Claudio, De Robertis, Riccardo   +5 more
core   +1 more source

Neoadjuvant versus adjuvant chemotherapy in upper tract urothelial carcinoma: A nationwide cohort study

BMC Urology, 2022
Purpose This study aimed to evaluate the trend of adjuvant chemotherapy (AC) and neoadjuvant chemotherapy (NAC) in patients who underwent radical nephroureterectomy with bladder cuff excision (NUx) for upper tract urothelial carcinoma (UTUC) to compare ...
Jong Hyun Tae, Moon Soo Ha, Byung Hoon Chi, In Ho Chang, Tae-Hyoung Kim, Soon Chul Myung, Tuan Thanh Nguyen, Myoungsuk Kim, Kyung-Eun Lee, Yuwon Kim, Hyun-ki Woo, Dae-Sung Kyoung, Hasung Kim, Se Young Choi   +13 more
doaj   +1 more source

Technology Assisted Intraoperative Anatomic Visualization: Surgeon Perspectives and Unmet Needs

World Journal of Surgery, EarlyView.
Iatrogenic injury to critical anatomic structures remains a leading source of surgical morbidity, most commonly due to visual misperception rather than technical error. Despite a rapidly expanding ecosystem of intraoperative visualization adjuncts, the surgeon's perspective on current limitations and unmet needs has not been evaluated. The objective of
Yann Sakref, Madeline Elizabeth Adams, Peiqi Chen, Zaria Cosby, Kristen Davis‐Lopez, Arden M. Morris, Zhongming Li, F. Christopher Holsinger, Jeffrey K. Jopling, Lisa M. Knowlton   +9 more
wiley   +1 more source

Case Report: A rare case of unilateral renal clear cell carcinoma with synchronous contralateral ureteral metastasis

Frontiers in Oncology
BackgroundRenal cell carcinoma (RCC) rarely metastasizes to the contralateral ureter. Fewer than 10 such cases have been reported, mostly involving clear cell RCC (CCRCC) with associated hydronephrosis and renal insufficiency.
Yichen Qian, Yuanchen Lu, Qijie Zhang, Jianjun Xie, Hua Shen, Junpeng Deng   +5 more
doaj   +1 more source

Risk-adapted scoring model to identify candidates benefiting from adjuvant chemotherapy after radical nephroureterectomy for localized upper urinary tract urothelial carcinoma: A multicenter study [PDF]

Investigative and Clinical Urology
Purpose: Adjuvant chemotherapy (AC) is recommended for muscle-invasive or lymph node-positive upper urinary tract urothelial carcinoma (UTUC) after radical nephroureterectomy (RNU). However, disease recurrences are frequently observed in pT1 disease, and
Sung Jun Sou, Ja Yoon Ku , Kyung Hwan Kim, Won Ik Seo, Hong Koo Ha, Hui Mo Gu, Eu Chang Hwang, Young Joo Park, Chan Ho Lee   +8 more
doaj   +1 more source

Experiences of Women and Clinicians During the Introduction of Uterine Transplantation to the UK: A Qualitative Case Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To explore the experiences of women and clinicians during the introduction of uterine transplantation (UTx) to the UK. Design A qualitative study utilising prospective case study methodology (interviews and observations) over 6 years.
Daisy Elliott, Richard J. Smith, Maeve Coyle, Rhiannon Macefield, Saliha Vali, Anni King, Natalie Blencowe, Cynthia Ochieng, Christin Hoffmann, Isabel Quiroga, Ben P. Jones, Ariadne L'Heveder, Kerry N. L. Avery, Jane M. Blazeby   +13 more
wiley   +1 more source