Results 31 to 40 of about 423,766 (336)

Unilateral Ureteral Obstruction as a Model to Investigate Fibrosis-Attenuating Treatments

Biomolecules, 2019
Renal fibrosis is the common pathway for most forms of progressive renal disease. The Unilateral Ureteral Obstruction (UUO) model is used to cause renal fibrosis, where the primary feature of UUO is tubular injury as a result of obstructed urine flow ...
E. Martínez-Klimova, O. E. Aparicio-Trejo, E. Tapia, J. Pedraza-Chaverri   +3 more
semanticscholar   +1 more source

Alpha8 Integrin (Itga8) Signalling Attenuates Chronic Renal Interstitial Fibrosis by Reducing Fibroblast Activation, Not by Interfering with Regulation of Cell Turnover.

PLoS ONE, 2016
The α8 integrin (Itga8) chain contributes to the regulation of cell proliferation and apoptosis in renal glomerular cells. In unilateral ureteral obstruction Itga8 is de novo expressed in the tubulointerstitium and a deficiency of Itga8 results in more ...
Ines Marek, Till Lichtneger, Nada Cordasic, Karl F Hilgers, Gudrun Volkert, Fabian Fahlbusch, Wolfgang Rascher, Andrea Hartner, Carlos Menendez-Castro   +8 more
doaj   +1 more source

Double trouble: diagnostic dilemma in a rare association of proximal ureteric valve with orthotopic ureterocele—case report

African Journal of Urology, 2020
Background Association of the ureterocele and proximal ureteral valve is a rare congenital anomaly which can lead to quick detoriation of renal function due to double obstruction. Though ureteral valves have been associated with other ureteral anomalies,
Anuj Dumra, P. Ashwin Shekar, Hardik Patel   +2 more
doaj   +1 more source

Endoscopic laser-ablation for the treatment of orthotopic and ectopic ureteroceles in dogs: 13 cases (2008-2017). [PDF]

, 2019
BACKGROUND: Ureteroceles are a rare condition in dogs in which conventional treatments can result in substantial morbidity. Cystoscopic and fluoroscopic-guided laser ablation (CLA) of ureteroceles can successfully relieve obstruction.
Ather MH, Ettinger S, Hoffman S, Martin RA, McLoughlin MA, Ross LA, Scott RC, Stowater JL, Tobias K, Van Batavia JP   +9 more
core   +2 more sources

Unilateral ureteral obstruction causes gut microbial dysbiosis and metabolome disorders contributing to tubulointerstitial fibrosis

Experimental and Molecular Medicine, 2019
Chronic kidney disease (CKD) increases the risk and prevalence of cardiovascular disease (CVD) morbidity and mortality. Recent studies have revealed marked changes in the composition of the microbiome and the metabolome and their potential influence in ...
Lin Chen, Dan-Qian Chen, Jing-Ru Liu, Jun Zhang, N. Vaziri, S. Zhuang, Hua Chen, Ya-long Feng, Yan Guo, Ying-yong Zhao   +9 more
semanticscholar   +1 more source

Serial optical coherence microscopy for label-free volumetric histopathology [PDF]

, 2020
The observation of histopathology using optical microscope is an essential procedure for examination of tissue biopsies or surgically excised specimens in biological and clinical laboratories.
A Azaripour, A Garcia-Sanz, A Li, AA Eddy, AC Ucero, AJ Schain, C Gillett, C Leahy, CW Merkle, D Huang, DS Richardson, E Min, EA Susaki, H Gong, H Tu, H Wang, H-U Dodt, JP Pezacki, JS Iyer, K Tainaka, LP Hariri, M Belle, MJ Farrar, MP Hiorns, MS Jafri, N Renier, N Roberts, O Assayag, R Tomer, RW Evans, S Sridharan, T Ragan, TT Wong, VJ Srinivasan   +33 more
core   +1 more source

Coexisting congenital mid-ureteral stricture and megaureter due to ureterovesical junction obstruction: A case report

Urology Case Reports, 2022
Congenital mid-ureteral strictures (CMS) are rare. Most congenital strictures occur at the ureteropelvic junction or ureterovesical junction, with mid-ureteral strictures accounting for only 4–5% of all cases of ureteral obstruction in children ...
Shotaro Nakanishi, Minoru Miyazato, Kei Tanaka, Namiko Uema, Seiichi Saito   +4 more
doaj   +1 more source

Repetitive ureteral stenting for management of transplant graft ureteral obstruction

International Brazilian Journal of Urology, 2006
PURPOSE: To review the use of repetitive stenting in the management of patients with ureteral obstruction after renal transplantation, with an emphasis on technique and functional graft outcome.
Lester S. Borden Jr, Vernon M. Pais Jr, Dean G. Assimos   +2 more
doaj   +1 more source

The resonance® metallic ureteral stent in the treatment of malignant ureteral obstruction: a prospective observational study

BMC Urology, 2019
BackgroundTo study the outcomes and experiences of using metallic stents in treating patients with malignant ureteral obstruction (MUO), we examined the effects of metallic ureteral stenting using the Cook Resonance® stent in the treatment of MUO ...
J. Miyazaki, M. Onozawa, S. Takahashi, Y. Maekawa, M. Yasuda, K. Wada, Yuji Maeda, T. Masaki, A. Yamaguchi, Masahiko Suzuki, Y. Sakai, T. Kimura, Manabu Takai, Kensaku Seike, T. Hashimoto, Shingo Yamamoto   +15 more
semanticscholar   +1 more source

Novel Omega-3 Fatty Acid Epoxygenase Metabolite Reduces Kidney Fibrosis. [PDF]

, 2016
Cytochrome P450 (CYP) monooxygenases epoxidize the omega-3 polyunsaturated fatty acid (PUFA) docosahexaenoic acid into novel epoxydocosapentaenoic acids (EDPs) that have multiple biological actions.
Hammock, Bruce D, Hye Khan, Md Abdul, Imig, John D, Lee, Kin Sing Stephen, Levick, Scott P, Sharma, Amit   +5 more
core   +3 more sources