Results 31 to 40 of about 19,660 (148)

Association of Posttransplant Circulating 25‐Hydroxyvitamin D and Late‐Onset Infections Among Kidney Transplant Recipients: The Wisconsin Allograft Recipient Database (WisARD)

Transplant Infectious Disease, Volume 27, Issue 2, March/April 2025.
Lower posttransplant circulating 25(OH)D level is significantly associated with a higher incidence of late‐onset infection among kidney transplant recipients, especially urinary tract infections in male recipients. ABSTRACT Introduction Late‐onset infection occurring more than 6 months after transplantation is a major threat to the long‐term survival ...
Zhongyu Yuan, Michal L. Melamed, Sandesh Parajuli, Didier Mandelbrot, Brad C. Astor   +4 more
wiley   +1 more source

Women in space: A review of known physiological adaptations and health perspectives

Experimental Physiology, EarlyView.
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford, Danielle J. Carroll, Heather C. M. Allaway, Bonnie J. Dunbar, Aenor J. Sawyer   +4 more
wiley   +1 more source

A Novel Inhibitor of Methyltransferase SMYD2, AZ505 Protects Against Peritoneal Fibrosis in Mice

Clinical and Experimental Pharmacology and Physiology, Volume 52, Issue 7, July 2025.
AZ505, a highly selective inhibitor of SMYD2, may exhibit an antifibrotic effect in peritoneal fibrosis. ABSTRACT AZ505, a highly selective inhibitor of SMYD2, exhibits an antifibrotic effect in renal fibrosis. Its effect on peritoneal fibrosis remains unexplored.
Taijing Xu, Binbin Cui, Feng Liu, Mengjun Liu, Xiying Hou, Xuan Hong, Hualin Qi   +6 more
wiley   +1 more source

Apoptosis Inhibitor of Macrophages in Cats: A Potential Link Between an Exon 3 Variant Allele and Progression of Naturally Occurring Chronic Kidney Disease

Journal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT Background The protein apoptosis inhibitor of macrophages (AIM) is involved in kidney repair. An AIM (fAIM) genetic variant in cats resulting in a domain duplication might abrogate fAIM's protective effect on kidney function. Objectives To confirm that the domain duplication previously described in fAIM results from an exon duplication at the ...
Gabriela C. L. Evangelista, Julianne K. Hwang, Liam E. Broughton‐Neiswanger, Emily C. Carlo Reis, Michael H. Court, Katrina A. Mealey, Nicolas F. Villarino   +6 more
wiley   +1 more source

Computed Tomographic Analysis of the Anatomical Characteristics of the Canine Prostatic Artery and Development of a Three‐Dimensional Canine Prostate Cancer Model for Simulation of Prostatic Artery Embolization

Veterinary Radiology &Ultrasound, Volume 66, Issue 4, July 2025.
ABSTRACT The prognosis of prostate cancer in male dogs is considered poor to grave, and prostatic artery embolization (PAE) has been proposed as an alternative to traditional treatment options. This study analyzed the anatomical characteristics of the prostatic artery using computed tomographic (CT) angiography and developed a three‐dimensional (3D ...
Jaepung Han, Sunghoon Jeon, Byungjin Kim, Sojin Kim, Jiwoon Park, Uhjin Kim, Jinhwa Chang, Sang‐Hwan Hyun, Dongwoo Chang, Namsoon Lee   +9 more
wiley   +1 more source

Primary Diffuse Large B‐Cell Lymphoma of the Seminal Vesicles: A Rare Case With Diagnostic and Therapeutic Implications

Clinical Case Reports, Volume 13, Issue 6, June 2025.
ABSTRACT Primary diffuse large B‐cell lymphoma of the seminal vesicles is rare but treatable. Multimodal imaging and biopsy confirmed the diagnosis in a 68‐year‐old male. Eight cycles of R‐CHOP chemotherapy achieved a favorable outcome, emphasizing early intervention in atypical pelvic masses.
Mohammad Soleimani, Mostafa Farajpour, Behrang Kazeminejad   +2 more
wiley   +1 more source

Giant Bladder Diverticulum in A Female Infant Mimicking Intraperitoneal Mass

Clinical Case Reports, Volume 13, Issue 6, June 2025.
ABSTRACT Urinary bladder diverticula can be either primary (congenital) or secondary (acquired) and are more commonly observed in males, sometimes in association with syndromes. The condition presents with a wide range of symptoms, while some cases may remain asymptomatic.
Jay Lodhia, Mujaheed Suleman, Samwel Chugulu, Kondo Chilonga, David Msuya   +4 more
wiley   +1 more source

Mechanism Analysis of Zuogui and Yougui Pills on Diabetic Nephropathy Through Transcriptional Regulatory Networks of HIF1A and PPARA

Food Science &Nutrition, Volume 13, Issue 6, June 2025.
The shared mechanisms of Zuogui Pill (ZGP) and Yougui Pill (YGP) for treating diabetic nephropathy is HIF1A‐CA9‐PDK1 and PPARA‐PDK4. ZGP and YGP inhibited renal fibrosis and relieved the decrease in glucose consumption through transcriptional regulatory network of HIF1A and PPARA.
Liansheng Qiao, Xiaopeng Zhao, Anlei Yuan, Chaoqun Liu, Zewen Wang, Xiaoqian Huo, Shijie Bi, Jiaye Tian, Bin Yu, Zhaozhou Lin, Yanling Zhang, Jiwang Zhang   +11 more
wiley   +1 more source

Intradiscal Mesenchymal Stromal Cell Therapy for the Treatment of Low Back Pain Due to Moderate‐to‐Advanced Multilevel Disc Degeneration: A Preliminary Report of a Double‐Blind, Phase IIB Randomized Clinical Trial (DREAM Study)

JOR SPINE, Volume 8, Issue 2, June 2025.
This phase IIB randomized controlled trial evaluated the safety and efficacy of intradiscal injections of autologous bone marrow‐derived mesenchymal stromal cells (BM‐MSCs) in patients with chronic low back pain from moderate‐to‐advanced multilevel disc degeneration.
Gianluca Vadalà, Fabrizio Russo, Cristiana Lavazza, Giorgia Petrucci, Luca Ambrosio, Silvia Budelli, Elisa Montelatici, Giuseppina Di Giacomo, Claudia Cicione, Veronica Tilotta, Giuseppe Francesco Papalia, Matteo Pileri, Amalia Bruno, Salvatore La Rosa, Emilio Carrino, Eliodoro Faiella, Massimiliano Carassiti, Lorenza Lazzari, Rocco Papalia, Vincenzo Denaro   +19 more
wiley   +1 more source

SMYD2 Promotes Renal Tubular Cell Apoptosis and Chronic Kidney Disease Following Cisplatin Nephrotoxicity

The FASEB Journal, Volume 39, Issue 10, 31 May 2025.
SMYD2 mediates the activation of the NF‐κB signaling pathway to promote cisplatin‐induced chronic kidney injury. Cisplatin stimulation induces the upregulation of SMYD2 expression in renal tubular epithelial cells. SMYD2 promotes the phosphorylation of the p65 subunit of NF‐κB through methylation, thereby facilitating the release of inflammatory ...
Siyang Zuo, Huixiong Yuan, Xia Li, Ming Chen, Rui Peng, Siyu Chen, Xue Zou, Yuan Yang, Hehua Long, Zeying Liu, Teng Wang, Bing Guo, Lirong Liu   +12 more
wiley   +1 more source