Results 31 to 40 of about 25,382 (196)
During renal fibrosis, SMAD3 acts as a transcription factor for CRLF1, promoting its expression and secretion. CRLF1 then binds to ITGB1 via an autocrine mechanism, activating the PI3K‐AKT signaling pathway to mediate renal fibrosis. This accelerates the progression from AKI to CKD, highlighting the therapeutic potential of targeting CRLF1 for ...
Chunjie Wang +8 more
wiley +1 more source
The mechanisms of renal fibrogenesis after ureteral obstruction remain unclear. We tried to primarily expand mesenchymal stem cells from renal tissues and then investigated their role in fibrogenesis after ureteral obstruction.
Yong-Hua Peng +4 more
doaj +1 more source
A unique case of Schistosoma‐related ureteral stricture: Diagnosis and surgical reconstruction
Background Chronic infection with Schistosoma haematobium can lead to pathology of the upper and lower urinary tracts. While well known as a cause of squamous cell carcinoma of the bladder, relatively little research exists on ureteral involvement. Here,
Jonathan A Seaman +2 more
doaj +1 more source
Establishment and characterization of mouse lymph node fibrosis models
The design of the entire paper. Schematic illustration of four strategies for establishing mouse lymph node (LN) fibrosis models. The study further compares their fibrotic remodeling patterns and immune alterations. Abstract Background Lymph node (LN) fibrosis occurs in a variety of pathological conditions, including HIV infection, obesity, cancer, and
Yaru Niu +8 more
wiley +1 more source
Recent Advances in Ureteral Stents
A ureteral stent is widely used to drain ureteral obstructions, which allows urine to bypass the obstruction. The double J stent, a representative ureteral stent, has undergone many advancements in material and design recently.
Chan Park, Ji Hoon Shin
doaj +1 more source
Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong +5 more
wiley +1 more source
This comprehensive review highlights the transformative role of 3D printing and bioprinting technologies in the regeneration of female reproductive organs and the treatment of gynecological diseases. Unlike previous overviews that focus narrowly on isolated applications, this work provides an integrative analysis of recent clinical and preclinical ...
Chan Hum Park, In‐Sun Hong
wiley +1 more source
In neonatal bladder masses, benign inflammatory conditions like polypoid cystitis can mimic malignancy on ultrasound. In stable neonates with evidence of infection, short‐interval ultrasound follow‐up after antibiotic therapy allows “diagnosis by resolution.” This conservative approach safely avoids unnecessary invasive procedures while maintaining ...
Davide Meneghesso +4 more
wiley +1 more source
This narrative review synthesises current literature regarding paediatric blunt abdominal trauma imaging. It discusses the diagnostic performance of Focused Assessment with Sonography for Trauma, unenhanced and contrast‐enhanced ultrasound, as well as the impact of clinical decision rules for CT on clinical outcomes and radiation dose savings ...
Gemma Dongwon Lee +5 more
wiley +1 more source

