Results 71 to 80 of about 114,871 (347)

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Pharmacokinetics, safety, tolerability and fluorescence imaging of nizaracianine triflutate administered in three divided doses to healthy volunteers

British Journal of Clinical Pharmacology, EarlyView.
Aim Fluorescence‐guided surgery enhances intraoperative visualization of anatomical structures. Nizaracianine is a near‐infrared fluorescent agent that is exclusively renally cleared in animal models. It enables real‐time ureteral imaging and identification, potentially reduces risk of injury and facilitates assessment before surgical closure.
Lisanne K. A. Neijenhuis, Cedric M. W. Pesch, John V. Frangioni, Alexander L. Vahrmeijer, Jacobus Burggraaf, Naomi B. Klarenbeek   +5 more
wiley   +1 more source

Identification of major congenital malformations based on healthcare databases in France: A proof‐of‐concept study using the epi‐meres nationwide mother–child register

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Besides registries, healthcare databases can provide useful information for assessing the frequency of major congenital malformations (MCMs) and investigating their risk factors, particularly medication exposures. This study aimed to assess the validity of MCMs identification based on French national, comprehensive healthcare databases ...
Tom Duchemin, Lise Marty, Jérôme Drouin, Sara Miranda, Jérémie Botton, Valérie Olié, Alain Weill, Rosemary Dray‐Spira   +7 more
wiley   +1 more source

Preservation of the Thin Distal Urethra in Hypospadias Repair

, 2009
Purpose: We report our experience with preserving the thin distal urethra lacking corpus spongiosum for the treatment of hypospadias. Materials and Methods: From January 1997 to October 1999 we treated primary hypospadias in 77 boys with a mean age of 4 ...
陳世乾, YANG, STEPHEN SHEI DEI; CHEN, YUNG TAI; HSIEH, CHENG HSING; CHEN, SHYH CHYAN   +1 more
core  

A novel approach for urethral catheterization in dromedary camels: a preclinical study

BMC Veterinary Research
Background Urethral obstruction due to urolithiasis is an uncommon problem reported in dromedary camels. Urethral catheterization is recommended as an emergency preliminary alternative to palliative urethrostomy to preserve valuable animals for breeding ...
Mohamed Marzok, Adel I. Almubarak, Khalid M. Alkhodair, Mohamed A. Nazih, Mohamed Tharwat, Mohamed W. El-Sherif   +5 more
doaj   +1 more source

Difficult male urethral catheterization: a review of different approaches

International Brazilian Journal of Urology, 2008
PURPOSE: To review and compare the different methods for difficult male urethral catheterization described in selected literature. MATERIALS AND METHODS: A PubMed search was done with the terms "difficult", "failed", or "complications" and "urethral ...
Carlos Villanueva, George P. Hemstreet III   +1 more
doaj   +1 more source

Bacterial Communities of the Coronal Sulcus and Distal Urethra of Adolescent Males

PLoS ONE, 2012
Lactobacillus-dominated vaginal microbiotas are associated with reproductive health and STI resistance in women, whereas altered microbiotas are associated with bacterial vaginosis (BV), STI risk and poor reproductive outcomes. Putative vaginal taxa have
D. Nelson, Q. Dong, B. Van Der Pol, E. Toh, Baochang Fan, B. Katz, Deming Mi, Ruichen Rong, G. Weinstock, E. Sodergren, J. Fortenberry   +10 more
semanticscholar   +1 more source

Drug‐coated balloons: From conventional designs to next‐generation innovations in vascular therapy

BMEMat, EarlyView.
This review traces the evolution of drug‐coated balloons (DCBs) from conventional designs to next‐generation platforms. We highlight innovations in balloon engineering, coating technologies, and therapeutic agents that enhance localized drug delivery while addressing challenges in efficiency, safety, and biocompatibility for vascular and emerging non ...
Lu Zhang, Jiawei Cui, Jin Wang, Manfred F. Maitz, Rifang Luo, Yunbing Wang   +5 more
wiley   +1 more source

Hydrodissection Technique to Preserve the Thin Distal Urethra When Correcting Chordee without Hypospadias

, 2009
Purpose: We introduce a hydrodissection technique to preserve the thin distal urethra when treating chordee without hypospadias. Materials and Methods: A total of 18 patients with chordee but without hypospadias were surgically treated in 3 years ...
陳世乾;劉詩彬, CHEN, SHYH-CHYAN;LIU, SHIH-PING   +1 more
core  

TRP Channels as Lower Urinary Tract Sensory Targets

Medical Sciences, 2019
Several members of the transient receptor potential (TRP) superfamily, including TRPV1, TRPV2, TRPV4, TRM4, TRPM8 and TRPA1, are expressed in the lower urinary tract (LUT), not only in neuronal fibers innervating the bladder and urethra, but also in the ...
Karl-Erik Andersson
doaj   +1 more source