Results 61 to 70 of about 11,189 (180)

Targeted microwave ablation of localised prostate cancer (VIOLETTE trial): a prospective multicentre study

BJU International, EarlyView.
Objective To assess the oncological outcomes of targeted microwave ablation (TMA) using organ‐based tracking (OBT) Fusion® via KOELIS Trinity® (KOELIS, Meylan, France) in men with intermediate‐risk prostate cancer (PCa): the VIOLETTE trial (ClinicalTrials.gov identifier: NCT04582656) Patients and Method In this prospective phase II, multicentre ...
Nicolas Barry Delongchamps, Alexandre Peltier, Eric Potiron, Franck Bladou, Romain Diamand, Aurel Messas, Jean‐Baptiste Roche, Grégoire Robert, Jean‐Louis Hoepffner, Thierry Piechaud, Julien Anract, Roland van Velthoven   +11 more
wiley   +1 more source

Metastatic Sites in Rare Genitourinary Malignancies and Primary Cancer Sites in Genitourinary Organ Metastases: A Secondary Analysis Using the Japanese Pathological Autopsy Registry Database

European Urology Open Science
Background: The epidemiology of metastases from rare genitourinary cancer and metastases to genitourinary organs from other primary neoplasms remains poorly understood. Objective: To investigate the epidemiology of rare genitourinary metastases from rare
Suguru Oka, Tomohiko Hara, Shinji Ito, Michikata Hayashida, Kazushige Sakaguchi, Shinji Urakami   +5 more
doaj   +1 more source

TREM2 in Macrophages Promotes Renal Fibrosis via Activation of β‐Catenin Signalling Pathway in Obstructive Nephropathy

Cell Proliferation, EarlyView.
Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) promotes obstructive nephropathy progression by activating the β‐catenin signalling pathway, driving M2 macrophage polarisation, migration and fibrogenic gene expression. targeted inhibition of TREM2 thus represents a promising novel strategy against renal fibrosis.
Jia Wei, Zixia Li, Gengyu Du, Ting Chen, Min Yang, Zhen Yuan, Yidan Zheng, Xiang Yan   +7 more
wiley   +1 more source

Association of different treatment modalities for rectal cancer and second primary urinary system neoplasms, findings from SEER

Scientific Reports
This study aimed to evaluate the risk of secondary primary urinary system neoplasms (SPUNs) in patients undergoing different treatment strategies during the perioperative period of rectal cancer (RC) and evalue survial prognostsis of SPUNs. The data were
Na Li, Xuning Wang, Fuxiao Duan, Xinyu Wang, Cheng Zhang   +4 more
doaj   +1 more source

Urethral and bladder dosimetry and urinary toxicity in prostate cancer patients undergoing SBRT with and without intra-prostatic boost

Clinical and Translational Radiation Oncology
Background and purpose: To evaluate the dosimetric and toxicity profiles of stereotactic body radiotherapy (SBRT) for prostate cancer, comparing cohorts with and without intraprostatic boost (IPB) to assess feasibility and safety of IPB, with particular ...
Nisha Bhargava, Martina Hurwitz, Josephine Levey, Lily Bennett, Joseph A. Aronovitz, Daniel R. Schmidt, Jonathan W. Lischalk, Irving D. Kaplan, Nima Aghdam   +8 more
doaj   +1 more source

Surgical excision of melanomas in the anal region and reconstruction of the anus in 11 horses

Equine Veterinary Education, EarlyView.
Summary This case report describes the surgical excision of large perianal and perineal melanomas, and reconstruction of the anus in 11 grey horses. Four horses had a history of painful defaecation or urination due to extensive tumours. Seven horses had no clinical signs at the time of admission but had rapidly growing nodules around the anus with ...
F. Somm, A. E. Fürst, M. A. Jackson
wiley   +1 more source

Anti‐Proliferative Effects of Resveratrol on Gingival Fibroblasts Derived From Amlodipine‐Induced Gingival Overgrowth

Journal of Periodontal Research, EarlyView.
Resveratrol in repeated doses has been shown to suppress excessive cell proliferation without cytotoxic effects in amlodipine‐induced gingival hyperplasia, while not having a negative effect on mediators involved in tissue homeostasis in healthy cells, and at the same time, it reduces the expression of biomarkers involved in fibrosis processes ...
Bilkan Kara, Nuriye Işıl Saygun, Cansel Köse Özkan, Melis Özgül Slezovic, Muhittin Abdulkadir Serdar, Mualla Pınar Elçi, Alpdoğan Kantarci   +6 more
wiley   +1 more source

Detection of renal tubular transporter proteins in canine urinary extracellular vesicles using liquid chromatography–tandem mass spectrometry

Veterinary Clinical Pathology, EarlyView.
Abstract Urinary extracellular vesicles (UEVs) are membranous particles that carry renal tubular transporter proteins. Here, we evaluate whether selected renal tubular transporter proteins can be detected in UEVs isolated from small volume (1–5 mL) canine urine samples of healthy dogs and canine patients with elevated circulating parathyroid hormone ...
L. J. McGravey, P. R. Antrobus, T. L. Williams   +2 more
wiley   +1 more source

Dermatological Adverse Events Associated With Lapatinib Treatment in Dogs With Urothelial Carcinoma: A Retrospective Study

Veterinary Dermatology, EarlyView.
Lapatinib is widely used in human oncology; however, dermatological adverse events (DAEs) are common and have been correlated with treatment efficacy. In veterinary medicine, lapatinib use in combination with piroxicam has been shown to be effective in treating canine urothelial carcinoma (UC); however, the incidence and prognostic significance of DAEs
Kosuke Horita, Tomohiro Yonezawa, Yasuyuki Momoi, Shingo Maeda   +3 more
wiley   +1 more source

Laparoscopic stapled partial cystectomy with intraoperative cystourethroscopy for urothelial carcinoma in two dogs

Veterinary Surgery, EarlyView.
Abstract Objective To describe the procedure and short‐term outcomes of two dogs that underwent laparoscopic stapled partial cystectomy with intraoperative cystoscopy for excision of solitary, non‐trigonal, urothelial carcinoma lesions. Animals A 12‐year‐old female spayed mixed breed and a 13‐year‐old female spayed Siberian Husky.
Maureen A. Griffin, Christian Folk, Nicole J. Buote   +2 more
wiley   +1 more source