Results 91 to 100 of about 229,229 (334)
Association of serum uric acid with high-sensitivity C-reactive protein in postmenopausal women. [PDF]
, 2016 OBJECTIVES: To explore the independent correlation between serum uric acid and low-grade inflammation (measured by high-sensitivity C-reactive protein, hs-CRP) in postmenopausal women.
Darabi, H +6 more
core +1 more source
JAMA: The Journal of the American Medical Association, 1905 Washington, D. C., May 13, 1905. To the Editor: —Referring to the announcement on page 1547 ofThe Journalof May 13. as to republication of the series of articles on immunity, permit me to express the hope that the series of valuable papers on uric acid will also be republished in book form and under the author's name. [Editor's Note: The editorials
openaire +2 more sources
ATF3 Deficiency Exacerbates Ageing‐Induced Atherosclerosis and Clinical Intervention Strategy
Advanced Science, EarlyView.Targeting ATF3 with terazosin to against VSMC Senescence and atherosclerosis. TZ reduces the binding affinity of YTHDF2 to Atf3 mRNA, while enhancing mRNA stability. ATF3 promotes Atg7 transcription, enhancing autophagy. ATG7 binds to ATF3 in the cytoplasm, facilitating ATF3 translocation to the nucleus and establishing positive feedback. By modulating
Hao Nie +11 more
wiley +1 more source
PLoS ONEUric acid induces radical oxygen species formation, endothelial inflammation, and endothelial dysfunction which contributes to the progression of atherosclerosis.
Karel H van der Pol +13 more
doaj +1 more source
Association of serum uric acid with proteinuria in type 2 diabetic patients [PDF]
, 2013 Background: Various findings suggest that uric acid is an inflammatory factor and may have a role in endothelial dysfunction and act as a mediator of diabetic nephropathy.
Baradaran, A. +3 more
core +3 more sources
Interaction of nitrogen dioxide with human plasma Antioxidant depletion and oxidative damage [PDF]
, 1992 Nitrogen dioxide (NO*2) is often present in inhaled air and may be generated in vivo from nitric oxide. Exposure of human blood plasma to NO*2 caused rapid losses of ascorbic acid, uric acid and protein thiol groups, as well as lipid peroxidation and ...
Cross, Carroll E. +6 more
core +1 more source
Advanced Science, EarlyView.This study develops a cartilage‐targeted DNA origami system (OCS) that protects and delivers si‐Stat3 to chondrocytes. OCS reduces MMP13 expression, enhances extracellular matrix stability, and lowers oxidative stress while improving cell survival. In vivo, OCS decreases cartilage degradation biomarkers and promotes tissue repair factors, demonstrating
Qi Lv +8 more
wiley +1 more source
Sacubitril/valsartan reduces serum uric acid concentration, an independent predictor of adverse outcomes in PARADIGM-HF [PDF]
, 2017 Aims: Elevated serum uric acid concentration (SUA) has been associated with an increased risk of cardiovascular disease, but this may be due to unmeasured confounders.
Chen, Chen-Huan +16 more
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Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset
Advanced Science, EarlyView.This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu +9 more
wiley +1 more source
Gambaran Kadar Asam Urat Darah Pada Mahasiswa Angkatan 2011 Fakultas Kedokteran Universitas Sam Ratulangi Dengan Indeks Massa Tubuh 18,5-22,9 Kg/m2 [PDF]
, 2013 : Increased uric acid levels (hyperuricemia) play a role in the level of morbidity in several diseases. The prevalence of hyperuricemia in Manado and Minahasa is high compared to other regions in Indonesia. Hyperuricemia can occur at a young age.
Kaligis, S. (Stefana) +2 more
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