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The American Journal of Medicine, 1968
Urinary tract stones were known in prehistoric times. The oldest stone was unearthed in upper Egypt, dated approximately 4800 B.C. (Shattock, 1905). Stones have been discovered from Egyptian mummies of different dynasties (Miller, 1929; Wesson, 1935; Guthrie, 1946; Sigerist, 1951; Butt, 1956).
A B, Gutman, T F, Yü
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Urinary tract stones were known in prehistoric times. The oldest stone was unearthed in upper Egypt, dated approximately 4800 B.C. (Shattock, 1905). Stones have been discovered from Egyptian mummies of different dynasties (Miller, 1929; Wesson, 1935; Guthrie, 1946; Sigerist, 1951; Butt, 1956).
A B, Gutman, T F, Yü
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Seminars in Nephrology, 2011
Hyperuricemia is a common complication in organ transplant recipients, with a higher incidence in kidney and heart recipients. Risk factors for post-transplant hyperuricemia include reduced glomerular filtration rate, diuretic use, cyclosporine therapy, increasing age at transplant, obesity, and metabolic syndrome, as well as the presence of ...
Fernanda Cristina, Mazali +1 more
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Hyperuricemia is a common complication in organ transplant recipients, with a higher incidence in kidney and heart recipients. Risk factors for post-transplant hyperuricemia include reduced glomerular filtration rate, diuretic use, cyclosporine therapy, increasing age at transplant, obesity, and metabolic syndrome, as well as the presence of ...
Fernanda Cristina, Mazali +1 more
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Seminars in Nephrology, 2011
A link between serum uric acid and the development of hypertension was first hypothesized in the 1870s. Although numerous epidemiologic studies in the 1980s and 1990s suggested an association, relatively little attention was paid to it until recently. Animal models have suggested a two-step pathogenesis by which uric acid initially activates the renin ...
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A link between serum uric acid and the development of hypertension was first hypothesized in the 1870s. Although numerous epidemiologic studies in the 1980s and 1990s suggested an association, relatively little attention was paid to it until recently. Animal models have suggested a two-step pathogenesis by which uric acid initially activates the renin ...
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Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia, 2015
Nephrolithiasis is a common condition in the general population. About 5-10% of all kidney stones is composed of uric acid, however the prevalence of uric acid stones significantly increases among patients with obesity, diabetes or metabolic syndrome.
Ferraro, Pietro Manuel +1 more
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Nephrolithiasis is a common condition in the general population. About 5-10% of all kidney stones is composed of uric acid, however the prevalence of uric acid stones significantly increases among patients with obesity, diabetes or metabolic syndrome.
Ferraro, Pietro Manuel +1 more
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Current Pharmaceutical Design, 2005
Increased levels of uric acid are associated with cardiovascular disease and the metabolic syndrome. They may predict clinical outcomes and also the onset of hypertension, though it is less clear that hyperuricaemia can be regarded as an independent risk factor given its clustering with other well-recognised factors.
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Increased levels of uric acid are associated with cardiovascular disease and the metabolic syndrome. They may predict clinical outcomes and also the onset of hypertension, though it is less clear that hyperuricaemia can be regarded as an independent risk factor given its clustering with other well-recognised factors.
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Current Hypertension Reports, 2006
Epidemiologic studies published during the past 3 years support the possible role of uric acid in the onset of essential hypertension. Data from several large, longitudinal cardiovascular disease studies indicate that elevated serum uric acid is a predictor of incident hypertension and blood pressure progression.
Daniel I, Feig +4 more
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Epidemiologic studies published during the past 3 years support the possible role of uric acid in the onset of essential hypertension. Data from several large, longitudinal cardiovascular disease studies indicate that elevated serum uric acid is a predictor of incident hypertension and blood pressure progression.
Daniel I, Feig +4 more
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Current Opinion in Nephrology and Hypertension, 2003
The goal of this article is to review the physiology and describe newly defined molecular mechanisms that are responsible for renal urate transport.Four complementary DNAs have recently been cloned whose expressed proteins transport urate. Two of these proteins have been localized to the apical membrane of proximal tubular cells: one, a urate ...
Mohammed A, Rafey +3 more
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The goal of this article is to review the physiology and describe newly defined molecular mechanisms that are responsible for renal urate transport.Four complementary DNAs have recently been cloned whose expressed proteins transport urate. Two of these proteins have been localized to the apical membrane of proximal tubular cells: one, a urate ...
Mohammed A, Rafey +3 more
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Seminars in Nephrology, 2005
Increased uric acid level is a key clinical feature of preeclampsia; higher levels correlate with significant maternal and fetal morbidity and mortality. The cause of hyperuricemia and its specific role in the pathogenesis of preeclampsia, however, remain unclear.
Chun, Lam +3 more
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Increased uric acid level is a key clinical feature of preeclampsia; higher levels correlate with significant maternal and fetal morbidity and mortality. The cause of hyperuricemia and its specific role in the pathogenesis of preeclampsia, however, remain unclear.
Chun, Lam +3 more
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Uric Acid Metabolism and Uric Acid Stones
2010Uric acid nephrolithiasis comprises 8–10% of patients with kidney stone disease. However, this prevalence is higher in particular ethnic populations and in certain regions of the world. The major pathophysiologic mechanism for uric acid nephrolithiasis is unduly acidic urine.
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Dissolution enthalpies of uric acid and uric acid dihydrate
Thermochimica Acta, 2000The dissolution enthalpies of uric acid and its dihydrate in Tris-buffer solutions were measured calorimetrically for the first time. It was found that these quantities do not depend significantly on pH (7.2-8.9), temperature (t=25-37°C), ionic strength (I=0.010-0.045 mol dm-3) and uric acid concentration (c=3.4-8.5 mmol dm-3).
Wang, Z. +3 more
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