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Seminars in Nephrology, 2011
A link between serum uric acid and the development of hypertension was first hypothesized in the 1870s. Although numerous epidemiologic studies in the 1980s and 1990s suggested an association, relatively little attention was paid to it until recently. Animal models have suggested a two-step pathogenesis by which uric acid initially activates the renin ...
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A link between serum uric acid and the development of hypertension was first hypothesized in the 1870s. Although numerous epidemiologic studies in the 1980s and 1990s suggested an association, relatively little attention was paid to it until recently. Animal models have suggested a two-step pathogenesis by which uric acid initially activates the renin ...
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Uric Acid Metabolism and Uric Acid Stones
2010Uric acid nephrolithiasis comprises 8–10% of patients with kidney stone disease. However, this prevalence is higher in particular ethnic populations and in certain regions of the world. The major pathophysiologic mechanism for uric acid nephrolithiasis is unduly acidic urine.
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Current Pharmaceutical Design, 2005
Increased levels of uric acid are associated with cardiovascular disease and the metabolic syndrome. They may predict clinical outcomes and also the onset of hypertension, though it is less clear that hyperuricaemia can be regarded as an independent risk factor given its clustering with other well-recognised factors.
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Increased levels of uric acid are associated with cardiovascular disease and the metabolic syndrome. They may predict clinical outcomes and also the onset of hypertension, though it is less clear that hyperuricaemia can be regarded as an independent risk factor given its clustering with other well-recognised factors.
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Quarterly Journal of Studies on Alcohol, 1973
J S, Olin, P, Devenyi, K L, Weldon
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J S, Olin, P, Devenyi, K L, Weldon
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