Results 281 to 290 of about 96,688 (309)

Inhibition of phosphoenolpyruvate: Uridine diphosphate N-acetylglucosamine enolpyruvyltransferase by uridine diphosphate N-acetylmuramyl peptides

Biochimica et Biophysica Acta (BBA) - Enzymology, 1973
Abstract Among uridine diphosphate N-acetylmuramyl peptides, UDP-N-acetylmuramic acid- l -Ala- d -Glu -meso- diaminopimelic acid and UDP-N-acetylmuramic acid- l -Ala- d -Glu -meso- diaminopimelic acid- d -Ala- d -Ala were found to inhibit the activity of phosphoenolpyruvate: uridine diphosphate N-acetylglucosamine ...
E.J.J. Lugtenberg, P.S. Venkateswaran, H. C ~ Wu   +2 more
openaire   +3 more sources

Antagonism of Uridine Diphosphate with 3-Methylisoquinoline Compounds

Journal of Pharmaceutical Sciences, 1965
The ability of four 3-methylisoquinoline compounds to antagonize the spasmogenic effect of uridine diphosphate on goldfish intestine was determined. While there was no significant difference in potency, one compound, 6-ethoxy-7-methoxy-1-(3′,4′-diethoxybenzyl)-3-methyl-isoquinoline, had a lesser effect on acetylcholine contractions and thus may be ...
Thomas J. Haley, H. Dix Christensen
openaire   +3 more sources

Some synthetic analogues of uridine diphosphate glucose

Tetrahedron, 1963
Abstract In order to investigate the mechanisms of uridine diphosphate glucose enzymic reactions, a number of analogues with modified uracyl residues were synthesized by the morpholidate method. 3-N-Methyl-uridine (I), 4-thiouridine (II), cytidine (III), 2-thiouridine (IV), iso-cytidine (V) and 6-azauridine (VI) diphosphate α- D -glucopyranoses were ...
N. K. Kochetkov, G.I. Yeliseeva, Vladimir N. Shibaev, M. A. Grachev, V.P. Demushkin, E.I. Budowsky   +5 more
openaire   +3 more sources

Histochemical demonstration of uridine diphosphate glucose dehydrogenase

Experientia, 1961
Es wird eine Methode zur histochemischen Lokalisation der Aktivitat von DPN-spezifischer UDPG-Dehydrogenase beschrieben. Das Wasserstoff ubertragende System vom reduzierten Coenzym zuN-Thiazol-substituiertem Monotetrazol (Reduktionsindikator) bestand in der endogenen Menadionreduktase.
A. G. E. Pearse, R. Hess
openaire   +3 more sources

System-dependent outcomes during the evaluation of drug candidates as inhibitors of cytochrome P450 (CYP) and uridine diphosphate glucuronosyltransferase (UGT) enzymes: human hepatocytes versus liver microsomes versus recombinant enzymes.

Drug Metabolism and Pharmacokinetics, 2010
The ability of a drug to cause clinically significant drug-drug interactions due to direct or metabolism-dependent inhibition of cytochrome P450 (CYP) can generally be predicted from in vitro studies with human liver microsomes (HLM) or recombinant CYP ...
A. Parkinson, F. Kazmi, David B. Buckley, P. Yerino, Brian W. Ogilvie, Brandy L. Paris   +5 more
semanticscholar   +1 more source

Uridine Diphosphate Galactose 4-Epimerase Deficiency

Archives of Pediatrics & Adolescent Medicine, 1980
In addition to the galactosemias associated with galactose-1-phosphate uridylyltransferase and galactokinase deficiency, uridine diphosphate (UDP) galactose 4-epimerase deficiency is a third disorder of galactose metabolism characterized by the inability to epimerize UDPgalactose and UDPglucose.
Y, Ichiba, N, Namba, H, Misumi
openaire   +3 more sources

Inhibitory effects of uridine diphosphate on udp-glucuronosyltransferase

Life Sciences, 1998
Inhibitory effects of uridine diphosphate on the enzymatic activity of UDP-glucuronosyltransferase (UGT) were investigated. Pyrimidine nucleotides such as UDP, UTP and cytidine diphosphate reduced the activity of rat purified UGT (phenol UGT) to about 10%, 48% and 46% of the control, respectively, at the same concentration as a donor substrate, UDP ...
Hiroshi Yokota, Akira Yuasa, Hidetomo Iwano, Futoshi Ando   +3 more
openaire   +2 more sources

Uridine diphosphate glucose dehydrogenase of rat tissue

Biochimica et Biophysica Acta (BBA) - Enzymology, 1971
1. 1. UDP-glucose dehydrogenase (UDP-glucose:NAD+ oxidoreductase, EC 1.1.1.22) from rat liver was purified over 200-fold, and some of its properties were elucidated. 2. 2. The enzyme has a pH optimum of 8.9; the Km is 0.023 mM for UDP-glucose and 0.081 mM for NAD+. 3. 3.
I. Danishefsky, Robert J. Molz
openaire   +3 more sources

The enzymic synthesis of uridine diphosphate L-rhamnose

Biochemical and Biophysical Research Communications, 1962
Abstract It has been reported that an enzyme preparation from mung bean leaves (Phaseolus aureus) catalyzes the transfer of L-rhamnose from thymidine diphosphate (dTDP) L-rhamnose to 3-quercetin β-D-glucoside to form rutin (3-quercetin O-α-L-rhamnosyl-(1 → 6)-β-D-glucoside) ( Barber and Neufeld, 1961 ; Barber, 1962 ).
openaire   +3 more sources

Uridine diphosphate fructose and uridine diphosphate acetylgalactosamine from dahlia tubers

Biochimica et Biophysica Acta, 1963
Horacio G. Pontis, Nélida S. González
openaire   +3 more sources