Results 91 to 100 of about 60,013 (197)

A Scoping Review of the Emergence of Novel Synthetic Opioids in Australian Drug Markets: What Does This Mean for Harm Reduction Responses?

open access: yesDrug and Alcohol Review, EarlyView.
ABSTRACT Issues Rising synthetic opioid deaths in North America, and the emergence of nitazene harms has driven concern about novel synthetic opioids (NSO) in Australia. This scoping review aimed to map what is known about NSOs in Australia. Approach Scoping review of peer‐reviewed and grey literature on NSO detections and harms.
Emmanuel Mammoliti   +2 more
wiley   +1 more source

Prediction of major outcomes in patients with malignant hypertension using machine learning: A report from the West Birmingham malignant hypertension registry

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
Malignant hypertension (MHT) is a rare, severe condition with high morbidity and mortality. Using data from 385 patients in the West Birmingham MHT Registry, this study evaluated nine machine learning (ML) algorithms to predict a composite outcome of all‐cause mortality/dialysis over a median 11‐year follow‐up.
Antonios A. Argyris   +7 more
wiley   +1 more source

Volume kinetics of lactated Ringer's solution in adult horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Fluid therapy in horses is primarily empirical. Evidence‐based quantification of the disposition of intravenous (IV) crystalloids used in clinical practice could enhance the effectiveness of fluid therapy. Objectives To determine the pharmacokinetics (i.e., volume kinetics: VK) and associated haemodynamic effects of IV lactated ...
William W. Muir   +3 more
wiley   +1 more source

Endogenous Bacterial Endophthalmitis Complicating Hemodialysis Catheter‐Related Sepsis: A Case Report and Review of the Literature

open access: yesHemodialysis International, EarlyView.
ABSTRACT Background Endogenous endophthalmitis is an infrequent yet severe complication of hemodialysis catheter‐related sepsis. In this report, we present a case of endogenous bacterial endophthalmitis in a patient with hemodialysis catheter‐related sepsis.
Hui Guo   +5 more
wiley   +1 more source

Milk and plasma pharmacokinetics of single‐dose ubrogepant in healthy lactating women

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective The objectives of this study were to evaluate the safety, plasma and milk pharmacokinetics, excretion in breast milk, and the relative infant dose of ubrogepant following a single oral dose. Background Ubrogepant is a calcitonin gene‐related peptide receptor antagonist approved for the acute treatment of migraine in adults ...
Ramesh R. Boinpally   +3 more
wiley   +1 more source

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