In Vitro and Clinical Evaluation of Potential Interactions of Bemnifosbuvir with Drug Transporters
The Journal of Clinical Pharmacology, EarlyView.Abstract Bemnifosbuvir is a novel oral guanosine nucleotide prodrug candidate for the treatment of chronic hepatitis C virus infection. Potential drug–drug interactions (DDIs) of bemnifosbuvir as a substrate or perpetrator with regard to ATP‐binding cassette (ABC) and solute carrier (SLC) transporters were evaluated in vitro and in clinical studies ...
Xiao‐Jian Zhou +9 more
wiley +1 more source
BiomedicinesBackground/Objectives: We aimed to determine the proportion of bacterial etiology in pediatric acute epididymitis (AE) and to compare the predictive accuracy of C-reactive protein (CRP) and urinalysis.
Kang Liu +6 more
doaj +1 more source
A scoring model including procalcitonin, C-reactive protein, and urinalysis is superior to individual variables in detecting serious bacterial infection in children under three years old [PDF]
, 2011 D Roddy O'Donnell
openalex +1 more source
The Journal of Clinical Pharmacology, EarlyView.Abstract Posdinemab, a humanized immunoglobulin G1/κ monoclonal antibody, binds with high affinity to phosphorylated tau protein which is associated with Alzheimer's disease (AD) pathophysiology. Posdinemab reduced tau seeding in murine models and was well tolerated in Phase‐1 clinical studies.
Fangfang Wang +7 more
wiley +1 more source
European guidelines for urinalysis: a collaborative document produced by European clinical microbiologists and clinical chemists under ECLM in collaboration with ESCMID [PDF]
, 2001 Olov Aspevall +3 more
openalex +1 more source
Correlation Between CT-Based Bone Mineral Density and Kidney Stone Size and Their Association with 24-Hour Urinalysis Biometrics in Patients with Urinary Stones [PDF]
, 2021 Mohammad Ali Ganji Jameshouran +5 more
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Frontiers in PsychologyBackgroundWhen addressing antisocial behaviour among adolescents, programs based on the paradigm of positive psychology through enhancing self-efficacy have demonstrated their effectiveness in furthering the positive development of young people with a ...
Álvaro Fernández-Moreno +2 more
doaj +1 more source
Clinicopathologic and Histopathologic Renal Abnormalities in Dogs with Coccidioidomycosis. [PDF]
, 2016 BackgroundWe observed evidence of protein-losing nephropathy in some dogs with coccidioidomycosis, suggestive of immune complex glomerulonephritis (ICGN).
Mehrkens, LR, Mohr, FC, Sykes, JE
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Medicine Bulletin, EarlyView.ABSTRACT Background Ultrasound‐detected bladder debris is hypothesized to reflect urinary tract inflammation or infection, yet its clinical significance in older adults, a population with high asymptomatic urinary tract infections (UTI) rates and diagnostic challenges, remains poorly characterized.
Qian Lin +5 more
wiley +1 more source
Combined atypical primary hypoadrenocorticism and primary hypothyroidism in a dog [PDF]
, 2016 A dog with combined atypical primary hypoadrenocorticism and primary hypothyroidism is described. The dog presented with waxing and waning, vague complaints since more than a year and had been treated with several drugs without complete resolution of ...
Binst, Dominique +5 more
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