Results 41 to 50 of about 60,013 (197)

A New Automated Ultrasound Quantification of Urethral Mobility for Stress Urinary Incontinence

Journal of Ultrasound in Medicine, EarlyView.
Objectives Stress urinary incontinence (SUI) is a prevalent condition that can significantly affect quality of life. Urethral mobility is an important factor in SUI and transperineal ultrasound (TPUS) imaging can provide clear visualization of this movement; however, its quantification has been limited.
Kourosh Kalayeh, J. Brian Fowlkes, Bryan S. Sack, Jennifer LaCross, Stephanie Daignault‐Newton, Payton Schmidt, Haowei Tai, William W. Schultz, James A. Ashton‐Miller, John O. DeLancey   +9 more
wiley   +1 more source

Strawberry Gingivitis and Septal Perforation as Onset Manifestations of Granulomatosis With Polyangiitis Triggered by COVID‐19

JEADV Clinical Practice, EarlyView.
ABSTRACT Strawberry gingivitis is a rare but characteristic manifestation of granulomatosis with polyangiitis (GPA), characterized by red‐purple, swollen, granular gingiva. We report a 31‐year‐old woman who developed GPA following a mild COVID‐19 infection, presenting with fever, fatigue, facial pain, chronic sinusitis, epistaxis and strawberry ...
A. Segarra‐Ponce, Lucero Itsaí Quintana‐Romero, María José Zorrilla‐Marina, Bertha Lissette Sotelo‐García, Marisol Ramírez‐Padilla   +4 more
wiley   +1 more source

NLX‐112 Randomized Phase 2A Trial: Safety, Tolerability, Anti‐Dyskinetic, and Anti‐Parkinsonian Efficacy

Movement Disorders, EarlyView.
Abstract Background Levodopa‐induced dyskinesia (LID) in Parkinson's disease (PD) is associated with ‘false neurotransmitter’ release of dopamine from serotonin (5‐HT) neurons. NLX‐112 is a first‐in‐class, highly selective 5‐HT1A receptor agonist which counteracts LIDs in experimental PD models.
Per Svenningsson, Per Odin, Filip Bergquist, Karin Wirdefeldt, Dag Nyholm, Mattias Andréasson, Ioanna Markaki, Anders C. Johansson, Måns Jergil, Christopher Jankosky, Mark A. Varney, Fabienne Herbrecht, Steven A. Johnson, Adrian Newman‐Tancredi   +13 more
wiley   +1 more source

A pathway toward clinical translation of hyperpolarized [1,4‐13C2,2,3‐d2]fumarate as an imaging biomarker for early cellular necrosis in vivo

Magnetic Resonance in Medicine, EarlyView.
Abstract Purpose The detection of hyperpolarized carbon‐13 (HP 13C)‐fumarate conversion to 13C‐malate using 13C‐MRSI is a biomarker for early detection of cellular necrosis. Here, we describe the translation of HP 13C‐fumarate as a novel human imaging agent, including the evaluation of biocompatibility and scaling up of the hyperpolarization methods ...
Jonathan R. Birchall, Pascal Wodtke, Ashley Grimmer, Esben S. S. Hansen, Lotte B. Bertelsen, Nikolaj Bøgh, Marta Wylot, Maria J. Zamora‐Morales, Otso Arponen, Ines Horvat‐Menih, Elizabeth C. Latimer, Fung Tan, Evita Pappa, Johann Graggaber, Joseph Cheriyan, Kelly Holmes, Matthew J. Locke, Helen Sladen, Joan Boren, Mikko I. Kettunen, Anita Chhabra, Ian B. Wilkinson, Christoffer Laustsen, Kevin Brindle, Mary A. McLean, Ferdia A. Gallagher   +25 more
wiley   +1 more source

Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN II) Urinary Urgency Phenotyping Study: Methods and Baseline Urinary Symptoms by Age and Sex

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims To present the methods and baseline findings from a prospective, longitudinal cohort study of treatment seeking adults with urinary urgency (URG) with or without urgency urinary incontinence (UUI). Methods Adults seeking treatment for URG and/or UUI and controls were enrolled.
Giulia M. Ippolito, Kimberly Kenton, Catherine S. Bradley, Ting Lu, Brian Bieber, J. Quentin Clemens, Anna C. Kirby, Ziya Kirkali, Magaly Guerrero, Claire C. Yang, Karl Kreder, C. Emi Bretschneider, John Graff, Julia Nashif, James W. Griffith, H. Henry Lai, Cindy L. Amundsen, Anne P. Cameron, for the LURN Study Group   +18 more
wiley   +1 more source

Avoiding early diagnosis

Journal of General and Family Medicine, EarlyView.
Takao Wakabayashi, Goh Keng Wee, Mikinosuke Ishibashi, Yoshiki Akiyama, Naoki Kanda, Tomoyuki Watanabe   +5 more
wiley   +1 more source

Critical Appraisal of Guidelines for Daytime Urinary Incontinence in Children: Evaluation of Quality and Recommendations on Diagnostics

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims This study aimed to evaluate the quality of currently available guidelines on non‐neurogenic daytime urinary incontinence (DUI) in children and compare their content regarding the assessment of a child with DUI. Methods We conducted a systematic search for guidelines on non‐neurogenic DUI in children. A multidisciplinary team assessed the
J. Marleen Linde, Ilse Hofmeester, Martijn G. Steffens, Francis J. Kloosterman‐Eijgenraam, Rien J. M. Nijman, Marco H. Blanker   +5 more
wiley   +1 more source

Transurethral Fulguration of Hunner Lesion Was Effective for Primary Management of Pelvic Pain in Patients With Interstitial Cystitis: A Long‐Term Follow‐Up Study

Neurourology and Urodynamics, EarlyView.
ABSTRACT Objective This study aimed to analyze the outcomes of clinical management of patients with interstitial cystitis (IC). Patients and Methods We retrospectively analyzed the electronic medical records of patients with IC who visited outpatient clinics with pelvic pain between October 2005 and December 2019.
Hyun Ju Jeong, Yu Jin Kang, Min Soo Choo, Seong Jin Jeong, Seung‐June Oh   +4 more
wiley   +1 more source

Evaluation of Pediatric and Young Adult Cancer Survivors at Risk of Long‐Term Kidney Complications

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nephrotoxic chemotherapy, nephrectomy, abdominal radiotherapy exposure, and the presence of kidney or pelvic tumors are risk factors associated with long‐term kidney complications. This study aimed to determine the prevalence of long‐term kidney complications in patients who survived pediatric and young adult cancer and were exposed
Ahmed Zeid, Sara Delap, Claudia Mosquera Vasquez, Randal S. Olshefski, Joseph R. Stanek, Lory Guthrie, Diana Zepeda‐Orozco   +6 more
wiley   +1 more source

Prognostic value of contrast‐enhanced ultrasound in dogs with acute renal injury treated with haemodialysis

Veterinary Record, Volume 196, Issue 6, 15/22 March 2025.
Abstract Background It is clinically relevant to predict outcomes in dogs with acute kidney injury (AKI) treated with haemodialysis. The aim of this study was to evaluate the prognostic value of contrast‐enhanced ultrasound (CEUS) and its role in discriminating between AKI and acute impairment associated with chronic kidney disease (AKI/CKD).
Caterina Puccinelli, Ilaria Lippi, Tina Pelligra, Simonetta Citi   +3 more
wiley   +1 more source