Results 261 to 270 of about 1,314,589 (342)

The Expanding Role of Gene Sequencing in Shaping Fetal Therapies: Clinical and Ethical Considerations

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear   +7 more
wiley   +1 more source

NONO‐Related Syndromic X‐Linked Developmental Disability 34: Further Clinical and Molecular Delineation in a Prenatal Cohort

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective To characterize the prenatal sonographic features across different trimesters and genomic spectrum of NONO‐related X‐linked intellectual developmental disorder. Method We analyzed two fetuses presenting with corpus callosum agenesis and rare cardiac anomalies using genome sequencing and exome sequencing.
Yilin Zhao   +13 more
wiley   +1 more source

Migrasomes, Matrix‐Bound Nanovesicles, and More: Messengers in the Matrix

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) and particles (EPs) are diverse micro‐ and nanoparticles that circulate in bodily fluids and can attach to, or be deposited onto, the extracellular matrix (ECM) and other surfaces. To date, the nomenclature and classification of matrix‐bound or matrix‐associated EVs and EPs (MEVPs) have been unclear, largely due to
Anna V. Kolesov   +3 more
wiley   +1 more source

Lymphoepithelioma-Like Carcinoma of the Urinary Bladder: A Case Report. [PDF]

open access: yesCureus
Alqurashi NM   +4 more
europepmc   +1 more source

Differential regulation of bladder pain and voiding function by sensory afferent populations revealed by selective optogenetic activation [PDF]

open access: yes, 2010
DeBerry, Jennifer J   +7 more
core   +1 more source

Chiropractic spinal manipulative therapy versus physical therapist‐led exercise and the risk of cauda equina syndrome in adults with lumbar disc herniation, stenosis, or radiculopathy

open access: yesPM&R, EarlyView.
Abstract Background Cauda equina syndrome is a surgical emergency often caused by lumbar disc herniation. Spinal manipulative therapy is commonly used for lumbar spine disorders, but case reports have raised concerns it may precipitate cauda equina syndrome. One cohort study suggested no increased risk, although it did not focus on patients with lumbar
Robert J. Trager   +3 more
wiley   +1 more source

Core stability in women with and without chronic pelvic pain

open access: yesPM&R, EarlyView.
Abstract Background Physical activity (PA) and core stability levels are unknown for women with musculoskeletal chronic pelvic pain (CPP) compared to healthy women. At this time, there is no validated treatment method aimed specifically at CPP. Objective To elucidate the PA habits and core stability of women with and without CPP.
Hannah V. Chatwin   +5 more
wiley   +1 more source

Connexins 43 and 45 hemichannels mediate ATP release in the urinary bladder. [PDF]

open access: yesBladder (San Franc)
Sana-Ur-Rehman H   +5 more
europepmc   +1 more source

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