Results 71 to 80 of about 2,596,680 (296)

Renal Clearable Luminogenic Reporter for Ultrasensitive Influenza Virus Imaging and Efficient Antiviral Therapies Monitoring in Living Mice

Advanced Science, EarlyView.
A viral luminogenic reporter with chemiluminescence/fluorescence dual‐response and efficient renal clearance was developed for non‐invasive imaging and urinalysis of H1N1 virus protease, allowing for remote detection of H1N1 virus infections and monitoring of antiviral therapeutic efficacy in living mice.
Bankang Ruan, Chudan Liang, Meilin Hu, Weiping Xu, Jingjing Che, Jun Qian, Bingcai Jiang, Linna Liu, Xiancai Ma, Jiaguo Huang   +9 more
wiley   +1 more source

Urinary and bladder disturbances in Parkinson's disease

Annals of Physical and Rehabilitation Medicine, 2017
Objective To evaluate the prevalence of urinary and bladder disturbances in Parkinson's disease, specify their nature, their impact on the quality of life and their modalities of care. Material/patients and methods A prospective study including 25 patients with Parkinson's disease conducted in the neurology department of Mahdia.
Mouna Sghir, Islem Feki, Rafik Machraoui, Aymen Haj Salah, Samia Younes, Wassia Kessomtini   +5 more
openaire   +1 more source

Hodgkin's disease involving the urinary bladder diagnosed by urinary cytology. A case report [PDF]

Cancer, 1982
A unique case of lymphocyte depletion Hodgkin's disease of the urinary bladder in a 91-year-old woman was diagnosed by exfoliative cytology on a single passed urine specimen. Subsequent bladder biopsy confirmed the diagnosis. Retrospectively, it was ascertained that the patient had had a previous diagnosis of Hodgkin's disease based on biopsy of a ...
J J, Bocian, M S, Flam, C A, Mendoza
openaire   +2 more sources

UCtracker: A Deep Learning–Based DNA Methylation Model for Noninvasive Diagnosis and Recurrence Surveillance of Urothelial Carcinoma in a Prospective Study

Advanced Science, EarlyView.
We developed UCtracker, a urine DNA methylation–based deep learning model, for noninvasive diagnosis and postoperative surveillance of urothelial carcinoma. UCtracker demonstrates high diagnostic accuracy, robustness at ultralow sequencing depth, early recurrence detection, and dynamic risk‐stratified monitoring of molecular residual disease ...
Shengwei Xiong, Gaojie Li, Yucai Wu, Yuan Liang, Heng Guo, Yu Zhang, Gengyan Xiong, Long Tian, Xin Zhang, Ye Tian, Zhengguo Ji, Bin Guo, Yue Shi, Jian Fan, Zhihua Li, Yanqing Gong, Shiming He, Xuesong Li, Weimin Ci, Liqun Zhou   +19 more
wiley   +1 more source

Exploring urinary microbiome: insights into neurogenic bladder and improving management of urinary tract infections

Frontiers in Cellular and Infection Microbiology
The traditional view of sterile urine has been challenged by advancements in next-generation sequencing, revealing that the urinary microbiome significantly influences individual health and various urinary system diseases.
Jinming Zhang, Jinming Zhang, Yingyun Lei, Yingyun Lei, Huayong Du, Huayong Du, Zehui Li, Zehui Li, Xiaoxin Wang, Xiaoxin Wang, Degang Yang, Degang Yang, Feng Gao, Feng Gao, Jianjun Li, Jianjun Li   +15 more
doaj   +1 more source

Optimal management of urinary tract infections in older people [PDF]

, 2011
Urinary tract infections (UTI) occur frequently in older people. Unfortunately, UTI is commonly overdiagnosed and overtreated on the basis of nonspecific clinical signs and symptoms.
Phillips, Gabby, McMurdo, Marion E. T., Louise A Beveridge, Peter G Davey, Beveridge, Louise A., Davey, Peter G., Gabby Phillips   +6 more
core   +1 more source

Natural Product Toosendanin Suppresses the Malignant Development of Skin Melanoma by Targeting BNC2 for Degradation

Advanced Science, EarlyView.
BNC2 exhibits context‐dependent opposing functions across multiple cancer types. This study reveals BNC2 as an oncogenic driver of melanoma proliferation and metastasis through transcriptional activation of PIK3CA. The natural compound TSN simultaneously degrades BNC2 and its oncogenic partner SMAD3 via CRBN‐dependent ubiquitination.
Hui Dai, Xin Mei Zhang, Jing Cheng Zhang, Xu Ting Deng, Qiao Liu, Mustafa Hussein Ali, Fang Zhou Yin, Wu Yin   +7 more
wiley   +1 more source

[A case of Menkes disease with urinary bladder hemorrhage].

No to hattatsu = Brain and development, 2002
We report a case of Menkes disease with urinary bladder hemorrhage. Diverticulums were found at 1 year and 3 months of age. He had repetitive urinary tract infections at 2 years old and died of urinary hemorrhage at 2 years and 9 months. Large hematoma and diverticulum were found at necropsy.
Ozawa, Hiroshi, Kodama, Hiroko, Noma, Seiji, Hirayama, Aya, Ito, Masayuki, Takashima, Sachio, Hata, Junichi   +6 more
openaire   +2 more sources

Participação dos receptores CXCR2 e TRPV1 na cistite induzida por ciclofosfamida em ratos [PDF]

, 2013
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2013.A proposta do presente estudo foi avaliar a participação dos receptores CXCR2 e TRPV1 na cistite ...
Dornelles, Fabiana Noronha
core  

AARS1‐Mediated H3K27 Lactylation Rewires Glycolysis to Sustain Aggressive and Recurrent Bladder Cancer

Advanced Science, EarlyView.
AARS1 drives PI3K–AKT–mTOR‐dependent glycolysis in bladder cancer, promoting lactate accumulation, increased lactylation, H3K27la enrichment at the HK2 promoter, and HK2 transcription. HK2 reinforces glycolysis, sustaining a metabolic–epigenetic program associated with tumor progression, recurrence, and metastasis.
Qin Yuan, Tianbao Song, Yipeng He, Sihan Xia, Yaoqiu Huang, Wenlin He, Qin Yi, Zefeng Wang, Peihan Wang, Chenbo Huang, Linzhi Li, Zhen Yin, Fan Cheng, Weimin Yu   +13 more
wiley   +1 more source