Results 61 to 70 of about 2,597,035 (295)

Urinary Bladder Detrusor Dysfunction Symptoms in Lyme Disease [PDF]

International Neurourology Journal, 2013
Symptoms of urinary bladder detrusor dysfunction have been rarely reported in Lyme disease. The aim was to carry out the first systematic study to compare the prevalence of such symptoms in a group of Lyme disease patients and a group of matched controls.A questionnaire relating to detrusor function was administered to 17 serologically positive Lyme ...
Puri, BK, Shah, M, Julu, PO, Kingston, MC, Monro, JA   +4 more
openaire   +4 more sources

Urinary ATP as an indicator of infection and inflammation of the urinary tract in patients with lower urinary tract symptoms [PDF]

, 2015
BACKGROUND: Adenosine-5'-triphosphate (ATP) is a neurotransmitter and inflammatory cytokine implicated in the pathophysiology of lower urinary tract disease. ATP additionally reflects microbial biomass thus has potential as a surrogate marker of urinary
Baio, Gianluca, Malone-Lee, James, De Iorio, Maria, Sathiananamoorthy, Sanchutha, Horsley, Harry, Wildman, Scott S.P., Rohn, Jennifer L, Gill, Kiren, Khasriya, Rajvinder, Wildman, Scott, Kupelian, Anthony S   +10 more
core   +1 more source

AARS1‐Mediated H3K27 Lactylation Rewires Glycolysis to Sustain Aggressive and Recurrent Bladder Cancer

Advanced Science, EarlyView.
AARS1 drives PI3K–AKT–mTOR‐dependent glycolysis in bladder cancer, promoting lactate accumulation, increased lactylation, H3K27la enrichment at the HK2 promoter, and HK2 transcription. HK2 reinforces glycolysis, sustaining a metabolic–epigenetic program associated with tumor progression, recurrence, and metastasis.
Qin Yuan, Tianbao Song, Yipeng He, Sihan Xia, Yaoqiu Huang, Wenlin He, Qin Yi, Zefeng Wang, Peihan Wang, Chenbo Huang, Linzhi Li, Zhen Yin, Fan Cheng, Weimin Yu   +13 more
wiley   +1 more source

Urinary and bladder disturbances in Parkinson's disease

Annals of Physical and Rehabilitation Medicine, 2017
Objective To evaluate the prevalence of urinary and bladder disturbances in Parkinson's disease, specify their nature, their impact on the quality of life and their modalities of care. Material/patients and methods A prospective study including 25 patients with Parkinson's disease conducted in the neurology department of Mahdia.
Mouna Sghir, Islem Feki, Rafik Machraoui, Aymen Haj Salah, Samia Younes, Wassia Kessomtini   +5 more
openaire   +1 more source

Hodgkin's disease involving the urinary bladder diagnosed by urinary cytology. A case report [PDF]

Cancer, 1982
A unique case of lymphocyte depletion Hodgkin's disease of the urinary bladder in a 91-year-old woman was diagnosed by exfoliative cytology on a single passed urine specimen. Subsequent bladder biopsy confirmed the diagnosis. Retrospectively, it was ascertained that the patient had had a previous diagnosis of Hodgkin's disease based on biopsy of a ...
J J, Bocian, M S, Flam, C A, Mendoza
openaire   +2 more sources

Dual‐Target Nectin‐4/FAP Heterobivalent Probe 68Ga/177Lu‐FZ‐NF‐1 for Triple‐Negative Breast Cancer: Preclinical Theranostic Evaluation and First‐in‐Human Translation

Advanced Science, EarlyView.
A novel hetero‐bivalent agent, 68Ga/177Lu‐FZ‐NF‐1, concurrently targets Nectin‐4 and FAP in triple‐negative breast cancer. It yields significant preclinical tumor regression and clinically identifies additional metastatic lesions missed by 18F‐FDG PET, demonstrating promising theranostic potential for personalized management.
Ye Li, Li Sun, Xiaoyu Pan, Shuyi Lin, Dongliang Wang, Jianping Zhang, Fengshuang Qiu, Bin Zhu, Lingzhou Zhao, Fengsheng Zhang, Liyan Bai, Bingxin Gu, Xiaoping Xu, Shaoli Song   +13 more
wiley   +1 more source

Exploring urinary microbiome: insights into neurogenic bladder and improving management of urinary tract infections

Frontiers in Cellular and Infection Microbiology
The traditional view of sterile urine has been challenged by advancements in next-generation sequencing, revealing that the urinary microbiome significantly influences individual health and various urinary system diseases.
Jinming Zhang, Jinming Zhang, Yingyun Lei, Yingyun Lei, Huayong Du, Huayong Du, Zehui Li, Zehui Li, Xiaoxin Wang, Xiaoxin Wang, Degang Yang, Degang Yang, Feng Gao, Feng Gao, Jianjun Li, Jianjun Li   +15 more
doaj   +1 more source

Optimal management of urinary tract infections in older people [PDF]

, 2011
Urinary tract infections (UTI) occur frequently in older people. Unfortunately, UTI is commonly overdiagnosed and overtreated on the basis of nonspecific clinical signs and symptoms.
Phillips, Gabby, McMurdo, Marion E. T., Louise A Beveridge, Peter G Davey, Beveridge, Louise A., Davey, Peter G., Gabby Phillips   +6 more
core   +1 more source

Isocyanate‐Modified Melatplatin(IV) Enhances Antitumor Efficacy via TCF4/COL6A3‐Mediated Extracellular Matrix Remodeling and cGAS‐STING Pathway Activation in Bladder Cancer

Advanced Science, EarlyView.
A series of melatonin‐conjugated platinum(IV) prodrugs was functionalized with isocyanate chains (compounds 5‒12). MP‐12C (compound 11) was identified as the lead candidate, with optimal potency and safety. MP‐12C exhibited greater efficacy than cisplatin by increasing intracellular uptake, reshaping the extracellular matrix, activating the cGAS‐STING ...
Linhui Wang, Xiaomeng Liu, Tao Zhu, Zirun Su, Ruiping Liu, Zhe Li, Kaixuan Du, Kaipeng Jia, Chong Fu, Yuda Lin, Zihan Xue, Zhe Zhang, Chong Shen, Yunkai Qie, Zhouliang Wu, Zhiheng Liu, Kangkang Liu, Jingyuan Xu, Hailong Hu   +18 more
wiley   +1 more source

[A case of Menkes disease with urinary bladder hemorrhage].

No to hattatsu = Brain and development, 2002
We report a case of Menkes disease with urinary bladder hemorrhage. Diverticulums were found at 1 year and 3 months of age. He had repetitive urinary tract infections at 2 years old and died of urinary hemorrhage at 2 years and 9 months. Large hematoma and diverticulum were found at necropsy.
Ozawa, Hiroshi, Kodama, Hiroko, Noma, Seiji, Hirayama, Aya, Ito, Masayuki, Takashima, Sachio, Hata, Junichi   +6 more
openaire   +2 more sources