A DPP6‐Targeted PET Tracer for Non‐Invasive Imaging of Transplanted Human Islets
ABSTRACT Introduction Dipeptidyl peptidase‐like protein 6 (DPP6) is a potential molecular imaging biomarker for pancreatic and transplanted islets of Langerhans. 4hD29 is a single‐domain antibody with nanomolar affinity for DPP6. Here, we demonstrate the generation and validation of [68Ga]Ga‐NOTA‐4hD29 for Positron Emission Tomography (PET) imaging of ...
Amina Khalil +11 more
wiley +1 more source
Participação dos receptores CXCR2 e TRPV1 na cistite induzida por ciclofosfamida em ratos [PDF]
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2013.A proposta do presente estudo foi avaliar a participação dos receptores CXCR2 e TRPV1 na cistite ...
Dornelles, Fabiana Noronha
core
Summary Erysipelothrix rhusiopathiae was the causative agent of vegetative endocarditis and vertebral osteomyelitis in a 24‐year‐old Irish draught gelding that presented with prolonged history of intermittent pyrexia and tachycardia. Clinical investigations revealed persistently reduced neck mobility, tachydysrhythmia and episodic pyrexia up to 41°C ...
E. Kolovou +11 more
wiley +1 more source
Predicting Initial Trial Without Catheter Failure After Prostate Deobstruction Surgery Using Preoperative Urodynamics [PDF]
Purpose Prostate deobstruction surgery is effective for relieving lower urinary tract symptoms in men with benign prostatic obstruction, yet some patients experience failure of the initial trial without catheter (TWOC) postoperatively and require ...
Jen-Hao Kuo +7 more
doaj +1 more source
Multiscale analysis of the adult human superior hypogastric plexus and hypogastric nerve
Using tissue clearing and light‐sheet microscopy methods, we visualized the 3D mesoscopic arrangement of neural tracts, blood vessels and neurons within the adult human superior hypogastric plexus and hypogastric nerves, identifying the latter to contain thousands of neuronal cells bodies embedded along its entire length.
Kayleigh S. Scotcher +4 more
wiley +1 more source
The Dual Face of Fusobacterium nucleatum in Cancer: Foe, Friend or Both?
Fusobacterium nucleatum has established interactions with cancers in humans. However, contrary to a traditional view that these interactions are uniformly pro‐tumoural, recent evidence suggests a more nuanced role, where contact‐dependent and contact‐independent mechanisms may support either tumour progression or restriction depending on tumour site ...
Anjali Chander +3 more
wiley +1 more source
Consensus Guidelines for Diagnosis and Management of Pyruvate Dehydrogenase Complex Deficiency
ABSTRACT Primary pyruvate dehydrogenase complex deficiency (PDCD) comprises a group of monogenic disorders caused by pathogenic variants in genes encoding subunits of, or regulatory components affecting, the pyruvate dehydrogenase complex. The clinical phenotype spans a broad continuum, ranging from early onset congenital lactic acidosis to infantile ...
Nandaki Keshavan +23 more
wiley +1 more source
The menstruating bladder, an unusual cause of haematuria [PDF]
A 39 year old lady presented with flank pain and haematuria. Radiological investigations showed unilateral hydronephrosis and a serum creatinine of 102?mol/l.
DeGaetano, James +3 more
core
Gastroschisis‐Like Defect in a Crossbred Bovine Calf: Anatomical, Clinical and Surgical Perspectives
A gastroschisis‐like defect was observed in a one‐day‐old, crossbred bovine calf with evisceration of the pyloric abomasum and small intestine, likely resulting from prenatal rupture of an omphalocele. The calf presented with lethargy, hypothermia and metabolic derangements, along with elevated renal biomarkers.
Mohammad Raguib Munif +1 more
wiley +1 more source
A study of urinary catheter encrustation in patients with Proteus urinary tract infection. [PDF]
The most common cause of encrustation and blockage of long term urinary catheters is colonisation of the urinary tract by Proteus spp. However, the degree of encrustation experienced by those with Proteus colonisation differs markedly between ...
Mathur, S.
core

