Results 141 to 150 of about 230,488 (361)
A Randomized, Double‐Blind, Placebo‐Controlled Trial of Abatacept for the Treatment of Relapsing, Nonsevere Granulomatosis With Polyangiitis
Arthritis &Rheumatology, EarlyView.Objective
To compare the efficacy of abatacept to placebo for the treatment of relapsing, nonsevere granulomatosis with polyangiitis (GPA). Methods
In this multicenter trial, eligible patients with relapsing, nonsevere GPA were randomized to receive abatacept 125 mg subcutaneously once a week or placebo, both together with prednisone 30 mg/day (or ...Carol A. Langford, Nader Khalidi, Jason Springer, Marcia Friedman, Bernhard Hellmich, Christian Pagnoux, Natasha Dehghan, Ora Gewurz‐Singer, Curry L. Koening, Yih Chang Lin, Paul A. Monach, Larry W. Moreland, Aurore Fifi‐Mah, Oliver Flossmann, Lindsy J. Forbess, Peter Lanyon, Eamonn Molloy, Ulrich Specks, Robert Spiera, Elaine Yacyshyn, Carol A. McAlear, Cristina Burroughs, Rachel B. Jones, Rennie L. Rhee, Rula Hajj‐Ali, Kenneth J. Warrington, David Cuthbertson, Jeffrey P. Krischer, David Jayne, Peter A. Merkel, for the Vasculitis Clinical Research Consortium and the European Vasculitis Society, Eric Stratton, Marcin Trojanowski, Chris Zammitti, Jessica Ziemek, Javier Ache, Marianne Bernardo, Bryan Gonzalez, Mariko Ishimori, Bonnie Paul, Mahbuba Tusty, Swamy Venuturupalli, Daniel Wallace, Michael Weisman, Debora Bork, Tiffany Clark, Sonya Crook, Kathleen Gartner, Lori Strozniak, Elizabeth Kisela, Marcia Leon, Loretta Williams, Jeff Negrey, Hannah Thome, Andrew Wiecek, Beemnet Amdemicael, Emily Bakaj, Aliza Bloostein, Annel Fernandez, Chris Hatzis, Lindsay Lally, Misbah Baqir, Cynthia Beinhorn, Shannon Daley, Sue Donlinger, Samantha Fatis, Yeoniee Kim, Matthew Koslow, Matthew J. Koster, Kathleen Mieras, Tobias Peikert, Michael Stachowitz, Gwen E. Thompson, Medius Klinik Kirchheim, Nicole Hollinger, Nina Kempiners, Hartmut Mahrhofer, Anke Reichelt de Tenorio, Bastian Walz, Banita Aggarwal, Simon Carette, Nazrana Haq, Samyukta Jagadeesh, Suneet Khurana, Judy Vendramini, Amanda Butler, Mithun Chakravorty, Paige Draper, Cattleya Godsave, Marie‐Josèphe Pradère, Megan Rutter, Alan Thomas, Rebekah Alexander, Cong‐Qiu Chu, Daniela Ghetie, Amy Jeon, Michelle Jin, Kim Phung Nguyen, Brenda Olmos, Kelly Peel, Rosy Quinn, Cailin Sibley, Mayamol Joseph, Deepa Thapa, Sandra Messier, Diane Robins, Jayamarx Jayaraman, Kam Shojania, Richard Conway, Kathy Brickell, Phil Gallagher, Alison Clifford, Sylvia Gaucher, Ainslie Hildebrand, Karen Martins, Breanne Stewart, Stephen Chaudary, Namneet Sandhu, Stephen Williams, Karen Dahlsveen, Seerapani Gopaluni, Cecilia Matara, Mark McClure, Rona Smith, Amrita Bath, Leslie Glasco, Theresa Howard, Caitlin McMillian, Na Yu, Mingcai Zhang, Ruba Kado, Emily Lewis, W. Joseph McCune, Emily Siegwald, Jennifer Sylvester, Naomi Amudala, Kathryn Doyle, Matthew MacDonald, Leah Madden, Brian Rice, Antoine Sreih, Sally Thompson, Laurie Hope, Kimberly Liang, Douglas Lienesch, Niveditha Mohan, Kelly Reckley, John Carter, Gail Lewis, Michelle Orzechowski, Martha Finco, Jennifer Godina, Jessica Gonzalez, Julieanne Hall, Nereida Ortez, Gopi Penmetsa +155 morewiley +1 more sourceThe 15-year national trends of urinary cancers incidence among Iranian men and women; 2005–2020
International Journal for Equity in HealthBackground Urinary tract cancers including bladder, kidney, ureter, and pelvis are a common malignancy worldwide with high mortality ratio. Aimed to investigate the prevalence of these cancers, we conducted this study.Amir-Hossein Mousavian, Gita Shafiee, Ali Sheidaei, Narges Zargar Balajam, Mehdi Ebrahimi, Fatemeh Khatami, Kimiya Gohari, Alisam Aryan, Ali Ghanbari-Motlagh, Afshin Ostovar, Seyed Mohammad Kazem Aghamir, Ramin Heshmat +11 moredoaj +1 more sourceThe excess burden of cancer in men in the UK [PDF]
, 2009 In general men are at significantly greater risk than women from nearly all of the common cancers that occur in both sexes (with the exception of breast cancer) (White 2009, Wilkins 2006, DH 2007).FORMAN, D, THOMPSON, C, WHITE, Acore Harnessing Nature: Computational and Experimental Insights Into Ipomoea obscura Metabolites for Bladder Cancer Therapy
Chemistry &Biodiversity, EarlyView.ABSTRACT
Ipomoea obscura (L.), a medicinal plant from the Convolvulaceae family, has been traditionally used to treat various ailments. This study evaluated the in vitro cytotoxicity of its ethanolic leaf extract against human bladder cancer T24 cells and investigated its phytochemical constituents through computational methods.Saravana Prabha Poochi, Rajamanikandan Sundarraj, Manikandan Vani Raju, Meenakshi Kaniyur Chandrasekaran, Rathi Muthaiyan Ahalliya, Chella Perumal Palanisamy, Gopalakrishnan Velliyur Kanniappan, Benod Kumar Kondapavuluri, Muthu Thiruvengadam +8 morewiley +1 more sourceImpacts of Diets and Food Plans in Health and Diseases—A Narrative Review
Food Safety and Health, EarlyView.This review emphasizes different diet types, providing insights into their nutritional content and health effects. Vegetarian and vegan diets, ketogenic diets, Mediterranean diets, Western diets, pescatarian diets, flexitarian diets, and territorial diversified diets are discussed, highlighting their influences on health, and diseases.Md. Mahbubar Rahman, Manisha Pandit, Bhawana Thukral, Morshed M. Khandoker +3 morewiley +1 more sourceIs the incidence of early‐onset cancers increasing in the northeast of Italy? A 30‐year analysis of the regional cancer registration data by age, 1987–2019
International Journal of Cancer, EarlyView.Whats New?
This observational study of the incidence trends of malignancy by site, stratified by age group and sex, over three decades in a large northern Italian population reveals a heterogeneous landscape among younger adults (aged under 50). Invasive cutaneous melanoma in both sexes, testicular cancer and multiple myeloma in males, and breast ...Alessandra Buja, Chiara Trevisiol, Andrea Miatton, Stefano Guzzinati, Emanuela Bovo, Simone Mocellin, Alberto Fantin, Massimo Rugge, Vincenzo Bronte, Manuel Zorzi +9 morewiley +1 more sourceIntegrative omics approaches to uncover liquid‐based cancer‐predicting biomarkers in Lynch syndrome
International Journal of Cancer, EarlyView.What's New?
Lynch syndrome (LS) significantly increases lifetime cancer risk, necessitating innovative approaches for risk stratification. Current risk assessment methods, however, fail to integrate data from different biological systems, which may be influenced by lifestyle factors.Minta Kärkkäinen, Tero Sievänen, Tia‐Marje Korhonen, Joonas Tuomikoski, Kirsi Pylvänäinen, Sami Äyrämö, Toni T. Seppälä, Jukka‐Pekka Mecklin, Eija K. Laakkonen, Tiina Jokela +9 morewiley +1 more source