Results 151 to 160 of about 114,734 (260)

Role of human RNase 7 in neuronal and glial cell models: moving towards an unexpected new functional link

The FEBS Journal, EarlyView.
Human RNase 7 is known to exert antimicrobial activity in epithelial tissues. Here, using SH‐SY5Y and U‐87 MG, neuroblastoma and glioblastoma cell lines, respectively, we found that RNase 7 enhances immune responses to LPS stimulation by reducing the expression of pro‐inflammatory cytokines, nitric oxide, and ROS.
Rosanna Culurciello, Maria Cristiano, Ilaria Di Nardo, Ida Palumbo, Erika Piccolo, Rosario Oliva, Andrea Bosso, Aldo Donizetti, Eugenio Notomista, Elio Pizzo   +9 more
wiley   +1 more source

Clinical outcomes of BCG‐treated patients with high‐risk non‐muscle‐invasive bladder cancer according to pre‐ and post‐2021 European Association of Urology risk classifications

BJU International, EarlyView.
Tian Ye, Benjamin Tura, Ben Abbotts, Maurice P. Zeegers, K. K. Cheng, Nicholas D. James, Richard T. Bryan   +6 more
wiley   +1 more source

Marked attenuation of P63 expression in plasmacytoid urothelial carcinoma with expanded immunohistochemical framework including E‐cadherin, P120, HER2 and TRPS1

Histopathology, EarlyView.
Plasmacytoid urothelial carcinoma demonstrates marked attenuation of p63 expression together with frequent disruption of the E‐cadherin–p120 adhesion complex, supporting its characteristic discohesive growth pattern. Standardized HER2 scoring identifies a substantial positive subset, highlighting diagnostic pitfalls and potential therapeutic relevance ...
Busra Yaprak Bayrak, Kemal Kosemehmetoglu, Busra Ozbek, Sercan Simsek, Murat Oktay, Ganime Coban, Dilara Irem Arslan Kahraman, Egemen Akıncıoglu, Melek Buyukgok, Selin Colak, Hatice Nese Dogan, Burak Gurel, Selva Kabul, Kerem Karaca, Elif Ozsagir, Ece Ozturk, Havva Serap Toru, Gupse Turan, Nazif Alperen Yıldırım, Ozlem Nur Yıldız, Yasemin Yuyucu Karabulut, Liang Cheng, Mahmut Akgul   +22 more
wiley   +1 more source

Mortality trends in the co-occurrence of urinary tract cancer and diabetes mellitus. [PDF]

Front Endocrinol (Lausanne)
Ou CZ, Xiong YJ, Meng XD, Lv T, Song L.
europepmc   +1 more source

NFE2L2‐mutated urothelial carcinomas frequently show concomitant myxoid and squamous features and have high PD‐L1 expression

Histopathology, EarlyView.
Aims NFE2L2 encodes the transcription factor, NRF2, which is a regulator of cellular oxidative stress responses and metabolic homeostasis. NFE2L2 alterations are implicated in multiple cancers, with significant study in thoracic oncology, with an adverse prognosis, aggressive behaviour, metabolic reprogramming and diminished responses to chemotherapy ...
Dane Wuori, Alexander Guzzetta, Melissa Y. Tjota, Peng Wang, Tatjana Antic, Jung Woo Kwon   +5 more
wiley   +1 more source

PAX8-positive conventional urothelial carcinomas of the urinary bladder and their distinct molecular profiles - A clinicopathologic study of 101 consecutive cases with next-generation sequencing in 20 cases. [PDF]

Histopathology
Lammert SM, Luo W, Zhu AC, Wang P, Antic T, Kwon JW.   +5 more
europepmc   +1 more source

Guidance for Specialised Cancer Nursing of People With Gynaecological Cancers: A Scoping Review

Journal of Clinical Nursing, EarlyView.
ABSTRACT Background Gynaecological cancer nurses are crucial to the delivery of quality, specialised care to meet the needs of people with these cancers. The extent of evidence‐based guidance to support nursing care is unknown. Aim To identify and describe existing international guidance for specialised gynaecological cancer nursing care.
Natalie Williams, Georgia Halkett, Tracey Moroney, Sharon MacLean, Olivia Cook   +4 more
wiley   +1 more source

BSAVA Petsavers Article: Validation of an ELISA assay for measurement of the metabolite of serotonin, 5‐hydroxyindole acetic acid (5‐HIAA), in canine urine

Journal of Small Animal Practice, EarlyView.
Objectives Serotonin (5‐hydroxytryptophan), implicated in a number of canine diseases, has a very short half‐life in the serum. Urine concentration of its breakdown product 5‐hydroxyindole acetic acid after an 8 hour fast is a more reliable measure of circulating serotonin in humans.
D. Castillo, A. Swallow, T. Williams, P. Watson   +3 more
wiley   +1 more source

Leverage of quick-soluble gelatin microparticles in transarterial chemoembolization of canine urothelial carcinomas. [PDF]

Vet Q
Jeon S, Lee G, Kim JK, Lee N, Chang D.
europepmc   +1 more source

Clinical benefit of faecal microbiota transplantation administered via a single retention enema as an adjunctive treatment in dogs with chronic enteropathy: a randomised controlled trial

Journal of Small Animal Practice, EarlyView.
Objectives To evaluate the clinical benefit of faecal microbiota transplantation administered via a single retention enema, as an adjunctive treatment in the management of dogs with chronic enteropathy. Materials and Methods Blinded, randomised controlled trial.
F. Allerton, M. J. Whittle, L. Durkin, C. Prior, M. Trehy, H. Swales, F. Duplan, S. Borgonovi, G. Pinchbeck, I. Gajanayake, M. Dunning, T. Sparks, P. Watson, G. C. A. Amos, K. McCallum, J. Bazelle, A. Kent   +16 more
wiley   +1 more source