Results 31 to 40 of about 20,581 (253)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
BMC UrologyObjective To explore the clinical features of inflammatory myofibroblastic tumors (IMT) of the retroperitoneal and genitourinary system. Methods We conducted a retrospective analysis of the clinical data of 23 patients with pathologically confirmed ...
Qianhao Huang +7 more
doaj +1 more source
Bilateral Urinary Calculi [PDF]
Proceedings of the Royal Society of Medicine, 1933 Cases in which stones are found on both sides at the same time are alone considered. They form 9·4% of the admissions for stone in the upper urinary tract at St. Peter's Hospital. Figures from Continental clinics vary from 11% to 14%, while those obtained from post-mortem records are nearly 50%. Four groups of cases are considered: (1)
openaire +2 more sources
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Clinical Chemistry, 1958 Abstract During the course of this investigation we have encountered two "fakes," both of which were represented by the patients to their respective physicians as having been "passed." They showed less than 2 per cent loss on ignition and proved to be calcium-iron-aluminum silicate rocks.
H F Leifeste, Henry O Nicholas
openaire +2 more sources
Advanced ScienceThe mTOR inhibitor everolimus has been approved as a sequential or second‐line therapy for renal cell carcinoma (RCC). However, the development of drug resistance limits its clinical applications.
Yu Luo +14 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Frontiers in SurgeryObjectiveThe novel semirigid ureteroscopy with a vacuum suction device has been increasing in the treatment of urinary stones recently. This study aimed to evaluate its clinical efficacy for treating >10 mm upper ureteral stones and impacted calculus ...
Longhui Lai +22 more
doaj +1 more source