Results 121 to 130 of about 730,403 (358)

Physiologically Based Pharmacokinetic (PBPK) Model to Predict the Magnitude of Drug–Drug Interaction Between Fezolinetant and CYP1A2 Inhibitors

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Fezolinetant is a non‐hormonal, selective neurokinin 3 receptor antagonist approved in multiple countries including the United States, in Europe, and in Asia for the treatment of moderate to severe vasomotor symptoms in menopausal women. Fezolinetant is primarily metabolized by CYP1A2 and was found to be a sensitive substrate for CYP1A2 ...
Mary P. Choules   +4 more
wiley   +1 more source

Location embedding based pairwise distance learning for fine-grained diagnosis of urinary stones [PDF]

open access: yesMICCAI 2024
The precise diagnosis of urinary stones is crucial for devising effective treatment strategies. The diagnostic process, however, is often complicated by the low contrast between stones and surrounding tissues, as well as the variability in stone locations across different patients.
arxiv  

Comparison of the morbidity and mortality of cystectomy and ileal conduit urinary diversion for neurogenic lower urinary tract dysfunction according to the approach: Laparotomy, laparoscopy or robotic

open access: yesInternational journal of urology, 2016
To evaluate and compare the morbidity and mortality of cystectomy–ileal conduit urinary diversion in patients with neurogenic lower urinary tract dysfunction according to the surgical approach, and to evaluate predictive factors of early and late ...
C. Deboudt   +5 more
semanticscholar   +1 more source

A case of Crohn's disease in a patient with megacystis microcolon intestinal hypoperistalsis syndrome

open access: yesJPGN Reports, EarlyView.
ABSTRACT Megacystis microcolon intestinal hypoperistalsis syndrome (MMIHS) is a rare congenital condition resulting in symptoms of bowel and bladder pseudo‐obstruction. It carries severe morbidity and mortality; a minority of patients survive to adulthood.
Caroline Chinchilla Putzeys   +8 more
wiley   +1 more source

Law of Urination: all mammals empty their bladders over the same duration [PDF]

open access: yesarXiv, 2013
Many urological studies rely upon animal models such as rats and pigs whose urination physics and correlation to humans are poorly understood. Here we elucidate the hydrodynamics of urination across five orders of magnitude in animal mass. Using high-speed videography and flow rate measurement at Zoo Atlanta, we discover the "Law of Urination," which ...
arxiv  

Electrokinetic Manipulations Combined With Direct and Ambient Ionization Mass Spectrometry

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) is a powerful analytical technique that typically involves sample preparation and online analytical separation before MS detection. Traditional methods often face bottlenecks in sample preparation and analytical separation, despite the rapid detection capabilities of MS.
Nicholas E. Manicke   +2 more
wiley   +1 more source

Robot‐assisted approach to ‘W’‐configuration urinary diversion: a step‐by‐step technique

open access: yesBJU International, 2017
To describe a detailed step‐by‐step approach of our technique for robot‐assisted intracorporeal ‘W’‐configuration orthotopic ileal neobladder.
A. Hussein   +9 more
semanticscholar   +1 more source

Metabolic Consequences after Urinary Diversion

open access: yesFrontiers in Pediatrics, 2014
Metabolic disturbances are well-known, but sometimes neglected immediate consequences or late sequelae following urinary diversion (UD) using bowel segments.
Raimund eStein, Peter eRubenwolf
doaj   +1 more source

Transfer learning for diagnosis of congenital abnormalities of the kidney and urinary tract in children based on Ultrasound imaging data [PDF]

open access: yesarXiv, 2017
Classification of ultrasound (US) kidney images for diagnosis of congenital abnormalities of the kidney and urinary tract (CAKUT) in children is a challenging task. It is desirable to improve existing pattern classification models that are built upon conventional image features.
arxiv  

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