Results 211 to 220 of about 429,799 (233)

Crosstalk Between Parkinson's Disease and Colorectal Cancer: Genetic Mechanisms, Gut Microbiota, and Therapeutic Insights

Health Care Science, Volume 5, Issue 5, Page 495-513, October 2026.
This review elucidates the crosstalk between Parkinson's disease and colorectal cancer, driven by shared genetics (PRKN, PINK1, DJ‐1) involving oxidative stress, cell cycle regulation, and inflammation. It identifies the gut microbiota—via functional amyloids and short‐chain fatty acids (SCFAs)—as a mechanistic bridge, offering insights for dual ...
Jiacheng Ying, Zhengyuan Fang, Cheng Zhang, Xu Liu, Jianzhi Cui, Zezhi Li, Jiayin Tang   +6 more
wiley   +1 more source

Urinary microbiome dysbiosis is associated with an inflammatory environment and perturbed fatty acids metabolism in the pathogenesis of bladder cancer. [PDF]

J Transl Med
Wu C, Wei X, Huang Z, Zheng Z, Zhang W, Chen J, Hong H, Li W.   +7 more
europepmc   +1 more source

Markers of Systemic Metabolic Dysfunction in Vitiligo and Their Potential Role in Disease Pathogenesis: A Narrative Review

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Vitiligo is a chronic autoimmune disease characterized by the progressive destruction of melanocytes, resulting in depigmented skin macules. While traditionally viewed as a cutaneous disorder driven by a specific CD8+ T cell‐mediated interferon‐γ (IFN‐γ) signature, emerging research suggests that vitiligo may be a systemic condition
Federica Papaccio, Simona Scano, Barbara Bellei   +2 more
wiley   +1 more source

Urinary Microbiome Dysbiosis and Immune Dysregulations as Potential Diagnostic Indicators of Bladder Cancer. [PDF]

Cancers (Basel)
Uzelac M, Xin R, Chen T, John D, Li WT, Rajasekaran M, Ongkeko WM.   +6 more
europepmc   +1 more source

Molecular and Cellular Underpinnings of Primary Hypertension: An Integrative Mechanistic Framework

Journal of Cellular Physiology, Volume 241, Issue 10, October 2026.
ABSTRACT Hypertension is a highly prevalent clinical condition and a major contributor to global cardiovascular morbidity and mortality. Despite extensive research, its complex and multifaceted pathogenesis is yet to be fully elucidated. This paper explores the updated understanding of primary hypertension as a systemic disorder rather than an isolated
Dima Nasrallah, Alaa Abdelhamid, Omar Tluli, Yaman Al‐Haneedi, Mera Abu Hussien, Ali H. Eid   +5 more
wiley   +1 more source

Characterization of pediatric urinary microbiome at species-level resolution indicates variation due to sex, age, and urologic history. [PDF]

J Pediatr Urol
Kelly MS, Dahl EM, Jeries LM, Sysoeva TA, Karstens L.   +4 more
europepmc   +1 more source

Lactobacillus-Polydopamine System for Targeted Drug Delivery in Overactive Bladder: Evidence from Bladder Cell Spheroids, Rat Models, and Urinary Microbiome Profiling. [PDF]

Int J Nanomedicine
Wang X, Wang G, Cen P, Lan H, Guo L, Yisha Z, Gu A, Liu G, Wang Z, Liu T, Yu Q.   +10 more
europepmc   +1 more source

Metabolic syndrome and the urinary microbiome of patients undergoing percutaneous nephrolithotomy. [PDF]

Asian J Urol
Dornbier RA, Doshi CP, Desai SC, Bajic P, Van Kuiken M, Khemmani M, Farooq AV, Bresler L, Turk TMT, Wolfe AJ, Baldea KG.   +10 more
europepmc   +1 more source

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The Role of Gut, Vaginal, and Urinary Microbiome in Urinary Tract Infections: From Bench to Bedside

Diagnostics, 2021
Mario Matijašić, Mihaela Perić, Hana Čipčić Paljetak   +2 more
exaly