Evaluating the use of biobanked urine specimens for human urobiome studies [PDF]
Microbiology SpectrumCase–control studies focused on the urinary tract microbiome, or urobiome, have consistently reported significant associations with disease. However, clinical urobiome studies have typically been small, averaging ~50 patients per study.
Gary Curhan +2 more
exaly +4 more sources
Evaluating urine volume and host depletion methods to enable genome-resolved metagenomics of the urobiome [PDF]
MicrobiomeBackground The gut microbiome has emerged as a clear player in health and disease, in part by mediating host response to environment and lifestyle. The urobiome (microbiota of the urinary tract) likely functions similarly.
Vanessa L Hale
exaly +3 more sources
Renal pelvis urobiome dysbiosis is associated with postoperative systemic inflammatory response syndrome after percutaneous nephrolithotomy [PDF]
MSystemsEarly prediction and diagnosis of systemic inflammatory response syndrome (SIRS) following percutaneous nephrolithotomy (PCNL) are critical. This study aimed to investigate differences in clinical characteristics and the renal pelvis urobiome between ...
Kehua Jiang +2 more
exaly +4 more sources
Forming Consensus To Advance Urobiome Research.
MSystems, 2021 Urobiome research has the potential to advance the understanding of a wide range of diseases, including lower urinary tract symptoms and kidney disease.
Lisa Karstens +2 more
exaly +3 more sources
Urobiome composition after renal transplantation: an exploratory study [PDF]
BMC MicrobiologyBackground The urobiome of renal transplant recipients is poorly defined. The purpose of this study was to investigate whether there are characteristic changes in the urobiome between pre- to post-transplant states, at varying degrees of post-transplant ...
David Harriman +8 more
doaj +2 more sources
Urobiome composition varies with vesicoureteral reflux grade and history of febrile urinary tract infection [PDF]
Scientific ReportsVesicoureteral reflux (VUR) is a risk factor for urinary tract infection (UTI). However, data describing the urobiome in children with VUR are limited.
Theresa C. Barrett +11 more
doaj +2 more sources
Survey of the infant male urobiome and genomic analysis of Actinotignum spp.
Npj Biofilms and Microbiomes, 2023 The urinary bladder harbors a community of microbes termed the urobiome, which remains understudied. In this study, we present the urobiome of healthy infant males from samples collected by transurethral catheterization.
Viktor X Flores +2 more
exaly +2 more sources
Urobiome: In Sickness and in Health
Microorganisms, 2019 The human microbiome has been proven to contribute to the human condition, both in health and in disease. The metagenomic approach based on next-generation sequencing has challenged the dogma of urine sterility.
Karolina Kędzierska-Kapuza +2 more
exaly +3 more sources
Comparison of Urobiome and Urine pH in Women with or without Overactive Bladder Symptoms [PDF]
International Journal of Women's HealthApichaya Klaikaew,1 Pisut Pongchaikul,2 Rujira Wattanayingcharoenchai,1 Komkrit Aimjirakul,1 Orawee Chinthakanan,1 Jittima Manonai1 1Department of Obstetrics & Gynaecology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok ...
Klaikaew A +5 more
doaj +2 more sources
Methodological bias shapes the interpretation of the urinary microbiome in low-biomass systems [PDF]
Frontiers in MicrobiologyThe recognition of the urinary microbiome (urobiome) has challenged the long-standing paradigm of urinary tract sterility, revealing diverse microbial communities associated with both urinary health and disease.
Viviana Méndez-Sacta +5 more
doaj +2 more sources