Whole-Person, Urobiome-Centric Therapy for Uncomplicated Urinary Tract Infection
Antibiotics, 2022 A healthy urinary tract contains a variety of microbes resulting in a diverse urobiome. Urobiome dysbiosis, defined as an imbalance in the microbial composition in the microenvironments along the urinary tract, is found in women with uncomplicated ...
Douglas A Hanes +2 more
exaly +4 more sources
Evidence for an indigenous female mouse urobiome. [PDF]
PLoS ONEMice have been used as a valuable model for understanding pathophysiological mechanisms of urinary tract infection for almost six decades. Mice offer many advantages including genetic manipulation to test the role of genes and mechanisms, the ...
Sidra Sohail +8 more
doaj +3 more sources
Identification of Two Clusters in Renal Pelvis Urobiome of Unilateral Stone Formers Using 2bRAD-M
Microorganisms, 2023 Urolithiasis is a common urological disease with increasing incidence and a high recurrence rate, whose etiology is not fully understood. The application of sequencing and culturomics has revealed that urolithiasis is closely related to the urinary ...
Sen-Yuan Hong, Lintao Miao
exaly +4 more sources
The Role of the Urobiome in Kidney Transplantation: A Systematic Review [PDF]
Transplantation DirectBackground. The urinary microbiome, also known as the urobiome, was traditionally considered sterile. However, emerging evidence suggests its presence in the urinary tract.
Alberto Costa Silva, MD +5 more
doaj +3 more sources
Urogenital microbiome, intracellular bacterial communities, and their contribution to urinary tract infections [PDF]
Microbiology SpectrumThe urinary tract was long considered a sterile environment, but recent studies have revealed the presence of diverse microbial communities in healthy individuals collectively known as the urinary microbiome or urobiome.
Luciana Robino +11 more
doaj +4 more sources
Urobiome of patients with diabetic kidney disease in different stages is revealed by 2bRAD-M [PDF]
Journal of Translational MedicineBackground Knowledge of the urinary microbiome (urobiome) in diabetic kidney disease (DKD) remains limited. The most commonly used 16S rRNA sequencing technique can only provide bacterial identification at the genus level.
Nan Li +8 more
doaj +3 more sources
The urinary microbiome in association with diabetes and diabetic kidney disease: A systematic review. [PDF]
PLoS ONEBackgroundThe urinary microbiome, or urobiome, is a novel area of research that has been gaining attention recently, as urine was thought to be sterile for years.
Tiscar Graells +4 more
doaj +3 more sources
A comparison of male and female renal pelvis urobiome of unilateral stone formers using 2bRAD-M [PDF]
BMC MicrobiologyBackground Urolithiasis is a prevalent urological ailment characterized by increasing prevalence and recurrence rates, resulting in substantial social and economic burden.
Sen-Yuan Hong +3 more
doaj +3 more sources
Identification of urinary bacterial genes as biomarkers for non-invasive diagnosis of renal lupus [PDF]
Biomarker ResearchBackground Systemic lupus erythematosus (SLE) is a complex autoimmune disease that often affects the kidneys, causing lupus nephritis. Diagnosis of this affection currently relies on kidney biopsy, an invasive and complex procedure.
Virginia Pérez-Carrasco +13 more
doaj +3 more sources
Coliphages of the human urinary microbiota [PDF]
PLoS ONE, 2023 Due to its frequent association with urinary tract infections (UTIs), Escherichia coli is the best characterized constituent of the urinary microbiota (urobiome). However, uropathogenic E. coli is just one member of the urobiome. In addition to bacterial
Elias Crum +6 more
doaj +4 more sources