Results 41 to 50 of about 429,799 (233)

The microbiome in urological diseases

open access: yesInvestigative and Clinical Urology, 2020
Due to the rapid development of next-generation sequencing, it has become possible to obtain information on the sequences of all genes in a specific microbiome.
Kwang Woo Lee   +2 more
doaj   +1 more source

Cutaneous Burn Injury Modulates Urinary Antimicrobial Peptide Responses and the Urinary Microbiome [PDF]

open access: yes, 2017
OBJECTIVES: Characterization of urinary bacterial microbiome and antimicrobial peptides after burn injury to identify potential mechanisms leading to urinary tract infections and associated morbidities in burn patients.
Nelson, David E.   +25 more
core   +1 more source

Defining Dysbiosis in Patients with Urolithiasis

open access: yesScientific Reports, 2019
The prevalence of urinary stone disease (USD) is rapidly rising. However, the factors driving this increase are unknown. Recent microbiome studies suggest that dysbiosis may in part contribute to the increasing prevalence.
Anna Zampini   +4 more
doaj   +1 more source

Microbiome function predicts amphibian chytridiomycosis disease dynamics. [PDF]

open access: yes, 2022
BACKGROUND: The fungal pathogen Batrachochytrium dendrobatidis (Bd) threatens amphibian biodiversity and ecosystem stability worldwide. Amphibian skin microbial community structure has been linked to the clinical outcome of Bd infections, yet its overall
Hopkins, KP   +14 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Detecting Polyomaviruses in the Urinary Microbiome

open access: yes, 2021
The polyomaviruses JC virus (JCPyV) and BK virus (BKPyV) are thought to be common viruses in the human urinary tract, and prior studies estimate JCPyV infects between 20-80% of older adults and BKPyV infects between 65-90% of individuals by age 10. These
Mormando, Rita
core   +1 more source

Purple urine bag syndrome: rethinking the role of urinary and gut microbiome in the pathogenesis of urinary tract infections [PDF]

open access: yesMicrobiota in Health and Disease, 2020
The effort of the Humane Microbiome Project has led to the awareness that many districts of the human organism, like the skin, gastrointestinal tract, and genitals harbor their normal resident microbes.
S. Cicchinelli   +9 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

open access: yesAdvanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo   +14 more
wiley   +1 more source

The Association of Prostate Cancer and Urinary Tract Infections: A New Perspective of Prostate Cancer Pathogenesis

open access: yesMedicina, 2023
Background and objectives: Microbiota of the urinary tract may be associated with urinary tract malignancy, including prostate cancer. Materials and Methods: We retrospectively collected patients with newly diagnosed prostate cancer and subjects without ...
Szu-Ying Pan   +4 more
doaj   +1 more source

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