Results 211 to 220 of about 110,808 (247)

Neurogenic Bladder Dysfunction Presenting as Urinary Retention in Neuronopathic Gaucher Disease

open access: green, 2014
Erin R. McNamara   +4 more
openalex   +1 more source

Comparative Safety Profiles of Ocrelizumab and Rituximab in Multiple Sclerosis Treatment Using Real‐World Evidence

open access: yesAnnals of Neurology, EarlyView.
Objective The objective of this study was to compare the long‐term safety profiles of ocrelizumab and rituximab in persons with multiple sclerosis (MS). Methods Using retrospective data from the University of California (UC) Health System, we simulated a target clinical trial. The primary cohort from UC San Francisco (UCSF) and a validation cohort from
Gabriel Cerono   +3 more
wiley   +1 more source

Skeletal Muscle Biomarkers of Amyotrophic Lateral Sclerosis: A Large‐Scale, Multi‐Cohort Proteomic Study

open access: yesAnnals of Neurology, EarlyView.
Objective Biomarkers with clear contexts of use are important tools for amyotrophic lateral sclerosis (ALS) therapy development. Understanding their longitudinal trajectory in the untreated state is key to their use as potential markers of pharmacodynamic response.
Oleksandr Dergai   +16 more
wiley   +1 more source

A Novel Transcriptional Slippage Mechanism Rescues Dystrophin Expression from a DMD Frameshift Variant

open access: yesAnnals of Neurology, EarlyView.
Pathogenic DMD variants usually follow the reading‐frame rule: out‐of‐frame changes cause Duchenne muscular dystrophy, whereas in‐frame ones produce Becker muscular dystrophy (BMD). We report a 23‐year‐old man with BMD‐like weakness, calf hypertrophy, elevated creatine kinase, and dilated cardiomyopathy.
Hiroya Naruse   +16 more
wiley   +1 more source

Superhydrophilic FeIV2MnII Nanocluster: A Combined Diagnostic and Therapeutic Agent

open access: yesAngewandte Chemie, EarlyView.
An atomically precise nanocluster with a superhydrophilic architecture acts as an efficient magnetic resonance imaging (MRI) and photoacoustic imaging (PAI) dual‐mode diagnostic agent, while providing for a photothermal‐based antitumor effect. Abstract We report here an atomically precise nanocluster, (NH4)2MnII(H2O)2[FeIV(L)]2·11H2O (Fe2Mn).
Ye Xu   +9 more
wiley   +2 more sources

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