Results 111 to 120 of about 1,744,557 (311)

A Sirtuin‐1‐Targeted Gene‐Activating Tetrahedral DNA Attenuates Bladder Fibrosis by Restoring Mitophagy in Fibroblasts via the SIRT1‐FOXO3‐BNIP3 Axis

Advanced Science, EarlyView.
The SIRT1‐targeted saRNA‐delivering tetrahedral DNA (TSA) treatment effectively upregulates SIRT1 expression, which subsequently promotes FOXO3A deacetylation. This deacetylation event relieves FOXO3A's transcriptional repression on the BNIP3 gene, thereby initiating PINK1‐PARKIN‐dependent mitophagy.
Wei Wang, Ran Yan, Lede Lin, Lei Xiang, Xiaozhi Xia, Liao Peng, Xiaoshuai Gao, Jiawei Chen, Yang Xiong, Liang Zhou, Yunfeng Lin   +10 more
wiley   +1 more source

Effect of orchiectomy and testosterone replacement on lower urinary tract function in anesthetized rats [PDF]

, 2016
Chen‐Li Cheng, William C. de Groat
openalex   +1 more source

Impact of Low Preoperative Prognostic Immune Nutritional Index on Survival and Postoperative Infectious Complications in Patients With Colorectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim The prognostic immune nutritional index (PINI) is increasingly recognized for its potential clinical utility. However, multifaceted evaluations of its ability to predict oncological outcomes in colorectal cancer (CRC) and its association with postoperative infectious complications remain limited.
Shinji Yamashita, Yoshinaga Okugawa, Hiroki Imaoka, Tadanobu Shimura, Takahito Kitajima, Mikio Kawamura, Yoshiki Okita, Masaki Ohi, Minako Kobayashi, Yuji Toiyama   +9 more
wiley   +1 more source

Risk Factors for Anastomotic Stricture and Obstructive Symptoms Following Double‐Flap Technique Reconstruction After Proximal Gastrectomy

Annals of Gastroenterological Surgery, EarlyView.
This retrospective study investigated risk factors for anastomotic stricture and obstructive symptoms following double‐flap technique (DFT) reconstruction after proximal gastrectomy. Mucosal detachment, potentially caused by thermal damage, was identified as a significant risk factor for anastomotic stricture, while continuous suturing at the esophago ...
Shinji Kuroda, Yoshihiko Kakiuchi, Satoru Kikuchi, Hajime Kashima, Nobuhiko Kanaya, Shunya Hanzawa, Kenjiro Kumano, Masahiko Nishizaki, Shunsuke Kagawa, Toshiyoshi Fujiwara   +9 more
wiley   +1 more source

Protocol for a prospective, randomized study on neurophysiological assessment of lower urinary tract function in a healthy cohort [PDF]

, 2016
Stéphanie van der Lely, Martina Stefanovic, Melanie R. Schmidhalter, Marta Pittavino, Reinhard Furrer, Martina D. Liechti, Martin Schubert, Thomas M. Kessler, Ulrich Mehnert   +8 more
openalex   +1 more source

Design, Control, and Clinical Applications of Magnetic Actuation Systems: Challenges and Opportunities

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This review aims to provide a broad understanding for interdisciplinary researchers in engineering and clinical applications. It addresses the development and control of magnetic actuation systems (MASs) in clinical surgeries and their revolutionary effects in multiple clinical applications.
Yingxin Huo, Lidong Yang, Tiantian Xu, Dong Sun   +3 more
wiley   +1 more source

Ultra‐Efficient Kidney Stone Fragment Removal via Spinner‐Induced Synergistic Circulation and Spiral Flow

Advanced Intelligent Systems, EarlyView.
Leveraging spinning‐induced localized suction, the spinner device enables ultra‐efficient removal of kidney stone fragments, capturing a larger quantity of fragments from distances exceeding 20 mm. The spinner significantly improves the efficiency and effectiveness of stone fragment removal by reducing operative time, increasing stone‐free rates, and ...
Yilong Chang, Jasmine Guadalupe Vallejo, Yangqing Sun, Ruike Renee Zhao   +3 more
wiley   +1 more source

Prevalence and Antimicrobial Susceptibility Pattern of Pathogens Isolated from Different Age Groups with Urinary Tract Infection at Tangail, Bangladesh

, 2022
Mohammad Z. Abedin, Farjana Akter Koly, Md. Babul Aktar, Muhammad Irfanul Islam, Md. Anisur Rahaman, Md. Easin Arfat, Noor-E-Kashif Farnaz, Md. Oyes Quruni, Sajjad Hossen Chowdhury, Rubait Hasan, Jamiatul Husna Shathi, Abdullah Aktar Ahmed   +11 more
openalex   +1 more source

Mortality Patterns and Phenotypic Clusters in Trisomy 13: A Population‐Based Study From Japan

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Trisomy 13, the third most common autosomal trisomy after trisomy 21 and trisomy 18, is associated with a significantly high infant mortality rate. However, large‐scale studies examining causes of death in trisomy 13 remain scarce. Therefore, we aimed to better understand the mortality patterns.
Narumi Kato, Naho Morisaki, Akinori Moriichi   +2 more
wiley   +1 more source

Chemical Synthesis of Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii Capsular Polysaccharide Fragments as Leads for Cross‐Protection

Angewandte Chemie, EarlyView.
A total of 16 chemically synthesized capsular polysaccharide (CPS) fragments related to Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii were analyzed by glycan microarray. Comparative screening revealed three conserved epitopes that act as cross‐protective vaccine lead candidates against multidrug‐resistant (MDR) bacterial ...
Amar Kumar Mishra, Emelie E. Reuber, Diksha Rai, Leif E. Sander, Julia Duerr, Simon Y. Graeber, Marcus A. Mall, Bettina C. Fries, Peter H. Seeberger, Suvarn S. Kulkarni   +9 more
wiley   +2 more sources