Animal Models and Experimental Medicine, EarlyView.To address the limitations of existing models, this study innovatively established a mouse model of endometriosis (EMs) capable of mimicking cyclic bleeding. Our results confirmed that this model recapitulates the complete pathological progression from ectopic lesion establishment to systemic responses, exhibiting superior clinical relevance compared ...
Yu Zhuang +7 more
wiley +1 more source
Relative circadian disruption in urinary excretion associates with renal function in biopsy-proven primary glomerular diseases: a cross-sectional study using the novel CRDI metric. [PDF]
Ren FailWang J, Li Y, Xu X, Cai G.
europepmc +1 more source
Advances and perspectives in animal models of human hepatitis A virus
Animal Models and Experimental Medicine, EarlyView.Following HAV infection, humans, non‐human primates, and Ifnar1−/− mice develop characteristic manifestations of hepatitis A, including fecal viral shedding, elevated serum ALT levels, and inflammatory cell infiltration in the liver. In contrast, HAV‐infected human liver chimeric mice exhibit fecal viral shedding but do not develop clinical features of
Jian Li +3 more
wiley +1 more source
Angewandte Chemie, EarlyView.We present a bioluminescent diagnostic platform that integrates DNA amplification and detection in a single step. The engineering of thermostable luciferase‐intercalating dye conjugates and controlled release of caged luciferin substrates enable real‐time, detection of attomolar concentrations of viral DNA within 30 min.
Yosta de Stigter +8 more
wiley +2 more sources
Relation of Prostatic and Urinary Bladder Ultrasound Parameters in Patients With Benign Prostatic Hyperplasia. [PDF]
Health Sci RepPokharel BP +4 more
europepmc +1 more source
Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
Advanced NanoBiomed Research, EarlyView.This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source
Correction to: Therapeutic strategies for multi-resistant <i>Escherichia coli</i> in urinary tract infections-a cause for concern. [PDF]
JAC Antimicrob Resisteuropepmc +1 more source
Curcumin versus placebo in benign prostatic hyperplasia: a systematic review and meta-analysis. [PDF]
Eur J Clin PharmacolSantana DS +9 more
europepmc +1 more source
Natural Aging of Biomaterials in Ambient and Physiological Environments
Advanced NanoBiomed Research, EarlyView.Biomaterials used in biomedical applications can change their physical properties over time, even under ambient and physiological conditions. This review highlights key studies on the natural aging of materials ranging from soft hydrogels to metals and ceramics, emphasizing how time‐dependent changes influence function and performance.
Shuyu Zhang, Anne E. Staples
wiley +1 more source
Leverage of quick-soluble gelatin microparticles in transarterial chemoembolization of canine urothelial carcinomas. [PDF]
Vet QJeon S, Lee G, Kim JK, Lee N, Chang D.
europepmc +1 more source