British Journal of Clinical Pharmacology, EarlyView.Aim Ceftriaxone is a cephalosporin commonly used for the treatment of acute, severe infections; however, there are conflicting data on its disposition properties in children, making it a suitable case study for the evaluation of the appropriateness of extrapolation approaches based on exposure matching principles for paediatric patients and exploring ...
Daniel Valente Neves +7 more
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Review of combined intravesical and urethral botulinum neurotoxin type A injection in patients with neurogenic lower urinary tract dysfunction. [PDF]
Tzu Chi Med JLiu HH, Hsu CK, Young WL, Wu SY.
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Mechanistic models for intermittent haemodialysis and haemodiafiltration clearance
British Journal of Clinical Pharmacology, EarlyView.Haemodialysis has been used clinically for more than 70 years, but data regarding the clearance of medicines during dialysis are often based on studies with outdated, less efficient dialysers. Moreover, dialysis clearance is still frequently estimated using empirical approaches which lack mechanistic interpretability, are not readily generalizable ...
Laila Nassar +2 more
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Fetal Hydronephrosis: A Narrative Review of Diagnostic Pathways, Prognostic Markers, and Management. [PDF]
CureusBaltogianni IV +4 more
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British Journal of Clinical Pharmacology, EarlyView.Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
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Predictors of carotenoid status in New Zealand children using carotenoid reflection score: a cross-sectional study. [PDF]
Asia Pac J Clin NutrRapson J +5 more
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Biotechnology and Bioengineering, EarlyView.ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu +3 more
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Management of Persistent Storage Symptoms and Overactive Bladder in Men Diagnosed with Benign Prostatic Hyperplasia: A Narrative Review. [PDF]
Adv TherGill BC +3 more
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Exploratory clinical and urodynamic changes associated with mirabegron-containing multimodal treatment in children with non-monosymptomatic nocturnal enuresis: a retrospective real-world study. [PDF]
Front PediatrCai Z, Silang J, Ma X, Gesang D.
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BMEMat, EarlyView.LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng +4 more
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