Results 241 to 250 of about 828,533 (299)

Dynamic Profiling of Lipoteichoic Acid (LTA) and/or Lipopolysaccharide (LPS) Positive Extracellular Vesicles in Plasma as Diagnostic and Prognostic Biomarkers for Bacterial Infection

open access: yesAdvanced Science, EarlyView.
Using nano‐flow cytometry, this study analyzes the dynamic characteristics of lipoteichoic acid (LTA) and/or lipopolysaccharide (LPS) positive extracellular vesicles in the bloodstream of patients with bacterial infections, providing promising biomarkers for rapid and accurate diagnosis.
Qianqian Gao   +10 more
wiley   +1 more source

A Genetically Encoded Biosensor for Characterizing Transport and Metabolism of Glutarate

open access: yesAdvanced Science, EarlyView.
Here, a genetically encoded glutarate biosensor, Glusor, is developed based on transcriptional regulator CsiR. Glusor can quantify glutarate concentrations with good accuracy and precision. Then, the role of KgtP and YnfM are identified and characterized by using Glusor. Glusor also allows glutarate spatiotemporal resolution in live cells, facilitating
Kaiyu Gao   +12 more
wiley   +1 more source

Pink Urine Syndrome: A Rare Propofol-Associated Phenomenon in Critically Ill Patients. [PDF]

open access: yesCase Rep Crit Care
Villegas K   +5 more
europepmc   +1 more source

THE ESTIMATION OF METHIONINE IN PROTEIN HYDROLYSATES AND HUMAN URINE

open access: hybrid, 1944
Anthony A. Albanese   +2 more
openalex   +1 more source

KLK1 as an Epithelial‐Specific Brake Inhibits Colorectal Tumorigenesis by Suppressing B1R‐Mediated Fibroblast Phenotypic Transition

open access: yesAdvanced Science, EarlyView.
KLK1 downregulation disrupts the intestinal mucosal barrier and impairs kallikrein‐kinin signaling, thereby reducing Lys‐des‐Arg9‐BK production. This enhances B1R activation on ADAMDEC1⁺ fibroblasts, promoting inflammation and extracellular matrix (ECM) remodeling. The resulting iCAFs promote colorectal cancer progression, highlighting a novel KLK1‐B1R
Lisha Zhou   +14 more
wiley   +1 more source

Engineered crRNA Drives RPA‐T7‐CRISPR/Cas14a Cascade for Ultrasensitive Detection of ctDNA PIK3CA H1047R

open access: yesAdvanced Science, EarlyView.
The TIDE‐Cas14a system, an integrated RPA‐T7‐CRISPR/Cas14a cascade platform incorporating engineered crRNA mismatches, enables ultrasensitive detection of the PIK3CA H1047R mutation in breast cancer circulating tumor DNA, with a limit of detection as low as 0.01%, surpassing the sensitivity of droplet digital PCR.
Yuanyuan Yu   +19 more
wiley   +1 more source

NETs in the spotlight: exploring NETosis markers for tracking disease activity in IgA vasculitis. [PDF]

open access: yesRheumatology (Oxford)
Guliyeva V   +12 more
europepmc   +1 more source

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