Results 21 to 30 of about 99 (99)

Biofilm Control by Active Topography with Mucin Coating

Advanced Functional Materials, EarlyView.
This study reports a new antifouling strategy based on a bioinspired design. Mucin coating enhances biofilm control by active topography with beating micron‐sized pillars. Besides the mechanical force of beating pillars, the antibiofilm activities also involve biological factors since mucin coating inhibits swarming motility and c‐di‐GMP synthesis in ...
Zehui Han, Yikang Xu, Huan Gu, Teng Zhang, Dacheng Ren   +4 more
wiley   +1 more source

Biocompatibility of Water‐Dispersible Pristine Graphene and Graphene Oxide Using a Close‐to‐Human Animal Model: A Pilot Study on Swine

Advanced Healthcare Materials, EarlyView.
Graphene‐based materials are attracting considerable interest for biomedical applications. Analysis of their biocompatibility is required before their clinical translation, and swine represents an excellent close‐to‐human model. This study evaluates the toxicological and immunological impact of pristine graphene and graphene oxide through a compendium ...
Paola Nicolussi, Giovannantonio Pilo, Maria Giovanna Cancedda, Guotao Peng, Ngoc Do Quyen Chau, Alejandro De la Cadena, Renzo Vanna, Yarjan Abdul Samad, Tanweer Ahmed, Jeremia Marcellino, Giuseppe Tedde, Linda Giro, Acelya Ylmazer, Federica Loi, Gavina Carta, Loredana Secchi, Silvia Dei Giudici, Simona Macciocu, Dario Polli, Yuta Nishina, Ciriaco Ligios, Giulio Cerullo, Andrea Ferrari, Alberto Bianco, Bengt Fadeel, Giulia Franzoni, Lucia Gemma Delogu   +26 more
wiley   +1 more source

Probiotic‐Based Mineralized Living Materials to Produce Antimicrobial Yogurts

Advanced Healthcare Materials, EarlyView.
The self‐assembly and mineralization of collagen in the presence of probiotics produces hybrid living materials that hosts and protects the cells. Intra‐ and interfibrillar mineralization of collagen fibers, as occurring in bone, results, respectively, in a bulk and single‐cell protective layer of cells, that survive in simulated gastric conditions and,
Gloria B. Ramírez‐Rodríguez, Laura Sabio, Laura Cerezo‐Collado, Víctor Garcés, Jose M. Domínguez‐Vera, José M. Delgado‐López   +5 more
wiley   +1 more source

Urine‐Stable Aptamer‐Conjugated Gold Nanorods for the Early Detection of High‐Grade Bladder Cancer Residual Disease

Advanced Healthcare Materials, EarlyView.
Aptamer (A) conjugated gold nanorods (B) for the recognition of bladder cancer cells expressing the integrin α5β1 (C) and the visualization of the targeted GNRs@Chit‐Apt‐Itg by photoacoustic imaging at the surface of the orthotopic bladder cancer in the preclinical model (D).
Chiara Venegoni, Silvia Tortorella, Alessandra Caliendo, Irene Locatelli, Alessia Di Coste, Erica Locatelli, Filippo Capancioni, Emanuela Bua, Simona Camorani, Andrea Salonia, Francesco Montorsi, Jithin Jose, Marco Moschini, Laura Cerchia, Mauro Comes Franchini, Massimo Alfano   +15 more
wiley   +1 more source

An Intervertebral Disc (IVD) Regeneration Model Using Human Nucleus Pulposus Cells (iHNPCs) and Annulus Fibrosus Cells (iHAFCs)

Advanced Healthcare Materials, EarlyView.
This study investigates hTert‐immortalized human nucleus pulposus (iHNPCs) and annulus fibrosus (iHAFCs) cells for intervertebral disc (IVD) regeneration and spinal fusion models. A 3D‐printed citrate‐based scaffold loaded with BMP9‐stimulated iHAFCs and BMP2‐stimulated iHNPCs effectively promotes bone and cartilage formation, mimicking the IVD ...
Yi Zhu, Qing Liu, Chao Yu, Hui Zhang, Jiamin Zhong, Yonghui Wang, Ou Mei, Ethan Gerhard, Wulin You, Guowei Shen, Changqi Luo, Xingye Wu, Jingjing Li, Yi Shu, Ya Wen, Usman Zeb, Hue H. Luu, Michael J. Lee, Lewis L. Shi, Yang Bi, Jian Yang, Jiaming Fan, Russell R. Reid, Tong‐Chuan He, Liangyuan Wen   +24 more
wiley   +1 more source

Nano‐Topography Enhanced Topological‐Cell‐Analysis in Radiation‐Therapy

Advanced Healthcare Materials, EarlyView.
Radiotherapy, a treatment that implies exposition of cells to radiation, offers promise to treat cancer. Here, it is hypothesized that the nanoscale details of a scaffold can amplify the response of cells to radiation, measured through topological variables, providing ways to assess the efficacy of Radiotherapy treatment.
Francesca Pagliari, Maria‐Francesca Spadea, Pierre Montay‐Gruel, Anggraeini Puspitasari‐Kokko, Joao Seco, Luca Tirinato, Angelo Accardo, Francesco De Angelis, Francesco Gentile   +8 more
wiley   +1 more source

Designing for Degradation: Transient Devices Enabled by (Nano)Cellulose

Advanced Materials, EarlyView.
Recent progress in transient devices enabled by (nano)cellulosic materials is reviewed. Transiency mechanisms, advantages of nanocelluloses, and a suite of applications are discussed. A circular thinking approach coupled with life cycle assessment is applied to critically revisit the potential, advantages, and challenges of nanocellulose‐enabled ...
Lucas J. Andrew, Erlantz Lizundia, Mark J. MacLachlan   +2 more
wiley   +1 more source

Metal–Organic Framework‐Based Antimicrobial Touch Surfaces to Prevent Cross‐Contamination

Advanced Materials, EarlyView.
A MOF‐based antimicrobial door handle cover is developed. It completely inhibits the cross‐contamination of Gram‐positive bacterial species (Staphylococcus aureus, and Enterococcus faecalis), Gram‐negative bacterial species (Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter baumannii), and fungi (Candida albicans). Abstract Infection diseases
Javier Fonseca, Mary Cano‐Sarabia, Pilar Cortés, Jordi Saldo, David Montpeyó, Julia Lorenzo, Montserrat Llagostera, Inhar Imaz, Daniel Maspoch   +8 more
wiley   +1 more source

Functional Biomaterials Derived from Protein Liquid–Liquid Phase Separation and Liquid‐to‐Solid Transition

Advanced Materials, EarlyView.
Protein can undergo liquid–liquid phase separation and liquid‐to‐solid transition to form liquid condensates and solid aggregates. These phase transitions can be influenced by post‐translational modifications, mutations, and various environmental factors.
Tianchen Li, Dea Ilhamsyah, Benedict Tai, Yi Shen   +3 more
wiley   +1 more source

Hydrogel‐Impregnated Robust Interlocking Nano Connector (HiRINC) for Noninvasive Anti‐Migration of Esophageal Stent

Advanced Materials, EarlyView.
The development of hydrogel‐impregnated robust interlocking nano connector (HiRINC) aims to address stent migration by improving tissue adhesion and reducing mechanical mismatch in self‐expandable metallic stents (SEMSs). The network‐like porous layer of HiRINC enhances adhesion and energy dissipation, demonstrates through ex vivo and in vivo tests ...
Eunyoung Jeon, Song Hee Kim, Sukyoung Kim, Dae Sung Ryu, Ji Won Kim, Kayoung Kim, Do Hoon Kim, Jung‐Hoon Park, Joonseok Lee   +8 more
wiley   +1 more source