Results 81 to 90 of about 426,957 (202)

Design‐Assisted Chemometric UV Spectrophotometric Determination of Candesartan Cilexetil, Chlorthalidone and Amlodipine Using Principal Component Regression, Partial Least Squares and Genetic Algorithm‐Partial Least Squares Models

Analytical Science Advances, Volume 7, Issue 2, December 2026.
ABSTRACT This study presents a sustainable chemometric‐assisted UV spectrophotometric strategy for the simultaneous determination of candesartan cilexetil (CAN), chlorthalidone (CTL) and amlodipine (AML) in laboratory‐prepared mixtures and commercial pharmaceutical formulations.
Khanda F. M. Amin, Samar H. Elagamy, Reem H. Obaydo, Hayam M. Lotfy   +3 more
wiley   +1 more source

Urinary schistosomiasis among preschool children in a rural community near Abeokuta, Nigeria

Parasites & Vectors, 2010
Background The control of schistosomiasis in Nigeria is mainly by mass treatment with praziquantel through the school system, with an absence of any provision for pre-school children.
Ekpo Uwem F, Laja-Deile Akintunde, Oluwole Akinola S, Sam-Wobo Sammy O, Mafiana Chiedu F   +4 more
doaj   +1 more source

Predicting the Risk of Proteinuria Based on Blood Plasma Fourier‐Transform Infrared Spectroscopy and Machine Learning Algorithms From Pregnant Women and Newborns

Analytical Science Advances, Volume 7, Issue 2, December 2026.
ABSTRACT Proteinuria, defined by an abnormally elevated concentration of proteins in the urine, serves as a critical biomarker for the early detection and diagnosis of preeclampsia. Elevated proteinuria levels adversely affect both maternal and foetal health, increasing the risk of preterm birth and low birth weight.
Camila Lopes Ferreira, Sara Maria Santos Dias da Silva, Luma Martins Aleixo de Oliveira, Vitórya Carvalho Pádua de Magalhães, Simone Lima Silva, Sheila Cavalca Cortelli, Rodrigo Augusto Silva, Jaqueline Maria Brandão Rizzato, Marcelo Saito Nogueira, Luís Felipe Das Chagas e Silva de Carvalho   +9 more
wiley   +1 more source

A Biweekly GLP‐1R Agonist Designed With Drug‐Free Intervals for Enhanced Efficacy, Receptor Homeostasis and Gastrointestinal Tolerability

Diabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 11143-11177, December 2026.
ABSTRACT Aim To develop a next‐generation, longer‐acting, more‐clinical‐benefits agonist to achieve sustained efficacy with improved tolerability. Methods CT130 was designed from semaglutide. Binding affinity was validated via molecular dynamics and cellular assays.
Wei Ding, Qing Liu, Qiong Luo, Xiaojun Yao, Xingxing Fan   +4 more
wiley   +1 more source

Simple questionnaire and urine reagent strips compared to microscopy for the diagnosis of Schistosoma haematobium in a community in northern Ghana

, 2012
OBJECTIVE: To evaluate the utility of a simple questionnaire and urine reagent strip testing for the rapid diagnosis of Schistosoma haematobium in rural northern Ghana.
Bogoch, I. I., Andrews, J. R., Dadzie, Ephraim, Utzinger, J., Bogoch II, Andrews JR, Dadzie Ephraim RK, Utzinger J   +7 more
core   +1 more source

Evaluation of field recognizable morbidity indicators of Schistosoma haematobium infection among primary school children in Ghana

Russian Open Medical Journal, 2016
Aim - This study was a retrospective evaluation of morbidity indicators and the use of questionnaire in decisions that relate to Schistosoma haematobium infection control among primary school children in Ghana.
Ato Kwamena Tetteh, Joseph Otchere, Langbong Bimi, Irene Ayi   +3 more
doaj   +1 more source

Prostate Cancer Patient‐Derived Organoids (PDOs) as Functional Avatars for Antisense Oligonucleotide (ASO)‐Based Personalized Therapy

Advanced Healthcare Materials, Volume 15, Issue 41, 6 November 2026.
Prostate patient‐derived organoids (PDOs) were established from TURP and biopsy specimens with >90% success and retain key features of their tissues of origin, making them functional avatars for antisense oligonucleotide (ASO) therapy . Transfecting single cells outside the Matrigel matrix and then reconstituting organoids overcomes the 3D delivery ...
Thi Thom Tran, Thi Tu Uyen Phan, Michael Baboudjian, Quang Hieu Duong, Ines Sousa, Thi Thuy Le, Virginie Baylot, Sophie Giusiano, Laurent Daniel, Pauline Brige, Benjamin Guillet, Cyrille Bastide, Carmen Garrido, David Taïeb, Thi Khanh Le, Palma Rocchi   +15 more
wiley   +1 more source

Urinary bladder thickness, tumor antigen, and lower urinary tract symptoms in a low Schistosoma haematobium-endemic rural community of Nigeria

Urological Science, 2018
Objective: Bladder tumor antigen (BTA) is a common biomarker for urothelial carcinoma while bladder wall thickening (BWT) is a sign of urinary bladder irritation which suggests cystitis or early-stage bladder cancer pathology, most especially in the ...
Oyetunde Oyeyemi, Adekunle Adefalujo, Kolawole Ayeni, Williams Nabofa, Chinomso Nwozichi, Adeyemi Dada, Adebola Yusuf   +6 more
doaj   +1 more source

When the Antibiogram Offers Nothing Else: Ceftriaxone–Sulbactam–Disodium EDTA With Intravenous Colistin in Two Neonates With Metallo‐β‐Lactamase‐Producing Acinetobacter baumannii Meningitis

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Two neonates with metallo‐β‐lactamase‐producing Acinetobacter baumannii meningitis, resistant to every tested alternative, received ceftriaxone–sulbactam–disodium EDTA plus intravenous colistin, which, to our knowledge, represents the first reported neonatal use of this combinations. Cultures were sterilized by day 7; both survived with normal
Naini Puri, Shantanu Shubham, Syed Moiz Ahmed, Richa Joshi, Divya Mishra, Hanshmani Prasad Chaudhary   +5 more
wiley   +1 more source

Metabolic Changes During a Calorie‐Restricted, Fish‐Rich Ketogenic Diet Associated With Increased Circulating TMAO in Healthy Adults

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 6, November 2026.
A 2‐week calorie‐restricted, fish‐rich ketogenic diet increased circulating TMAO while improving selected glycemic and insulin‐related biomarkers in healthy adults. HDL cholesterol decreased, whereas oxidative stress markers remained unchanged, highlighting a complex short‐term metabolic response that should not be interpreted as evidence of causality.
Katarzyna Siedzik, Kamil Góral, Damian Flis, Maciej Jaguszewski, Robert A. Olek, Wiesław Ziółkowski   +5 more
wiley   +1 more source