Results 51 to 60 of about 13,757 (279)

Penile Cancer Disparities in Puerto Rican Men as compared to the United States Population

open access: yesInternational Brazilian Journal of Urology, 2012
PurposeThis study compares incidence and mortality of penile cancer in Puerto Rico (PR) with other racial/ethnic groups in the United States (US) and evaluates the extent in which socioeconomic position index (SEP) or its components influence incidence ...
Vivian Colón-López   +7 more
doaj   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu   +12 more
wiley   +1 more source

Symptoms and signs of urogenital cancer in primary care

open access: yesBMC Primary Care, 2023
Background Urogenital cancers are common, accounting for approximately 20% of cancer incidence globally. Cancers belonging to the same organ system often present with similar symptoms, making initial management challenging.
Knut Holtedahl   +9 more
doaj   +1 more source

The analysis of undiagnosed malignancies [PDF]

open access: yes, 2011
Among the pathology methods autopsy is also a valuable tool in evaluating diagnostic accuracy in oncology. Malignancies are undiagnosed due to the lack of some laboratory investigations, the absence of specific symptoms of cancers and the delayed ...
Franckevica, Ivanda   +3 more
core   +3 more sources

Single‐Cell and Spatial Transcriptomic Profiling of Penile Squamous Cell Carcinoma Reveals Dynamics of Tumor Differentiation and Immune Microenvironment

open access: yesAdvanced Science, EarlyView.
This study uses single‐nucleus RNA sequencing and spatial transcriptomics to investigate penile squamous cell carcinoma (PSCC). It reveals that PSCC tumor cells mimic normal penile epithelium differentiation, independent of HPV status. The Tum_1 subtype shows basal stem‐like characteristics and promotes invasiveness. HPV‐positive basal stem‐like tumors
Hongjian Song   +37 more
wiley   +1 more source

Role of new molecular approaches for the early diagnosis of bladder cancer in clinical practice [PDF]

open access: yes, 2014
There is an urgent need to improve the performance of urine cytology for the diagnosis of bladder cancer. In preliminary studies, telomerase activity evaluated by telomeric repeat amplification protocol (TRAP) assay and chromosomal aneuploidy detected ...
Bravaccini, Sara <1975>
core   +1 more source

Urban relatives ameliorate survival disparities for genitourinary cancer in rural patients

open access: yesCancer Medicine
Introduction Patients living in rural areas have worse cancer‐specific outcomes. This study examines the effect of family‐based social capital on genitourinary cancer survival.
Mouneeb Choudry   +12 more
doaj   +1 more source

The burden of disease in Spain: results from the global burden of disease study 2010 [PDF]

open access: yes, 2015
BackgroundWe herein evaluate the Spanish population¿s trends in health burden by comparing results of two Global Burden of Diseases, Injuries, and Risk Factors Studies (the GBD studies) performed 20 years apart.MethodsData is part of the GBD study for ...
Carmona, Loreto   +7 more
core   +2 more sources

Artificial Intelligence‐Guided Total Mesorectal Excision: Development of a Deep Learning Model to Identify the Pelvic Fascial Plane Anatomy

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
AI‐based segmentation of fascial planes during total mesorectal excision. Ground truth and predicted boundaries are compared for mesorectal fascia (blue), parietal pelvic fascia (red), and the holy plane (white). ABSTRACT Aim Total mesorectal excision entails dissection of the “holy plane” without damaging the mesorectal and parietal pelvic fasciae. We
Yuta Suzuki   +6 more
wiley   +1 more source

Management of bladder tumors in pregnancy: A case of tumor prolapse and avulsion during labor

open access: yesUrology Case Reports, 2021
Pregnancy presents unique obstacles to diagnosis and management of urologic disease. We present a case of a primigravid female with clot retention requiring evacuation in the operating room due to the avulsion of a bladder mass which prolapsed during ...
Kate A. Hanson   +5 more
doaj  

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