Results 91 to 100 of about 9,398,477 (354)

D-mannose: a promising support for acute urinary tract infections in women. A pilot study [PDF]

, 2016
Urinary tract infections still represent a significant bother for women and result in high costs to the health system. D-mannose is a simple sugar; it seems able to hinder bacteria adhesion to the urothelium.
BENEDETTI PANICI, PIERLUIGI, BRACCHI, CARLOTTA, COLAGIOVANNI, VANESSA, DOMENICI, LAVINIA, GIORGINI, MARGHERITA, MONTI, Marco, MUZII, LUDOVICO   +6 more
core  

The Prevalence and Implications of Polypharmacy in Individuals With Type 1 Diabetes

Clinical Pharmacology &Therapeutics, EarlyView.
Polypharmacy is increasingly recognized as a relevant issue in diabetes care, but its prevalence and clinical relevance in individuals with type 1 diabetes remain underexplored. This study aimed to determine the prevalence of polypharmacy and to identify associated clinical and psychological factors. Participants were recruited from a tertiary diabetes
Namam Ali, Stephan van Erp, Cornelis Kramers, Cornelis J. Tack, Bastiaan E. de Galan   +4 more
wiley   +1 more source

Lower Dose‐Normalized Tacrolimus Exposure in CYP3A5*6 vs. *3 Loss‐of‐Function Allele Carriers: A Longitudinal Retrospective Real‐World Study in Kidney Transplant Recipients

Clinical Pharmacology &Therapeutics, EarlyView.
Pharmacogenomic research has historically focused on individuals of European ancestry, leading to the underrepresentation of genetic variants common in non‐European populations. This bias is exemplified by CYP3A5*6, a functionally consequential variant common in individuals of African ancestry (MAF: 11–19%) but virtually absent in Europeans (MAF: 0.15%)
Amar D. Levens, Dirk Jan A. R. Moes, Yanick Boer, Aiko P. J. de Vries, Dorottya K. de Vries, Danny van der Helm, Soufian Meziyerh, Dave L. Roelen, Stefan Böhringer, Teun Van Gelder, Jesse J. Swen   +10 more
wiley   +1 more source

Urine culture and partial urinalysis in the diagnosis of urinary tract infections

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2020
Background: urinary tract infections are one of the most frequent causes of infectious disease in the medical practice.Objective: to describe the results of the sample processing of urine culture and partial urinalysis for the diagnosis of urinary tract ...
MIlagros de la Caridad Milá-Pascual, Leonor Aties-López, Ismael Torres-Milá   +2 more
doaj  

Real‐world efficacy and toxicity of ipilimumab and nivolumab as a first‐line treatment for advanced renal cell carcinoma according to IMDC risk criteria—A multi‐center retrospective analysis on behalf of the GUARDIANS group

International Journal of Cancer, EarlyView.
What's New? The combination of ipilimumab and nivolumab as a first‐line treatment for advanced renal cell carcinoma has demonstrated durable response and tolerability in clinical trials. However, inclusion criteria for clinical studies are restrictive, and patients in the real‐world setting tend to have more comorbidities.
Hendrik Dinkel, Linus Materna, Ramona Stelmach, Stefanie Zschäbitz, Stephanie Neuberger, Can D. Aydogdu, Jozefina Casuscelli, Timo Egenolf, Matteo Silberg, Julie Steinestel, Arne Strauss, Florian Kirchhoff, Marit Ahrens, Pia Paffenholz, Richard Cathomas, Berna C. Özdemir, Christopher Gossler, Philipp Ivanyi, Marc Rehlinghaus, Thomas Hilser, Viktor Grünwald, Katrin Schlack   +21 more
wiley   +1 more source

An Hsp90 co-chaperone protein in yeast is functionally replaced by site-specific posttranslational modification in humans

Nature Communications, 2017
The eukaryotic heat shock protein 90 (Hsp90) undergoes an ATP-dependent conformational cycle that is influenced by posttranslational modifications and co-chaperones.
Abbey D. Zuehlke, Michael Reidy, Coney Lin, Paul LaPointe, Sarah Alsomairy, D. Joshua Lee, Genesis M. Rivera-Marquez, Kristin Beebe, Thomas Prince, Sunmin Lee, Jane B. Trepel, Wanping Xu, Jill Johnson, Daniel Masison, Len Neckers   +14 more
doaj   +1 more source

George Higoumenakis (1895-1983): Greek dermatologist [PDF]

, 2009
This paper describes the Higoumenakis sign, enlargement of the sternal end of the clavicle in patients with late congenital syphilis and the dermatologist after whom it is named. Several professors and doctors from the Medical School of the University of
Frangos, CC, Frangos, CC
core   +1 more source

Robot‐assisted resection of diaphragmatic and hepatorenal recess peritoneal endometriosis: Two cases and a narrative review

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract In this report, we describe two cases of diaphragmatic endometriosis with concurrent hepatorenal recess peritoneal involvement managed using robotic‐assisted laparoscopic surgery with the da Vinci Xi platform. In both patients, diaphragmatic implants and hepatorenal recess peritoneal lesions were excised en bloc, followed by resection of ...
Xiaoming Guan, Qiannan Yang, Daniel Y. Lovell, Chunhua Zhang   +3 more
wiley   +1 more source

Antimicrobial resistance in pediatric patients with urinary tract infection

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2018
Background: antimicrobial resistance in pediatric patients with urinary tract infection is a growing problem, with an important medical impact. Nowadays, resistance of E.
Zunilda Leticia Bello-Fernández, Yaquelín Cozme-Rojas, Isabel Cristina Morales-Parada, Yacel Pacheco-Pérez, Maité Rua-Del-Toro   +4 more
doaj  

Chronic Colovesical Fistula Leading to Chronic Urinary Tract Infection Resulting in End-Stage Renal Disease in a Chronic Granulomatous Disease Patient

Urology Case Reports, 2017
A 46-year old man with X-linked chronic granulomatous disease (CGD) being followed at the National Institute of Health with uncontrolled CGD colitis who developed chronic colovesical fistula, and end-stage renal disease (ESRD). Despite aggressive medical
M.R. Siddiqui, T. Sanford, A. Nair, C.S. Zerbe, M.S. Hughes, L. Folio, Piyush K. Agarwal, S.J. Brancato   +7 more
doaj   +1 more source