Results 221 to 230 of about 380,997 (339)

Crucial Contribution of BACH1 to Bladder Cancer Progression via Upregulating Epithelial‐Mesenchymal Transition Pathway

Cancer Science, Volume 117, Issue 2, Page 364-376, February 2026.
BACH1 is associated with poor prognosis in BC patients and plays a critical role in promoting tumor progression and metastasis. Furthermore, we elucidated the mechanism by which BACH1 facilitates tumor progression and metastasis, primarily through activation of the EMT pathway. These findings suggest that BACH1 may serve as a novel prognostic biomarker
Tomoya Hatayama, Kenshiro Takemoto, Kohei Kobatake, Kento Miura, Liyanage P. Perera, Ryoken Yamanaka, Kazuma Yukihiro, Hiroyuki Shikuma, Kyosuke Iwane, Ryo Tasaka, Yuki Kohada, Miki Naito, Shunsuke Miyamoto, Yohei Sekino, Hiroyuki Kitano, Keisuke Goto, Akihiro Goriki, Keisuke Hieda, Osamu Kaminuma, Nobuyuki Hinata   +19 more
wiley   +1 more source

From infection to tumor: genetic evidence of viral antibody immune response' role in urologic cancer development. [PDF]

Discov Oncol
Wang C, Zhang Q, Li Q, Wang Y, Chen X.
europepmc   +1 more source

Effectiveness and Safety of Radium‐223 for Bone‐Metastatic Castration‐Resistant Prostate Cancer: The KYUCOG‐1901 Study

Cancer Science, Volume 117, Issue 2, Page 501-510, February 2026.
The KYUCOG‐1901 prospective multicenter study evaluated radium‐223 in 93 Japanese patients with bone‐metastatic castration‐resistant prostate cancer. Ra‐223 was well tolerated, produced meaningful declines in ALP, and yielded a median overall survival of 23.0 months. Early initiation in patients with lower disease burden and integration with subsequent
Masaki Shiota, Shuichi Tatarano, Tomomi Kamba, Toshiyuki Kamoto, Tsukasa Igawa, Naoya Masumori, Hirotsugu Uemura, Kensuke Mitsunari, Takayuki Sumiyoshi, Hiroji Uemura, Katsuyoshi Higashijima, Shoji Tokunaga, Masatoshi Eto   +12 more
wiley   +1 more source

Socioeconomic disparities in urological cancers in iran: a systematic analysis for the Global Burden of Disease study 2019. [PDF]

BMC Public Health
Khajavi A, Hashemi FH, Khatami F, Ortakand RK, Noori M, Rahimnia R, Aghamir SMK.   +6 more
europepmc   +1 more source

Mixed Gonadal Dysgenesis: A Comprehensive Review of Clinical Spectrum, Diagnostic Strategies, and Management Approaches

Clinical Endocrinology, Volume 104, Issue 2, Page 92-102, February 2026.
ABSTRACT Background Mixed gonadal dysgenesis (MGD) is a rare form of differences in sex development (DSD) typically associated with 45,X/46,XY mosaicism. The phenotypic presentation of MGD varies from atypical genitalia to typical male or female appearances often associated with Turner stigmata.
Dinesh Giri, Sushil Yewale, Hannah Hickingbotham, Cara Williams, Mohamed Shalaby, Julie Alderson, Julie Park   +6 more
wiley   +1 more source

A urinary DNA methylation assay using two genes enables noninvasive detection and prognostic prediction in urothelial carcinoma. [PDF]

Sci Rep
Wang D, Ai L, Tan H, Yan Y, Ye H, He M, Huang CH, Chen P, Liang Y, Wang R.   +9 more
europepmc   +1 more source

Molecular profile of atypical Leydig cell tumours

Histopathology, Volume 88, Issue 3, Page 628-635, February 2026.
Copy number variations by themselves are not sufficient to discriminate between benign and potential malignant Leydig cell tumours (LCTs). Genomic instability was only detected in malignant and atypical cases, and not in any benign tumours. Currently, the presence of metastasis remains the only malignant criterion for LCTs.
Muhammad F.K. Choudhry, Diogo Caires, Yaser Gamallat, Asli Yilmaz, Fadi Brimo, Bob Argiropoulos, Tarek A. Bismar   +6 more
wiley   +1 more source

Establishing Standardized Uptake Value Threshold for Urologic Malignancies With New Analytic Software Based on Extended Single-Photon Emission Computed Tomography-Processed Bone Scintigraphy Images. [PDF]

Cureus
Watanabe S, Motoyama D, Tamura K, Goshima S, Inamoto T.   +4 more
europepmc   +1 more source

Correlation of unfavourable and favourable histology at radical prostatectomy with Decipher scores and freedom from biochemical recurrence

Histopathology, Volume 88, Issue 3, Page 605-614, February 2026.
A recent study proposed a system of unfavourable and favourable histology categories to risk‐stratify prostate cancer patients. In a study of radical prostatectomy cases which had Decipher molecular classifier testing, unfavourable histology was associated with higher Decipher scores, increased biochemical recurrence (BCR) risk and improved BCR ...
Nancy Y Greenland, Janet E Cowan, Chien‐Kuang Cornelia Ding, Deepika Sirohi, Matthew R Cooperberg, Peter R Carroll, Jeffry P Simko, Bradley A Stohr, Li Zhang, Emily Chan   +9 more
wiley   +1 more source

Translational milestones in urologic pathology: integrating molecular diagnostics across cancer types. [PDF]

J Pathol Clin Res
Matoso A, Acosta AM.
europepmc   +1 more source