Results 41 to 50 of about 19,144 (342)

Primary signet‐ring cell carcinoma of the renal pelvis: An autopsy case

IJU Case Reports, 2022
Introduction Signet‐ring cell carcinoma is an extremely rare histological variant of upper urinary tract carcinoma, associated with poor prognosis. Case presentation We report a case of a 75‐year‐old female diagnosed with left primary upper urinary tract
Heisuke Iijima, Hiroaki Murata, Shinnosuke Oishi, Yusuke Kubota, Akihiko Sakamoto, Kuniaki Tanabe, Kazutaka Sugiyama, Akihiko Matsumoto, Ken Kuriki, Haruki Kume   +9 more
doaj   +1 more source

A Comprehensive Review of the Current State of Robot-assisted Laparoscopic Salvage Prostatectomy [PDF]

International Brazilian Journal of Urology
Background and Objective Salvage robot assisted radical prostatectomy (sRARP) is performed for patients with biochemical or biopsy proven, localized prostate cancer recurrences after radiation or ablative therapies. Traditionally, sRARP has been avoided
Parth U. Thakker, Maxwell Sandberg, Ashok K. Hemal, Alejandro R. Rodriguez   +3 more
doaj   +1 more source

Hematuria in anticoagulated patients with atrial fibrillation and urologic cancer

Research and Practice in Thrombosis and Haemostasis, 2022
Background Based on their renal excretion, direct oral anticoagulants (DOACs) may increase the risk of hematuria in patients with atrial fibrillation (AF) and urologic cancer compared with vitamin K antagonists. Objectives To examine the risk of bleeding
Anne Gulbech Ording, Mette Søgaard, Flemming Skjøth, Erik Lerkevang Grove, Gregory Y. H. Lip, Torben Bjerregaard Larsen, Peter Brønnum Nielsen   +6 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Complete en bloc urinary exenteration for synchronous multicentric transitional cell carcinoma with sarcomatoid features in a hemodialysis patient

International Brazilian Journal of Urology, 2006
The incidence of transitional cell carcinoma (TCC) in patients submitted to hemodialysis is low. The presence of TCC with sarcomatoid features in this cohort is even scarcer.
Tiberio M. Siqueira Jr, Evandro Falcao, Tiberio M. Siqueira   +2 more
doaj   +1 more source

Methotrexate‐Loaded Liposomal Formulation Enables 6‐Week Sustained Intraocular Therapeutic Drug Release in a Porcine Model

Advanced Healthcare Materials, EarlyView.
A liposomal formulation for methotrexate enables minimally invasive, sustained intraocular drug delivery for over six weeks with a single injection. Developed for treating intraocular diseases like lymphoma and PVR, it offers excellent biocompatibility in vivo in a porcine model.
Maximilian Hammer, Lea Skrzypczyk, Sabrina Wohlfart, Bryan Calder Ackermann, Ludwig Geisweid, Simon William Pohl, Margarita Karaivanova, Jonathan Herth, Victor Aristide Augustin, Alexander Studier‐Fischer, Tina Sackmann, Leon Kaulen, Anna Steyer, Walter Mier, David H Steel, Kanmin Xue, Gerd Uwe Auffarth, Philipp Uhl   +17 more
wiley   +1 more source

The role of the prostate cancer gene 3 urine test in addition to serum prostate-specific antigen level in prostate cancer screening among breast cancer, early-onset gene mutation carriers [PDF]

, 2015
Objective: To evaluate the additive value of the prostate cancer gene 3 (PCA3) urine test to serum prostate-specific antigen (PSA) in prostate cancer (PC) screening among breast cancer, early-onset gene (BRCA) mutation carriers.
Aaronson, N.K. (Neil), Ardem-Jones, A., Asperen, C.J. (Christi) van, Bancroft, E.K. (Elizabeth), Bancroft, E.K. (Elizabeth), Bangma, C.H. (Chris), Castro, E. (Elena), Cremers, R.G.H.M. (Ruben), Dearnaley, D. (David), Eccles, D. (Diana), Eeles, R. (Rosalind), Eeles, R. (Rosalind), Evans, D.G. (Gareth), Eyfjord, J., Falconer, A., Foster, C.S. (Christopher), Grönberg, H. (Henrik), Hamdy, F. (Freddie), Johansson, O., Khoo, V., Kiemeney, L.A.L.M. (Bart), Kote-Jarai, Z., Lilja, H. (Hans), Lubinski, J. (Jan), Maehle, L., Melia, J., Mikropoulos, C., Mitchell, G. (Gillian), Mitra, A. (Anita), Moss, S.M. (Sue), Moynihan, C., Page, E. (Elizabeth), Rennert, G. (Gad), Ringelberg-Borsboom, J. (Janneke), Schalken, J.A. (Jack), Suri, M. (Mohnish), Vasen, H. (Hans), Verhaegh, G. (Gerald), Wilson, P.   +38 more
core   +1 more source

A New Method of Building Patients’ Health-Awareness in Uro-Oncology

Société Internationale d’Urologie Journal, 2023
BackgroundDespite vast scientific evidence supporting health-awareness in the prevention and treatment outcome of cancer, studies comparing the effectiveness of different educational methods in in raising patients’ health-awareness are lacking ...
Pawel Nalej, Roman Sosnowski, Malgorzata Debowska, Wojciech Michalski, Tomasz Demkow   +4 more
doaj   +1 more source

ZDHHC2‐Dependent Palmitoylation Dictates Ferroptosis and Castration Sensitivity in Prostate Cancer via Controlling ACSL4 Degradation and Lipid Peroxidation

Advanced Science, EarlyView.
Our study reveals a novel mechanism by which palmitoylation regulates ferroptosis and enzalutamide resistance in prostate cancer. Under enzalutamide resistance, the FOXA1/CXXC5/TET2 complex induces aberrant upregulation of ZDHHC2, which subsequently suppresses ferroptosis by mediating S‐palmitoylation of USP19 and degradation of ACSL4 protein in CRPC ...
Shuai Shao, Wei Li, Yulong Hong, Ruijiang Zeng, Liang Zhu, Lu Yi, Yuan Li, Yinhuai Wang, Haojie Huang, Xuewen Jiang, Xin Jin   +10 more
wiley   +1 more source

Is moderate hypofractionation accepted as a new standard of care in north america for prostate cancer patients treated with external beam radiotherapy? Survey of genitourinary expert radiation oncologists [PDF]

, 2019
INTRODUCTION: Several recent randomized clinical trials have evaluated hypofractionated regimens against conventionally fractionated EBRT and shown similar effectiveness with conflicting toxicity results.
Chen, Yiyi, Degnin, Catherine, Hung, Arthur Y., McClelland, Shearwood, Mitin, Timur, Sandler, Kiri A.   +5 more
core   +1 more source