Results 51 to 60 of about 379,515 (350)

The role of the prostate cancer gene 3 urine test in addition to serum prostate-specific antigen level in prostate cancer screening among breast cancer, early-onset gene mutation carriers [PDF]

, 2015
Objective: To evaluate the additive value of the prostate cancer gene 3 (PCA3) urine test to serum prostate-specific antigen (PSA) in prostate cancer (PC) screening among breast cancer, early-onset gene (BRCA) mutation carriers.
Aaronson, N.K. (Neil), Ardem-Jones, A., Asperen, C.J. (Christi) van, Bancroft, E.K. (Elizabeth), Bancroft, E.K. (Elizabeth), Bangma, C.H. (Chris), Castro, E. (Elena), Cremers, R.G.H.M. (Ruben), Dearnaley, D. (David), Eccles, D. (Diana), Eeles, R. (Rosalind), Eeles, R. (Rosalind), Evans, D.G. (Gareth), Eyfjord, J., Falconer, A., Foster, C.S. (Christopher), Grönberg, H. (Henrik), Hamdy, F. (Freddie), Johansson, O., Khoo, V., Kiemeney, L.A.L.M. (Bart), Kote-Jarai, Z., Lilja, H. (Hans), Lubinski, J. (Jan), Maehle, L., Melia, J., Mikropoulos, C., Mitchell, G. (Gillian), Mitra, A. (Anita), Moss, S.M. (Sue), Moynihan, C., Page, E. (Elizabeth), Rennert, G. (Gad), Ringelberg-Borsboom, J. (Janneke), Schalken, J.A. (Jack), Suri, M. (Mohnish), Vasen, H. (Hans), Verhaegh, G. (Gerald), Wilson, P.   +38 more
core   +1 more source

YKT6 Promotes Bladder Cancer Progression by Stabilizing β‐catenin Through USP7‐Mediated Deubiquitination

Advanced Science, EarlyView.
The SNARE protein YKT6 is upregulated in bladder cancer (BLCA), correlating with poor prognosis. YKT6 promotes tumor proliferation and metastasis by activating Wnt/β‐catenin signaling. It recruits Ubiquitin‐Specific Peptidase 7 (USP7) to deubiquitinate and stabilize β‐catenin, enhancing its nuclear accumulation and driving oncogenic gene expression ...
Sheng Tu, Wenzhi Du, Yongwen Luo, Jiageng Shi, Tianyun Liu, Meng Ji, Kangping Xiong, Siming Chen, Fenfang Zhou, Mingxing Li, Jingtian Yu, Gang Wang, Lingao Ju, Yi Zhang, Yu Xiao, Xinghuan Wang, Kaiyu Qian   +16 more
wiley   +1 more source

A case of primary renal oncocytic tumor: Chromophobe renal cell carcinoma or oncocytoma?

IJU Case Reports, 2023
Introduction “Other oncocytic renal tumors of the kidney” is a new category constituted by 2022 WHO classification and different in the point of morphology and immunohistochemistory from typical oncocytic/eosinophilic renal tumors including chromophobe ...
Kenta Matsui, Katsunori Uchida, Masahiro Kanai, Kana Asakawa, Miki Usui, Tetsuya Murata   +5 more
doaj   +1 more source

Is moderate hypofractionation accepted as a new standard of care in north america for prostate cancer patients treated with external beam radiotherapy? Survey of genitourinary expert radiation oncologists [PDF]

, 2019
INTRODUCTION: Several recent randomized clinical trials have evaluated hypofractionated regimens against conventionally fractionated EBRT and shown similar effectiveness with conflicting toxicity results.
Chen, Yiyi, Degnin, Catherine, Hung, Arthur Y., McClelland, Shearwood, Mitin, Timur, Sandler, Kiri A.   +5 more
core   +1 more source

A Novel FGFR3‐Targeting Antibody‐Drug Conjugate Induces Tumor Cell Apoptosis through the cGAS–STING Pathway in Bladder Cancer

Advanced Science, EarlyView.
LZU‐WZLYCS01 is a novel FGFR3‐targeting ADC for bladder cancer with 7‐ethyl‐9‐fluorocamptothecin (A2) as its cytotoxic payload. LZU‐WZLYCS01 intracellularly releases A2, which targets MAD2L1 to activate the cGAS‐STING pathway and induce tumor cell apoptosis.
Shu Cui, Xiongfei Luo, Guangrui Fan, Jingqi Jiang, Yingru Wang, Enguang Yang, Jinpeng Ma, Ze Zhang, Yuhan Wang, Juan Wang, Dengtuo Wang, Hanzhang Wang, Liang Cheng, Junqiang Tian, Zhilong Dong, Yingqian Liu, Zhiping Wang   +16 more
wiley   +1 more source

High Apoptotic Index in Urine Cytology Is Associated with High-Grade Urothelial Carcinoma [PDF]

, 2016
BACKGROUND The significance of apoptosis and its association with high-grade urothelial carcinoma (HGUC) in urine cytology has yet to be determined.
Chen, Shaoxiong, Cramer, Harvey M., Wu, Howard H., Yang, Chi-Shun   +3 more
core   +1 more source

Under‐Urine‐Adhered Supramolecular Hydrogel with Linearly Sustained Quercetin Release Facilitates Hemorrhagic Cystitis Healing via Inflammation Regulation

Advanced Science, EarlyView.
A supramolecular gelatin‐based hydrogel adhesive was engineered for hemorrhagic cystitis management. It provides robust wet‐tissue adhesion, rapid hemostasis, sustained quercetin release, effectively restoring the bladder barrier via anti‐inflammatory and antioxidant actions.
Xu Cao, Hua Zhang, Yang Luo, Yaoqi Chen, Jie Yao, Renhao Ni, Tong Zhu, Yudong Yao, Jun Chen, Baolin Guo, Kerong Wu   +10 more
wiley   +1 more source

Impact of Ki-67 and E-cadherin expression on lymphovascular invasion in upper urinary tract urothelial carcinoma [PDF]

Vojnosanitetski Pregled, 2015
Bacground/Aim. Upper urinary tract urothelial carcinoma (UUT-UC) constitutes 5% of malignant neoplasms arising from transitional epithelium, but is more invasive than bladder cancer.
Stojnev Slavica, Krstić Miljan, Janković-Veličković Ljubinka, Ristić-Petrović Ana, Milojković Maja, Jovanović Ivan, Stokanović Dragana, Ugrenović Slađana   +7 more
doaj   +1 more source

Revising Fascial Anatomy With a Focus on the Fusion Fascia in Mesenteric Gastrointestinal Cancer Surgery

Annals of Gastroenterological Surgery, EarlyView.
This review critically reassesses our prior hypothesis and proposes a revised anatomical model of the fusion fascia that is broadly applicable to GI cancer surgeries grounded in the principles of mesenteric resection. Our synthesis suggests that the fusion fascia is neither a dense connective tissue membrane nor a remnant of mesothelial fusion, but ...
Hisashi Shinohara, Yasunori Kurahashi, Jun Watanabe, Yuichi Nagakawa, Tatsuro Nakamura, Eiichiro Nakao, Yudai Hojo, Shugo Kohno, Motoki Murakami, Yoshinori Ishida   +9 more
wiley   +1 more source

Surgical management for upper urinary tract transitional cell carcinoma [PDF]

, 2011
Background Upper tract transitional cell carcinomas (TCC) are uncommon and aggressive tumours. There are a number of surgical approaches to manage this condition including open radical nephroureterectomy and laparoscopic procedures.
Biyani, Chandra S., Coles, Bernadette, El-Mokadem, Ismail, Nabi, Ghulam, Rai, Bhavan Prasad, Shelley, Mike   +5 more
core   +3 more sources