Results 71 to 80 of about 389 (236)

FAM107A loss facilitates TTK‐OPTN‐mediated mitophagy to drive docetaxel resistance in castration‐resistant prostate cancer

Interdisciplinary Medicine, EarlyView.
In the progression of docetaxel resistance, downregulation of FAM107A releases its transcriptional repression of TTK, leading to TTK upregulation. TTK enhances the interaction and phosphorylation of OPTN. This activates mitophagy in tumor cells, facilitates clearance of damaged mitochondria, reduces intracellular reactive oxygen species accumulation ...
Yishan Zhang, Fan Zou, Mingdong Wang, Chenyue Wu, Yingwei Xie, Yongjun Quan, Wei Yan, Yupeng Zheng, Lianhua Li, Yuexin Liu, Jian Yu, Hao Ping   +11 more
wiley   +1 more source

Case report of seminal vesicle schwannoma with synchronous prostate cancer

Urology Case Reports
Seminal vesicle schwannomas are rare entities, reported in only a handful of cases since 2002. These benign neoplasms originate from the peripheral nerve sheath and are typically found incidentally on imaging or during the workup of nonspecific urologic ...
Mitali Kini, Joshua Cabral, Marlene Gallegos, Cristina Arruza-Frau, Safiya-Hana Belbina, Jonathan Aguiar, Vinaik Sundaresan, Gregory Raster, Faraz Longi, Larissa Bresler, Joel Cornfield   +10 more
doaj   +1 more source

Primary tubulovillous adenoma of the urinary bladder: Case report and literature review

Urological Science, 2014
Primary tubulovillous adenomas are scarcely encountered in the urinary tract, and most of these tumors arise from the intestinal segments of urinary reconstruction.
I-Hsuan Chen, Chu-Chun Chien, Chia-Cheng Yu, Tony Wu, Jong-Khing Huang   +4 more
doaj   +1 more source

Integrating Prostate‐Specific Antigen Density and Prostate Imaging Reporting and Data System Scores to Optimize Detection of Clinically Significant Prostate Cancer: A Multivariable Risk Model Approach

Journal of Clinical Laboratory Analysis, EarlyView.
For the detection of clinically significant prostate cancer, incorporating PSA density into PI‐RADS‐based assessment improved clinical net benefit compared with PI‐RADS alone. The addition of DRE and age to this combined model produced only marginal further gain, indicating that most of the incremental clinical value was derived from PSA density rather
Yunus Kayali
wiley   +1 more source

A two‐stage model for precise identification and Gleason grading of clinically significant prostate cancer: a hybrid approach

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 93-105, March 2025.
This study developed a two‐stage model using radiomics‐based multiparametric MRI and clinical indicators to help identify and grade clinically significant prostate cancer. The model showed promising levels of diagnostic accuracy and predictive performance.
Yuyan Zou, Xuechun Wang, Fen Ma, Xulun Liu, Chunyue Jiao, Zhen Kang, Jingjing Cui, Yang Zhang, Yan Xie, Lei Chen, Ronghua Tian   +10 more
wiley   +1 more source

Urinary Bladder Cancer in Yemen

Oman Medical Journal, 2013
Objectives: The aims of this study are to highlight the clinicopathological features of urinary bladder cancer in Yemen, and to describe the histological grading of urothelial neoplasms according to the World Health Organization and International Society
Abdullah Saleh Al-Samawi, Saleh Mansoor Aulaqi   +1 more
doaj   +1 more source

Effects of testosterone and high‐dose anabolic steroids on orthodontic‐induced bone remodeling and root resorption: An animal study

Journal of Periodontology, EarlyView.
Abstract Background This study investigates the impact of disruptions in testosterone levels on bone remodeling, root resorption, and periodontal ligament (PDL) during orthodontic tooth movement (OTM) in a pubertal male rat model. Methods Testosterone deficiency was induced through orchiectomy, and the anabolic‐androgenic steroid (AAS, testosterone ...
Caio Luiz Bitencourt Reis, Kelly Galisteu‐Luiz, Gabriela Leite Pedroso, Gustavo Lopes Puls, Leticia Cassaro, Bruno Boaventura Vieira, Fábio Lourenço Romano, Erika Calvano Küchler, Christian Kirschneck, Daniela Silva Barroso de Oliveira, Maria Bernadete Sasso Stuani, Mirian Aiko Nakane Matsumoto   +11 more
wiley   +1 more source

Nephrogenic adenoma of the bladder: a single institution experience assessing clinical factors

International Brazilian Journal of Urology
Introduction: Nephrogenic adenoma (NA) was first described by Davis in 1949 as a “hamartoma” of the bladder. There are many proposed predisposing factors for NA including chronic inflammation, renal transplantation, and bladder cancer.
Yooni Yi, Angela Wu, Anne P. Cameron
doaj   +1 more source

Level of Vascular Ligation for Sigmoid Colon Cancer: Does It Matter? The Pina Low‐T Study

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Methods In sigmoid colon cancer surgery, the inferior mesenteric artery (IMA) can be ligated at its origin (high ligation, HLG) or distal to the left colic artery bifurcation (low ligation, LLG). While high ligation facilitates lymph node harvest and mobilization, it may compromise colonic perfusion and increase nerve injury ...
Silvia Picotto, Elisabetta Seno, Marcello Calabrò, Massimiliano Di Marzo, Giuseppina Lo Moro, Mauro Santarelli, Paolo Delrio, Andrea Muratore   +7 more
wiley   +1 more source

A systematic review and meta-analysis on mortality rate following total pelvic exenteration in cancer patients

BMC Cancer
Background Total pelvic exenteration (TPE), an en bloc resection is an ultraradical operation for malignancies, and refers to the removal of organs inside the pelvis, including female reproductive organs, lower urological organs and involved parts of the
Arezoo Esmailzadeh, Mohammad Sadegh Fakhari, Nafise Saedi, Nasim Shokouhi, Amir Almasi-Hashiani   +4 more
doaj   +1 more source