Results 131 to 140 of about 382,165 (310)

Research Status of Androgen Deprivation Therapy Monotherapy and Combination Therapy for Prostate Cancer: A Scoping Review

Cancer Management and Research
Xiaolin Lu,1,2 Xiaojie Bian,1,2 Shanshan Wang,1,2 Dingwei Ye1,2 1Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, People’s Republic of China; 2Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, People’s
Lu X, Bian X, Wang S, Ye D
doaj  

Natural‐Inspired Engineered Microalgae With Selenium Enrichment Enabled Potent Anti‐Tumor Immunity

Advanced Science, EarlyView.
Se‐Ssp was engineered as a potent immunomodulator for activating innate immunity via the TLR and cGAS‐STING pathways, therefore converting “cold” tumors into “hot” tumors to achieve high efficacy and long‐term therapeutic outcomes. ABSTRACT Immunotherapy has shed light on clinical oncology for several decades.
Yuqi Yang, Xiaowei Cai, Xiaoyan Zhong, Tian Qiu, Qinwei Lu, Jiahao Qin, Fei Gong, Yecheng Huang, Chenyu Jiang, Youdong Chen, Yuan Cheng, Liang Cheng   +11 more
wiley   +1 more source

Nanodynamic Therapy in Colorectal Cancer: Engineering Precision Immunotherapy and Multimodal Synergy

International Journal of Nanomedicine
Feng Wang,1,* Zhongsong Zhang,2,* Junhao Chen,3,* Lingrong Qian,1,* Bo Chen,4,* Lumei Zhai,5 Junxian Zhao,6 Tianze Chen,7 Jingfeng Zhou,2 Keyi Gou,2 Zihan Zhao,2 Xingcheng Zhu,8 Zhiyuan Xiao1 1Gastrointestinal ...
Wang F, Zhang Z, Chen J, Qian L, Chen B, Zhai L, Zhao J, Chen T, Zhou J, Gou K, Zhao Z, Zhu X, Xiao Z   +12 more
doaj  

Urology HEIRS: A Feasibility and Acceptability Study for Video-Based Research on Physician-Family Communication in Pediatric Urology Visits

Purpose: Patient- and family-centered communication is essential to health care equity. However, less is known about how urologists implement evidence-based communication and dynamics involved in caring for diverse pediatric patients and caregivers.
Rink, R, Dangle, PP, Lester, JN, Koehlinger, J, Dangle, Pankaj P., Whittam, B, Kaefer, Martin, Meldrum, Kirstan, Mattei, Jennifer K., Rink, Richard, Koehlinger, Jeremy, Meldrum, K, Williamson, FA, Szymanski, KM, Kaefer, M, Misseri, R, Roth, Joshua, Lester, Jessica Nina, Mattei, JK, Misseri, Rosalia, Whittam, Benjamin, Williamson, Francesca A., Szymanski, Konrad M., Roth, J   +23 more
core   +1 more source

Loss of CYLD on Chromosome 16q Impairs Homologous Recombination and Genomic Stability Through TIRR Degradation

Advanced Science, EarlyView.
Chromosome 16q loss drives genomic instability through disruption of the CYLD–TIRR–53BP1 axis. CYLD preserves homologous recombination by stabilizing TIRR and limiting 53BP1 accumulation at DNA double‐strand breaks. CYLD deficiency redirects repair toward error‐prone non‐homologous end joining, promotes mutational burden and homologous recombination ...
Mingming Lu, Jialu Kang, Qi Ye, Zixi Wang, Lei Li, Yuzeshi Lei, Leihong Ye, Tianjie Liu, Bin Wang, Tao Liu, Shan Xu, Ke Wang, Yong Zhang, Jian Ma, Lei Li   +14 more
wiley   +1 more source

On Exposure Definition and Temporal Interpretation in the Reported Association Between Number of Pregnancies and Rheumatoid Arthritis [Letter]

International Journal of Women's Health
Wang Lei,1,2 Zhihui Li,1,2 Liang Zhong,1,2 Dongxiang Zheng1,2 1The Tenth Clinical Medical College of Guangzhou University of Chinese Medicine, Zhongshan, Guangdong, People’s Republic of China; 2Zhongshan Hospital of Traditional Chinese Medicine,
Wang L, Li Z, Zhong L, Zheng D
doaj  

GSTM4 Suppresses Prostate Cancer Progression by Targeting TRIM27‐mediated ACLY Ubiquitination and Lipid Metabolism

Advanced Science, EarlyView.
GSTM4 enhances the interaction between ACLY and the E3 ubiquitin ligase TRIM27, thereby increasing K48‐linked ubiquitination at the K554 site of ACLY and promoting its degradation. Consequently, GSTM4 regulates lipid synthesis, as well as the proliferation and metastasis of PCa cells, by modulating ACLY stability.
Kang‐Ping Xiong, Fei Liu, Wang Wang, Gang Wang, Kai‐Yu Qian, Sheng Tu, Si‐Ming Chen, Hui‐Min Xu, Shan‐Shan Zhang, Yong Li, Xing‐Huan Wang, Hong Weng   +11 more
wiley   +1 more source

Engineering Multimodal Nanomaterials for Prostate Cancer Theranostics: Design Principles, Recent Advances, and Translational Challenges

International Journal of Nanomedicine
Jia Wang,1,* Zhongsong Zhang,2,* Haihao Li,3,* Yuanyin Teng,4,* Bo Chen,5,* Jieming Zuo,3 Xiangyun Li,3 Peiqin Zhan,3 Shi Fu,3 Yongqiang Xu,6 Lingxiang Wen,7 Bing Wang,8 Yuanzhi Fu,9 Kehan Qin,2 Wujie Chen,3 ...
Wang J, Zhang Z, Li H, Teng Y, Chen B, Zuo J, Li X, Zhan P, Fu S, Xu Y, Wen L, Wang B, Fu Y, Qin K, Chen W, Huang Y, Shi Y, Chen J, Zhao J   +18 more
doaj  

Integrated O2 and H2 Gas Therapy via Microneedle‐Assisted Photocatalytic Water Splitting for Accelerating Diabetic Full‐Thickness Skin Wound Healing

Advanced Science, EarlyView.
A concept of integrated O2 and H2 gas therapy is achieved using a gas‐producing material. PMP nanoparticles, fabricated from platinum, MIL‐101(Fe)‐NH2, and phosphotungstic acid, are integrated into bilayer gelatin methacryloyl microneedles for transdermal delivery. These microneedles enable integrated O2 and H2 gas therapy and promote wound healing via
Zesheng Chen, Yanchao Yu, Xingyuan Xiao, Wenwen Cheng, Ye Yang, Zhengyao Zhang, Wang Wang, Zhijun Zhou, Weikang Hu, Xiaolong Wang, Bing Li, Kwang Leong Choy, Yun Chen, Zijian Wang   +13 more
wiley   +1 more source

DIXDC1 Promotes Lymphatic Metastasis and Resistance to Cuproptosis in Bladder Cancer Through Mediating DLAT

Advanced Science, EarlyView.
DIXDC1 drives bladder cancer progression by binding and stabilizing DLAT. This axis enhances NEK7 and CCNE2 mRNA stability to promote proliferation and lymphatic metastasis, while limiting copper‐induced DLAT oligomerization to reduce cuproptosis sensitivity, identifying DIXDC1 as a potential target linking metastasis with cuproptosis resistance ...
Hongqiong Li, Liang Cheng, Xiaole Lu, Haonan Dong, Shi Fu, Hongjin Shi, Mingsheng Liu, Chenwei Yang, Yuhang Huang, Zehua Chen, Yawei Zhang, Kaiwen Jie, Xiaoyue Zhang, Xiang Kui, Xinni Ye, Siting Chen, Xu Chen, Haifeng Wang   +17 more
wiley   +1 more source