Results 171 to 180 of about 420,448 (359)

CCT2 Promotes Prostate Cancer Progression Through EIF3F‐Dependent Stabilization of FASN

Advanced Science, EarlyView.
ABSTRACT Prostate cancer (PCa) is increasingly recognized to be driven by dysregulated lipid metabolism. Although fatty acid synthase (FASN) is highly expressed in PCa, the mechanisms governing FASN protein stability and its functional integration into oncogenic lipid metabolism remain poorly defined.
Shun Xu, Yifan Zhang, Haolin Li, Shengyu Zhao, Xiaoran Dai, Qili Xu, Mintian Fei, Chun Li, Zhihui Zou, Baojun Wang, Li Zhang, Hui Wang, Ligang Zhang, Chaozhao Liang   +13 more
wiley   +1 more source

The five amigos: Training and practicing under the living titans of Queen's Urology. [PDF]

Can Urol Assoc J
Nickel JC.
europepmc   +1 more source

Cholesterol‐Mediated Metabolic‐mechanotransductive Crosstalk Orchestrates Castration Resistance in Prostate Cancer

Advanced Science, EarlyView.
Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu, Chao Xu, Jun Jiang, Limin He, Yike Zhou, Zhengxuan Li, Yu Li, Keying Zhang, Fa Yang, Tong Lu, Hongtao Song, Hai Zhu, Zhihao Hu, Xiaolong Zhao, Kai Gan, Hongji Li, Bo Yang, Rui Zhang, Weihong Wen, Donghui Han, Weijun Qin   +20 more
wiley   +1 more source

Artificial intelligence in urology training Enhancing annotation, feedback, and evaluation in robotic, laparoscopic, and endoscopic surgery. [PDF]

Can Urol Assoc J
Han J, He LY, Parmar A, Brako K, Matsumoto ED.   +4 more
europepmc   +1 more source

Impact of Abdominoperineal Resection on Postoperative Male Sexual Function After Minimally Invasive Rectal Cancer Surgery: A Subgroup Analysis From the LANDMARC Study

Annals of Gastroenterological Surgery, EarlyView.
Abdominoperineal resection (APR) after minimally invasive rectal cancer surgery was associated with significantly higher rates of erectile and early ejaculatory dysfunction compared with anal‐sparing surgery. Although ejaculatory function showed partial recovery over time, erectile dysfunction persisted up to 12 months postoperatively.
Taiki Kajiwara, Shinobu Ohnuma, Michiaki Unno, Masakatsu Numata, Tomohiro Yamaguchi, Koya Hida, Tomonori Akagi, Suguru Hasegawa, Akio Shiomi, Ryo Inada, Manabu Shiozawa, Keisuke Kazama, Masanori Hotchi, Masahiko Watanabe, Takeshi Naitoh   +14 more
wiley   +1 more source

Obstructive Sleep Apnea, Circadian Rhythm Disturbance, Hypertension, and Kidney Stone: An Attractive Quadrangle? [Letter]

Nature and Science of Sleep
Sike He, Yunjin Bai Department of Urology, Institute of Urology, West China Hospital, Chengdu, People’s Republic of ChinaCorrespondence: Yunjin Bai, Department of Urology, Institute of Urology, West China Hospital, Chengdu, People’s Republic ...
He S, Bai Y
doaj  

Re-examining equity in urology Evaluating the emergence of unintended bias against male clinicians and academics. [PDF]

Can Urol Assoc J
Khan MZ, Ismail A, Kotb A.
europepmc   +1 more source

Evaluation of Experienced Manipulation Characteristics in Robotic Surgery Using Log Data From the Hinotori Surgical System

Annals of Gastroenterological Surgery, EarlyView.
This study analyzed log data from the Japanese hinotori surgical robot to characterize manipulation performed by experienced surgeons in robotic surgery. Compared with less‐experienced surgeons, the experienced group demonstrated shorter task durations, reduced travel distances with the right instrument (Arm3), faster and more dynamically modulated ...
Masaki Saito, Shunsuke Hayakawa, Hiroyuki Sagawa, Tamiaki Kondo, Masanao Ohashi, Sunao Ito, Reo Sato, Hajime Ushigome, Kenta Saito, Ryo Ogawa, Hiroki Takahashi, Shuji Takiguchi   +11 more
wiley   +1 more source

Evolutionary Frontiers in Urology: Expanding Clinical Care Through Devices and Intelligence. [PDF]

Int Neurourol J
Eun SJ.
europepmc   +1 more source

Real‐World Data of Retroperitoneal Tumor Surgeries Performed by Gastroenterological Surgeons in Japan: Analysis Based on the National Clinical Database

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Retroperitoneal tumors (RPTs) are rare and anatomically complex neoplasms, for which surgery remains the mainstay of treatment. However, real‐world data on their surgical management in Japan have been limited. Objective To describe the clinical characteristics and short‐term outcomes of patients undergoing resection for RPTs in ...
Keisuke Kurimoto, Hiroyuki Yamamoto, Masaki Sunagawa, Yoshiki Kajiwara, Hiroshi Hasegawa, Hideki Ueno, Ken Shirabe, Mitsuro Kanda, Tomoki Ebata, Yukihiro Yokoyama   +9 more
wiley   +1 more source