Results 181 to 190 of about 361,421 (310)

Indirect Comparison of Neoadjuvant Treatment Strategies for Muscle‐Invasive Bladder Cancer: ddMVAC and Perioperative Durvalumab‐Gemcitabine‐Cisplatin Versus Gemcitabine‐Cisplatin: A Systematic Review and Network Meta‐Analysis of Randomised Controlled Trials

open access: yesInternational Journal of Cancer, EarlyView.
Optimizing neoadjuvant therapy for muscle‐invasive bladder cancer patients who are eligible for cisplatin remains difficult, owing particularly to high toxicity and recurrence rates. This meta‐analysis compared dose‐dense methotrexate, vinblastine, doxorubicin, and cisplatin (ddMVAC) against durvalumab plus gemcitabine‐cisplatin (D‐GC) and GC alone ...
Maurin Helen Mangold   +12 more
wiley   +1 more source

Tumor‐Regional Immune Microenvironment: A Critical Factor in the Design of Radiotherapy–Immunotherapy Combination Trials

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Clinical trials combining radiotherapy (RT) with immune checkpoint blockade (ICB) have shown improved outcomes in only a fraction of patients, and optimal strategies for integrating these modalities remain under intense investigation. With a few exceptions, phase III combination trials have yielded disappointing results.
Xuanwei Zhang   +10 more
wiley   +1 more source

Geographical Pattern of Testicular Cancer Points to Maternal Exposures Behind Increasing Incidence

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Evidence suggests that testicular cancer (TC) originates from germ cell neoplasia in situ arising during fetal development, implying that prenatal environmental exposures may influence disease risk. We investigated whether maternal place of residence during pregnancy is associated with regional variation in TC incidence.
Antti Kaipia   +8 more
wiley   +1 more source

Comparison of Relapse Risk Prediction Models During Active Surveillance in Stage I Seminoma: A Retrospective Multicenter Cohort Study

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT To improve the prediction of relapse for clinical stage I seminoma, we aimed to validate the Boormans model (incorporating tumor size, rete testis invasion, and lymphovascular invasion) against the conventional classification (tumor size > 4 cm/rete testis invasion).
Andreas Banner   +15 more
wiley   +1 more source

Migration status and urologic health inequities: a scoping review. [PDF]

open access: yesCurr Opin Urol
Goodarzi K   +4 more
europepmc   +1 more source

Urethral injury during vaginal delivery: Incidence, management and long‐term outcomes

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study examines the incidence, obstetric risk factors, surgical management, and long‐term outcomes of obstetric‐associated urethral injuries during vaginal deliveries. Methods A retrospective case series was conducted at a single, tertiary university‐affiliated medical center between January 2018 and December 2023.
Yoav Baruch   +5 more
wiley   +1 more source

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