Results 201 to 210 of about 450,591 (305)

SPARK: A webserver for comprehensive search and analysis of testicular single‐cell transcriptomic data covering full lifecycle and pathology

open access: yesiMetaOmics, EarlyView.
SPARK is an interactive platform hosting 189,232 human testicular single‐cell transcriptomes across normal and infertile conditions. It enables automated, code‐free analysis and visualization, providing a powerful resource to explore cellular and molecular dynamics in male reproduction and infertility.
Lina Cui   +9 more
wiley   +1 more source

A Study to Evaluate Efficacy and Safety of Hydeal Cyst Intravesical Instillations in Non-muscle Invasive Bladder Cancer Patients Treated With Intravesical Chemotherapy or Immunotherapy. [PDF]

open access: yesEur Urol Open Sci
Callegarin F   +13 more
europepmc   +1 more source

Progress of metabolomics‐centric multi‐omics research in medicine

open access: yesiMetaOmics, EarlyView.
The graphical abstract illustrates a holistic roadmap for metabolomics‐centric multi‐omics integration in medical research. The upper panel depicts the technological transition from traditional bulk analysis to high‐resolution single‐cell and spatial methodologies, specifically addressing inherent challenges such as molecular complexity and dynamic ...
Ziyi Wang   +6 more
wiley   +1 more source

Correction: Three-dimensional image reconstruction technology in laparoscopic pyeloplasty for horseshoe kidney-associated ureteropelvic junction obstruction: a case series study. [PDF]

open access: yesBMC Urol
Kandori S   +15 more
europepmc   +1 more source

Patient‐derived organoid‐immune co‐cultures integrated with multi‐omics reveal immunotherapy resistance mechanisms in urothelial carcinoma

open access: yesiMeta, EarlyView.
Immunotherapy resistance presents a formidable challenge in tumor biology. While fibroblast growth factor receptor 3 (FGFR3) serves as a pivotal oncogenic driver in a multitude of cancers, the exploration of its role in immune checkpoint inhibitor (ICI) resistance remains scarce, thus impeding a deeper understanding of the tumor immune microenvironment
Shan Jiang   +12 more
wiley   +1 more source

Does Margin Length Predict Recurrence After Partial Nephrectomy, or Is Presence Alone Sufficient? [PDF]

open access: yesJ Kidney Cancer VHL
Oğuz U   +22 more
europepmc   +1 more source

Integrating Prostate‐Specific Antigen Density and Prostate Imaging Reporting and Data System Scores to Optimize Detection of Clinically Significant Prostate Cancer: A Multivariable Risk Model Approach

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
For the detection of clinically significant prostate cancer, incorporating PSA density into PI‐RADS‐based assessment improved clinical net benefit compared with PI‐RADS alone. The addition of DRE and age to this combined model produced only marginal further gain, indicating that most of the incremental clinical value was derived from PSA density rather
Yunus Kayali
wiley   +1 more source

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