Results 41 to 50 of about 438,216 (309)

Patients With Kidney Cancer [PDF]

, 2012
To develop a preoperative prognostic model in order to predict recurrence-free survival in patients with nonmetastatic kidney cancer.A multi-institutional data base of 1889 patients who underwent surgical resection between 1987 and 2007 for kidney cancer
B. Soyupak, C. Gogus, E. Karabulut, H. Ozen, L. Turkeri, null null, O. Yaycioglu, S. Eskicorapci, S. Yazici, T. Divrik   +9 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

REVIEW OF EAU GUIDELINES ON THE TREATMENT AND FOLLOW-UP OF NON-NEUROGENIC MALE LOWER URINARY TRACT SYMPTOMS INCLUDING BENIGN PROSTATIC OBSTRUCTION

Вестник урологии, 2014
Original Authors: Matthias Oelkea , Alexander Bachmannb , Aure´lienDescazeaudc , Mark Embertond , Stavros Gravas e , Martin C. Michelf , James N’Dowg , Jørgen Nordlingh , Jean J.
K. L. Lokshin
doaj   +1 more source

Prostatic Therapeutic Efficacy of LENILUTS^®, a Novel Formulation with Multi-Active Principles

Pharmaceutics, 2022
Lower Urinary Tract Symptoms (LUTs) in men are usually associated to benign prostatic hyperplasia (BPH), a non-malignant prostate enlargement. Unfortunately, BPH etiology is still unclear.
Erik Tedesco, Federico Benetti, Simone Castelli, Andrea Fratter   +3 more
doaj   +1 more source

Complications of circumcision in male neonates, infants and children: a systematic review. [PDF]

, 2010
BACKGROUND: Approximately one in three men are circumcised globally, but there are relatively few data on the safety of the procedure. The aim of this paper is to summarize the literature on frequency of adverse events following pediatric circumcision ...
Halperin, Daniel, Larke, Natasha, Schenker, Inon, Weiss, Helen A   +3 more
core   +2 more sources

Geriatric Urology [PDF]

Journal of the American Geriatrics Society, 2003
Urology is one of the surgical specialties that has been most affected by the growing demographic of older adults in the United States. Urological problems are common in elderly people, and care of patients aged 65 and older represents a large proportion of many urologists' practices.
George W, Drach, Tomas L, Griebling
openaire   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Accuracy of magnetic resonance imaging to identify pseudocapsule invasion in renal tumors [PDF]

, 2020
Purpose: To evaluate accuracy of MRI in detecting renal tumor pseudocapsule (PC) invasion and to propose a classification based on imaging of PC status in patients with renal cell carcinoma.
Altobelli, Emanuela, Angeletti, Silvia, Bellangino, Mariangela, Catalano, Carlo, Ciccozzi, Massimo, Del Monte, Maurizio, D’ovidio, Giulia, Faiella Eliodoro, Gallucci, Michele, Grasso, Francesco Rosario, Mastroianni, Riccardo, Muto, Giovanni, Panebianco, Valeria, Papalia, Rocco, Scarpa, Roberto Mario, Simone, Giuseppe   +15 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Attitude and perception of urology by medical students at the end of their medical school: An appraisal from Saudi Arabia

Urology Annals, 2015
Objectives: To evaluate the attitude and perception of the graduates of King Saud University (KSU) College of Medicine regarding the quality of their urology rotation, urology exposure during this rotation, confidence about managing common conditions ...
Saleh Binsaleh, Abdulrahman Al-Jasser, Raed Almannie, Khaled Madbouly   +3 more
doaj   +1 more source