Results 151 to 160 of about 3,069,601 (247)

Cancer Trends: Childhood cancer

, 2017
This is the second trends report NCRI has published on childhood cancers, updating a previous report covering 1994-20111. To facilitate summary of the amount and complexity of material included, presentation and layout has been in general retained from ...
National Cancer Registry Ireland (NCRI)
core  

Towards sustainable multidisciplinary renal cancer tumour boards: redesigning the referral pathway

BJU International, EarlyView.
Objectives To develop and evaluate a complexity‐stratified referral pathway aimed at improving the sustainability, efficiency and resource utilisation of specialist multidisciplinary team (SMDT) meetings within a high‐volume tertiary renal cancer service.
Bhargab Ghoshal, Sarika Nalagatla, Max Roberts, Adam Mann, David Cullen, Victoria Horsfall, Andrea Da Silva, Abhishek Reekhaye, Prasad Patki, Ravi Barod, Faiz Mumtaz, Axel Bex   +11 more
wiley   +1 more source

Advances in Therapy for Urothelial and Non-Urothelial Subtype Histologies of Advanced Bladder Cancer: From Etiology to Current Development

Urothelial carcinoma (UC) is the most common histological subtype of bladder tumors; however, bladder cancer represents a heterogeneous group of diseases with at least 40 distinct histological subtypes.
Ho Kyung Seo, Min-Kyung Lee, Geehyun Song, Weon Seo Park, Whi-An Kwon   +4 more
core   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Cardiac surveillance in immune checkpoint inhibitor therapy: Insights from the Essen Cardio‐oncology Registry

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Immune checkpoint inhibitors (ICI) have revolutionized cancer therapy, offering improvements in survival across various malignancies. However, their toxicities pose a major challenge for cardio‐oncology units. Despite their growing importance, data on effectiveness of such specialized units in mitigating ICI‐associated ...
Elias Haj‐Yehia, Lisa Zimmer, Lena Lampe, Dimitra Vlachopoulou, Matthias Totzeck, Tienush Rassaf, Raluca I. Mincu   +6 more
wiley   +1 more source

Targeting KRAS for cancer therapy

British Journal of Pharmacology, EarlyView.
In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia, Ruonan Liu, Tonia A. Adamide, Isis E. Fernandez, Georgios T. Stathopoulos   +4 more
wiley   +1 more source

Arrhythmias associated with immune checkpoint inhibitor therapy—A clinical perspective

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy but are associated with a growing spectrum of cardiovascular immune‐related adverse events. Among these, arrhythmias represent a rare yet potentially life‐threatening complication. ICI‐induced arrhythmias encompass a wide clinical spectrum, including atrial arrhythmias, conduction ...
Dong Wang, Melanie Ricke‐Hoch, David Duncker, Johann Bauersachs, Dominik Berliner   +4 more
wiley   +1 more source

An Audit of Nephroureterectomy for Upper Tract Urothelial Carcinoma

, 2011
Background: The boundary of nephroureterctomy has been revisited and lymph node dissection has been recommended recently. We investigated the role of synchronous ipsilateral adrenalectomy in treating patients with upper tract urothelial carcinoma ...
黃昭淵;鍾旭東;王碩盟;廖俊厚;賴明坤;黃國皓;蒲永孝;闕士傑;余宏政, HUANG, CHAO-YUAN;CHUNG, SHIU-DONG;WANG, SO-MONG;LIAO, CHUN-HOU;LAI, MING-KUEN;HUANG, KUO-HOW;PU, YEONG-SHIAU;CHUEH, SHIH-CHIEH;YU, HONG-JENG   +1 more
core  

Long non‐coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets

British Journal of Pharmacology, EarlyView.
Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff, Pamela Calle‐Mendoza, Maria Hatziapostolou, Christos Polytarchou   +3 more
wiley   +1 more source

Submucosal urothelial cancer of bladder: A case report. [PDF]

Urol Case Rep
Sappayasarn S, Sirisreetreerux P, Setthawong T, Srithongsongsaeng P, Chaikitti J, Jirajan V.   +5 more
europepmc   +1 more source