Results 31 to 40 of about 3,069,601 (247)

Cutaneous invasion from sarcomatoid urothelial carcinoma: clinical and dermatopathologic features [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2016
In Brazil, without considering the non-melanoma skin tumors, bladder cancer in men is the eighth most common, and the urothelial carcinoma or transitional cell carcinoma is the most common among these.
Fred Bernardes Filho   +6 more
doaj   +1 more source

Differential Regulation of Growth-Promoting Signalling Pathways by E-Cadherin [PDF]

open access: yes, 2010
Background: Despite the well-documented association between loss of E-cadherin and carcinogenesis, as well as the link between restoration of its expression and suppression of proliferation in carcinoma cells, the ability of E-cadherin to modulate growth-
Dawn C Walker   +18 more
core   +2 more sources

Expression of RFC/SLC19A1 is associated with tumor type in bladder cancer patients. [PDF]

open access: yesPLoS ONE, 2011
Urinary bladder cancer (UBC) ranks ninth in worldwide cancer. In Egypt, the pattern of bladder cancer is unique in that both the transitional and squamous cell types prevail.
Alyaa M Abdel-Haleem   +7 more
doaj   +1 more source

The application of artificial intelligence to microarray data: identification of a novel gene signature to identify bladder cancer progression [PDF]

open access: yes, 2009
Background: New methods for identifying bladder cancer (BCa) progression are required. Gene expression microarrays can reveal insights into disease biology and identify novel biomarkers.
Wild, P J   +50 more
core   +1 more source

Immortalisation of Normal Human Urothelial Cells Compromises Differentiation Capacity. [PDF]

open access: yes, 2011
BACKGROUND: The development of urothelial malignancy is not solely a consequence of loss of proliferation constraints but also involves loss of cellular differentiation, defined histopathologically as grade.
Nicola J. MacLaine   +11 more
core   +1 more source

Driven Urothelial Cancer

open access: yes, 2023
International audienceSeveral fibroblast growth factor receptor (FGFR) inhibitors are approved or in clinical development for the treatment of FGFR-driven urothelial cancer, and molecular mechanisms of resistance leading to patient relapses have not been
Hayato Mizuta   +43 more
core   +1 more source

Emerging Treatment Options for the Treatment of Metastatic Urothelial Cancer: Therapeutic Potential of Enfortumab Vedotin

open access: yesCancer Management and Research, 2020
Rohit K Jain, William Paul Skelton IV, Jingsong Zhang Department of Genitourinary Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USACorrespondence: Jingsong ZhangDepartment of Genitourinary Oncology, H.
Jain RK, Skelton WP IV, Zhang J
doaj  

The role of circulating tumor DNA (ctDNA) in urothelial cancers [PDF]

open access: yesExploration of Targeted Anti-tumor Therapy
The role of circulating tumor DNA (ctDNA) in urothelial cancers is a rapidly evolving area of research. Urothelial cancer is the most common subtype of bladder cancer, and biomarkers that predict response or prognosticate outcomes have been long sought ...
Jeanny B. Aragon-Ching
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Phases of tight junction barrier disruption during transurothelial migration of invasive urothelial cancer cells

open access: yesScientific Reports
Bladder cancer is characterised by its multifocal nature and a high recurrence, yet the underlying mechanisms of these phenomena remain only partially understood. In the present study, we aimed to investigate transurothelial invasion of urothelial cancer
Tadeja Kuret   +5 more
doaj   +1 more source

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