Results 191 to 200 of about 114,562 (319)

The tumor-associated fibroblasts regulate urothelial carcinoma progression. [PDF]

open access: yesJ Mol Cell Biol
Xiao Y   +15 more
europepmc   +1 more source

The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi   +5 more
wiley   +1 more source

Antibody–Drug Conjugates in Oncology: Principles, Clinical Development, and Future Directions

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Antibody–drug conjugates integrate antibody targeting with potent cytotoxic payloads to enable precision cancer therapy. Their clinical performance depends on coordinated optimization of engineering design, tumor antigen biology, and treatment strategy. Lessons from uro‐oncological malignancies illustrate how ADCs can be effectively developed, combined,
Bisheng Cheng   +6 more
wiley   +1 more source

High-Grade Urothelial Carcinoma Arising From a Ureteral Diverticulum: A Rare Case Report. [PDF]

open access: yesIJU Case Rep
Papadopoulos I   +9 more
europepmc   +1 more source

Chromosome 1 Open Reading Frame 35 Drives Colorectal Cancer Progression by Enhancing Tumor‐Intrinsic Proliferation and CD8+ T Cell Suppression

open access: yesMedComm, Volume 7, Issue 4, April 2026.
This study identifies C1orf35 as a key driver of colorectal cancer progression through a dual mechanism. It promotes tumor‐intrinsic cell proliferation and migration via the c‐Myc/PYCR2 axis, and suppresses anti‐tumor immunity by impairing CD8+ T‐cell immune surveillance, nominating it as a novel therapeutic target in colorectal cancer.
Shaosen Zhang   +6 more
wiley   +1 more source

Labels, Language and Other Strategies to Improve Communication About Lowest Grade Ductal Carcinoma in Situ: Qualitative Interviews With Women and Physicians

open access: yesPsycho-Oncology, Volume 35, Issue 4, April 2026.
ABSTRACT Objective Women diagnosed with ductal carcinoma in situ (DCIS) and clinicians have reported challenges in communication about DCIS, contributing to women's confusion and anxiety. This study explored how to improve communication about DCIS including alternative labels, language and other strategies.
Suzanna Apostolovski   +3 more
wiley   +1 more source

Early Recognition of Immune-Related Hepatitis During Avelumab Maintenance Therapy for Urothelial Carcinoma. [PDF]

open access: yesIJU Case Rep
Iwama Y   +9 more
europepmc   +1 more source

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